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Lauded for its success and heralded as an economic model for peripheral European countries to follow, since the bursting of the Irish property bubble in 2008 the management of the Celtic Tiger by the Irish state has been castigated as expressively how not to manage an economic bubble. Following a decade and a half of continuous growth averaging over six per cent, the Irish economy has since experi

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Popular Science Summary Konsten att kunna ta bort ett syre Alla celler har DNA, som måste repareras och kopieras för att livet ska fortgå. För att kunna göra detta måste det finnas byggstenar. En av alla processer som ser till att alla delar finns i rätt mängd innefattar bara ett protein. Ett protein som får instruktioner från många håll för att gå igenom en komplicerad process som tillverkar dessThe protein ribonucleotide reductase catalyses the de novo synthesis of deoxyribonucleotides (dNTPs) from ribonucleotides (NTPs), using radical chemistry. It is under strict allosteric regulation, partly from the dNTPs it synthesises that regulate what substrate should be synthesised, but also from dATP/ATP, which regulates overall activity. It is a protein that is found in almost every living org

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Housing expenditure is without doubt one of the biggest expenditure posts for all households. By using econometrics to estimate regressions with cross-­‐sectional data including more than 1500 individuals, this thesis examines whether there is any individual characteristics that determines how big a share of the disposable income that is spent on housing each month. The results indicate that diffe

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Phonological vowel reduction in Bulgarian is discussed, distinguishing between formal & informal speech & dialectal & standard forms. The Bulgarian vowel system is presented, with an evaluation of the articulatory models of Bulgarian vowel production, & a description of the orthographic representation of the "indeterminate vowel." Alternations between stressed & nonstressed vow

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The anticancer active complex cisplatin interacts preferentially with the common, G - C rich, wobble base pair region of both tRNA(Ala) and Mh(Ala) in a reaction that at pH 6.3 is rate limited by the acid hydrolysis of the metal complex.

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Inhibitors of the enzyme dipeptidyl peptidase IV (DPP IV) are of increasing interest to both diabetologists and the pharmaceutical industry alike, as they may become established as the next member of the oral antidiabetic class of therapeutic agents, designed to lower blood glucose and, possibly, prevent the progressive impairment of glucose metabolism in patients with impaired glucose tolerance a

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In this paper the Dirichlet problem for a class of standard weighted Laplace operators in the upper half plane is solved by means of a counterpart of the classical Poisson integral formula. Boundary limits and representations of the associated solutions are studied within a framework of weighted spaces of distributions. Special attention is given to the development of a, suitable uniqueness theory

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The electronic structure of strongly correlated systems is usually calculated by using an effective model Hamiltonian with a small number of states and an effective on-site interaction. The mode, however, neglects the frequency dependence of the interaction, which emerges as a result of dynamical screening processes not included in the model. The self-energy calculated in this kind of model within

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Traditional, pre-industrial farming was adapted to the natural environment-topography, geology, hydrology, climate, and biota. Traditional land use systems are still to be traced in Scandinavia as an "infield/outland landscape", and in Japan as a "Satoyama landscape." There are obvious similarities and differences in land use-the main difference being that pasturing of cattle and sheep has been le

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BACKGROUND: The two-gene expression ratio HOXB13:IL17BR has been proposed to predict the outcome of tamoxifen-treated breast cancer patients. We intended to examine whether this ratio can predict the benefit of 5 years vs. 2 years of tamoxifen treatment of postmenopausal patients. A further objective was to investigate any prognostic effects of the ratio in systematically untreated premenopausal p

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Hormone-mediated maternal effects play an important role in the formation of a differentiated phenotype. They have been shown to influence a wide array of offspring traits, both early in life and in adulthood. One important offspring trait that is under the influence of maternal androgens is the immune system. In birds, a growing number of studies show that yolk androgens modulate immune function

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This thesis primarily concerns the European Union (EU) value added tax (VAT) exemption for insurance transactions. Due to the negative consequences that exemptions have on the proper functioning of the VAT system and those subject to it, this thesis explores the possibility of adopting the Kiwi taxed approach for insurance transactions. In order to do this, the provisions and functioning of both t

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This case study investigates the development of subject-specific literacy in Physical Education and Health (PEH) for second language (L2) learners within a Swedish secondary school context. Integrating Systemic Functional Linguistics (SFL) and Legitimation Code Theory (LCT), the study introduces the concept of embodied cohesion to analyze how meaning is constructed across verbal, graphic, and phys

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Antipsychotic drugs (APD) are commonly prescribed to people living with dementia (PwD) to manage behavioral and psychological symptoms of dementia (BPSD), despite well-documented safety concerns. International guidelines recommend non-pharmacological interventions as first-line treatment, yet APDs remain widely used. This systematic review and meta-analysis synthesize current evidence on the conse