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Antibody microarrays have emerged as an important tool within proteomics, enabling multiplexed protein expression profiling in both health and disease. The design and performance of antibody microarrays and how they are processed are dependent on several factors, of which the interplay between the antibodies and the solid surfaces plays a central role. In this study, we have taken on the first com
The flat periwinkles, Littorina fabalis and L. obtusata, comprise two sister gastropod species that have an enormous potential to elucidate the mechanisms involved in ecological speciation in the marine realm. However, the molecular resources currently available for these species are still scarce. In order to circumvent this limitation, we used RNA-seq data to characterize the transcriptome of fou
This study investigates how related variety in the regional employment mix affects the innovation output of a region. Departing from the idea of recombinant innovation, previous research has arguedthat related variety enhances regional innovation as inter-industry knowledge spillovers occur more easily between different but cognitively similar industries. This study combines a
Animal models of Parkinson's disease (PD) are essential to investigate pathogenic pathways at the whole-organism level. Moreover, they are necessary for a preclinical investigation of potential new therapies. Different pathological features of PD can be induced in a variety of invertebrate and vertebrate species using toxins, drugs, or genetic perturbations. Each model has a particular utility and
During the process of its socio-economic development, Vietnam has been achieving the remarkable successes in poverty reduction, and the economic growth that is recognized by the World Bank, the Asian Development Bank and the international communities. However, the fast industrialization and urbanization are attracting the increasing inflow of rural migrants to urban areas. Besides that, the govern
In this thesis, employment and earnings differentials between visually or hearing-impaired and non-disabled Swedish workers are analyzed. The thesis investigates whether there are any differences and if so, how large, in the earnings and the employment probabilities of the visually or hearing-impaired and the non-impaired on the Swedish labor market. Due to the detailed measures of visual acuity a
Before the twentieth century, there was little concern with ship-source oil pollution at sea. Increase of shipping activities and in particular happening of disasters, the most important of which is the Torrey Canyon, alerted the thinking of legislators as to seriousness of the problem of marine pollution. The result of their efforts in private law domain was creating the Civil Liability Conventio
The thesis sets out to study the correlation between long-run economic growth and climate, through testing two hypotheses. In the first hypothesis Montesquieu’s climate theory is compared to a modern approach, while in the second hypothesis, natural disaster and disease ecology variables are suggested and tested as growth determinants. In the application of multiple regression analysis two signifi
The company, qpunkt GmbH, recently developed a concept for an “innovative” thermal manikin – the Klimadummy. Before a decision can be made whether to realize the production of their manikin, there is a need for a market research, describing the current situation of the thermal manikin market, including the competitors and customers. Purpose: The purpose of the thesis is to describe and analyze the
A methodology is produced for environmental and health risk assessment for road transports of hazardous material. The general risk management process with focus on health and environment is described briefly. Management systems, risk communication and uncertainty in the risk management process are also discussed in this context. The produced methodology is implemented in a case study in Iceland. T
The purpose of this research was to examine how non-mandatory municipal environmental work is carried out. What drives certain municipalities to be more active than others, and what works as barriers? It was also of interest to understand if the mandatory work could influence, trigger or hinder other environmental goals and ideas. Further, the research looked to identify some characteristics that
Abstract in Danish Denne afhandling handler om livskvalitet hos ældre mennesker med kræft. Risikoen for at få kræft stiger med alderen, og til trods for at de fleste mennesker, der får kræft er ældre, har forskning i hvordan ældre lever med en kræftsygdom været yderst begrænset. Viden om hvordan ældre mennesker oplever det at få en kræftdiagnose og hvordan de lever med sygdommen er en forudsætningOver the coming decades, the numbers of elderly will increase, and through improved lifestyles and better treatment longevity has increased, and with it, the risk of contracting cancer. How elderly people live with cancer has until now attracted limited research. The overall aim of this thesis was to investigate the QoL of elderly persons from the time of a cancer diagnosis through the following s
This paper presents a model for reversed-phase purification of insulin from desamido insulin. The system is described by a reaction dispersive model with a competitive Langmuir isotherm. A model building and calibration method is presented and the model's region of validity is defined. The model is calibrated using only two-component experiments on the raw mixture by the inverse method and then ex
Forestry in Sweden suffers from browsing damage caused by large herbivores, mainly moose (Alces alces) and roe deer (Capreolus capreolus). Silviculture affects the availability of forage for these animals, and thus the browsing pressure. A step towards modeling the response of trees or to predict browsing damage is to gain more knowledge on the availability of food in forest stands. Individual gap
A seismic approach is used to estimate the thickness and elastic stiffness constants of asphalt or concrete slabs. The overall concept of the approach utilizes the robustness of the multichannel seismic method. A multichannel-equivalent data set is compiled from multiple time series recorded from multiple hammer impacts at progressively different offsets from a fixed receiver. This multichannel si
Wave cycles, i.e. pairs of local maxima and minima, play an important role in many engineering fields. Many cycle definitions are used for specific purposes, such as crest-trough cycles in wave studies in ocean engineering and rainflow cycles for fatigue life prediction in mechanical engineering. The simplest cycle, that of a pair of local maximum and the following local minimum is also of interes
The Multi-plume Aerosol dynamics and Transport (MAT) model has been developed to study the dynamics of the particle size distribution in urban environments. The MAT model uses a novel multi-plume scheme for vertical dispersion and routines of the aerodynamics models AERO3. It treats the processes: emission from a near ground source, dilution with background air, deposition, coagulation and condens
