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Shrubs have increased in abundance and dominance in arctic and alpine regions in recent decades. This often dramatic change, likely due to climate warming, has the potential to alter both the structure and function of tundra ecosystems. The analysis of shrub growth is improving our understanding of tundra vegetation dynamics and environmental changes. However, dendrochronological methods developed
Background: Type 2 diabetes and its cardiovascular disease complications are the major public health threats of our century. Although physical activity and dietary changes are the cornerstones in prevention of diabetes, their broad implementation is not elementary and other complementary lifestyle regimens are needed. Summary: Vasopressin (VP) is the main regulator of body water homeostasis, and a
We propose a signal-to-noise criterion which predicts whether a feature of a given size and scattering strength, placed inside a larger object, can be retrieved with two common X-ray imaging techniques: coherent diffraction imaging and projection microscopy. This criterion, based on how efficiently these techniques detect the scattered photons and validated through simulations, shows in general th
In every human being, there is a substantial proportion (1-2 kg) of total body weight constituted by the gut microbiota content in the gastro-intestinal system. Recent research findings, based on mapping of the microbiome, have stated that in healthy subjects, the gut microbiota richness and diversity is higher as compared to obese subjects or patients suffering from cardiometabolic disease, or ev
Mixed cultures of a heterotrophic nitrifier/aerobic denitrifier, Thiosphaera pantotropha, and an autotrophic nitrifier, Nitrosomonas europaea, were grown in chemostats under dual ammonia-and acetate limitation. Because of simultaneous nitrification and denitrification by T. pantotropha, the activity of the cultures was evaluated from nitrogen balances as complete as possible. Under most conditions
The FragMAX facility at MAX IV Laboratory is a state-of-the-art platform for crystallographic fragment screening, designed to support structure-based drug and chemical tool compound discovery. This facility offers a comprehensive workflow, from high-throughput crystal preparation and automated diffraction data collection at the BioMAX beamline to advanced data processing and analysis using custom
This textbook covers the mathematics needed to model, analyze, and design feedback systems. Now more user-friendly than ever, this revised and expanded edition of Feedback Systems is a one-volume resource for students and researchers in mathematics and engineering. It has applications across a range of disciplines that utilize feedback in physical, biological, information, and economic systems. Ka
BackgroundTo enable people with stroke to achieve an active everyday life under altered conditions, the development of self-management programs is essential to facilitate the process of change that individuals must undergo. To improve access to self-management, internet-based solutions have been proposed. The aim of this study was to evaluate the feasibility of a novel internet-based intervention,
A growing body of observations has revealed rapid changes in both the total inventory and the distribution of marine oxygen over the latter half of the 20th century, leading to increased interest in extending oxygenation records into the past. The use of paleo-oxygen proxies has the potential to extend the spatial and temporal range of current records, constrain pre-anthropogenic baselines, provid
The European Spallation Source (ESS) is a research facility under construction aiming to be the world’s most powerful pulsed neutron source. It is powered by a complex particle accelerator designed to provide a 2.86 ms long proton pulse at 2 GeV with a repetition rate of 14 Hz. Protons are accelerated via cavity fields through various accelerating structures that are powered by Radio-Frequency (RF
Solid dispersions are promising drug delivery forms which offer the possibility to disperse a hydrophobic drug in a hydrophilic matrix and thereby improve the dissolution behavior and the bioavailability of the drug. One important aspect and a prerequisite in understanding the drug dissolution mechanism from solid dispersions is a better analytical monitoring of the solid dispersion surface proper
Quantum technologies and experiments often require preparing systems in low-temperature states. Here we investigate cooling schemes using feedback protocols modeled with a quantum Fokker-Planck master equation (QFPME) recently derived by Annby-Andersson et al. [Phys. Rev. Lett. 129, 050401 (2022)0031-900710.1103/PhysRevLett.129.050401]. This equation describes systems under continuous weak measure
Mitochondrial replacement therapy has been developed in order to prevent the transmission of mitochondrial mutations, yet it raises ethical concerns, particularly regarding the involvement of third-party DNA and the risks associated with donor procedures. This paper explores an alternative approach using synthetic DNA (synDNA) to construct mitochondrial organelles, thereby bypassing the need for d
J. S. Wilson proved in 1971 an isomorphism between the structural lattice associated to a group belonging to his second class of groups with every proper quotient finite and the Boolean algebra of clopen subsets of Cantor’s ternary set. In this paper we generalize this isomorphism to the class of branch groups. Moreover, we show that for every faithful branch action of a group G on a spherically h
Virtual reality (VR) is a technology that offers near real-world experiences in various fields. With the widespread use of virtual environments designed to provide VR experiences, the amount of data collected from these environments has increased rapidly. However, as the volume of data grows, there is a need to develop analysis processes and advance the data-driven development model. In this study
During the past decade, scholars have produced a vast amount of research using linked historical individual-level data, shaping and changing our understanding of the past. This linked data revolution has been powered by methodological and computational advances, partly focused on supervised machine-learning methods that rely on training data. The importance of obtaining high-quality training data
The emergence of cyber mistreatment among frontline workers in their digital interactions with customers, clients and patients represents a significant but relatively new work environment risk within the service sector. Human resource management has a key role in digital transformation, which includes securing safe and healthy workplaces and fostering sustainable practices for handling cyber mistr
