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Background and aims: PPARGC1A encodes PGC-1α (peroxisome proliferator-activated receptor γ coactivator 1-α), a central regulator of energy metabolism and mitochondrial function. A common polymorphism in PPARGC1A (rs8192678, C/T, Gly482Ser) has been associated with obesity and related metabolic disorders, but no published functional studies have investigated direct allele-specific effects in adipoc

Breathlessness is common in the general population. Existing data were obtained primarily with the uni-dimensional modified Medical Research Council breathlessness scale (mMRC) that does not assess intensities of unpleasantness nor physical, emotional and affective dimensions. The aim of this research was to determine the prevalence and intensity of these dimensions of breathlessness in elderly ma

IntroductionThe implementation of welfare technologies in Swedish eldercare reflects ongoing sociotechnical transitions, which promise to optimise care practices and administrative processes. AimOur study explores how eldercare personnel interpret and ascribe meanings to welfare technologies in their everyday care work.Material and MethodsThe study draws on an empirical dataset comprising 181 phot

Introduction: Home oxygen therapy is one of the few interventions that can improve survival in patients with chronic obstructive pulmonary disease (COPD) when administered appropriately, although it may cause side effects and be an unnecessary burden for some patients. Areas covered: This narrative review summarizes the current literature on the assessment of hypoxemia, different types of home oxy

X-ray phase-contrast imaging by grating interferometry has in the past decades been established both at synchrotron radiation sources and at conventional x-ray tubes. Due to the sensitivity to x-ray phase shifting, contrast in soft tissue has been improved significantly and the possibilities to do virtual histology of tissue biopsies are being pioneered. Constraints in the design of a grating inte

This paper focuses on the intersection of social dynamics, knowledge production, and the implementation of identity features in robotic platforms. Concentrating on the concept of epistemic injustice, particularly in the context of trust, the study highlights the potential for justified distrust based on experienced injustice. The incorporation of social identity features, such as gender, signals g

Microbicides in the leather industries are employed to avoid the biodeterioration of the hides by microorganisms. This problem may lead to harmful characteristics to the end product such as stains, roughness and decrease mechanical properties of leather. Therefore, microbicides like the 2-(thiocyanomethylthio) benzothiazole (TMCTB) are applied in distinct steps of the tanning process as alternativ

Background: Small-bore chest drains are now the most common drains for treating pleural effusion (PE), but knowledge on complications is limited especially in malignant PE and empyema. We aimed to evaluate rate of complications of ultrasound guided small bore chest drains [6–10 French (F)] by PE etiology. Methods: Retrospective cohort study of 484 chest drains inserted in 330 adults in a Swedish d

BACKGROUND: Patients with chronic respiratory failure treated with long-term oxygen therapy (LTOT) often have severe breathlessness, impaired exercise performance, and high but variable mortality that is difficult to predict. We aimed to evaluate breathlessness and exercise performance upon starting LTOT as predictors of overall and short-term mortality.METHODS: This was a longitudinal, population

Breathlessness is a centrally processed symptom, as evidenced by activation of distinct brain regions such as the insular cortex and amygdala, during the anticipation and/or perception of breathlessness. Inhaled L-menthol or blowing cool air to the face/nose, both selective trigeminal nerve (TGN) stimulants, relieve breathlessness without concurrent improvements in physiological outcomes (e.g., br

Background Exertional breathlessness is commonly assessed using incremental exercise testing (IET), but reference equations for breathlessness responses are lacking. We aimed to develop reference equations for breathlessness intensity during IET. Methods A retrospective, consecutive cohort study of adults undergoing IET was carried out in Sweden. Exclusion criteria included cardiac or respiratory

Objectives: In India, cervical cancer is the most common cancer among women and makes up for up to 29% of all registered cancer in females. Cancer-related pain is one of the major distressing symptoms for all cancer patients. Pain is characterised as somatic or neuropathic, and the total pain experience is often mixed. Conventional opioids are the backbone of analgesic treatment but are most often

The European Food Safety Authority (EFSA) är en EU myndighet med uppdrag att göra riskbedömningar för att stödja arbete med att upprätthålla livsmedelssäkerhet i EU. I denna studie undersöks hur EFSA kommunicerar osäkerhet i slutsatser från några av deras vetenskapliga bedömningar och om de följer den rekommenderade guiden som antogs av EFSA 2019 för kommunikation av osäkerhet. I studien har 15 stThe European Food Safety Authority (EFSA) is an EU agency, providing scientific advice and standards surrounding risk assessment in order to maintain food safety in Europe. The aim of this study was to investigate how EFSA communicates uncertainty in conditions of their assessment and if the recommended guidelines by EFSA 2019 is fulfilled. 15 Randomly picked scientific articles produced during th

Identification of Non-HLA Genes Associated with Celiac Disease and Country-Specific Differences in a Large, International Pediatric Cohort RESEARCH ARTICLE Identification of Non-HLA Genes Associated with Celiac Disease and Country-Specific Differences in a Large, International Pediatric Cohort Ashok Sharma1, Xiang Liu2, David Hadley2,3, William Hagopian4, Edwin Liu5, Wei- Min Chen6, Suna Onengut-G

https://www.teddy.lu.se/sites/teddy.lu.se/files/2021-11/55%2006032016_679_55_Sharma_PlosOne_2016.pdf - 2026-05-31

Looking back at the TEDDY study: lessons and future directions Nature Reviews Endocrinology nature reviews endocrinology https://doi.org/10.1038/s41574-024-01045-0 Review article Check for updates Looking back at the TEDDY study: lessons and future directions Åke Lernmark   1 , Daniel Agardh1, Beena Akolkar2, Patricia Gesualdo   3, William A. Hagopian4, Michael J. Haller   5, Heikki Hyöty6, Suzann

https://www.teddy.lu.se/sites/teddy.lu.se/files/2025-04/170_MP303_Lernmark_Nature%20Rev%20Endo_2024.pdf - 2026-05-31

International Marketing and Brand Management MSc in International Marketing and Brand Management LUND UNIVERSITY | SWEDEN • Master of Science with a major in Business Administration, specialisation in International Marketing and Brand Management • 1 year, full-time, 60 ECTS credits • School of Economics and Management • Lund Campus • Application deadline: January 2024 • Programme start: August 202

https://www.lunduniversity.lu.se/sites/www.lunduniversity.lu.se/files/2023-09/International-marketing-and-brand-management-factsheet-2024.pdf - 2026-05-31

International Marketing and Brand Management MSc in International Marketing and Brand Management LUND UNIVERSITY | SWEDEN • Master of Science with a major in Business Administration, specialisation in International Marketing and Brand Management • 1 year, full-time, 60 ECTS credits • School of Economics and Management • Lund Campus • Application deadline: January 2024 • Programme start: August 202

https://www.lunduniversity.lu.se/sites/www.lunduniversity.lu.se/files/2023-10/International-marketing-and-brand-management-factsheet-2024.pdf - 2026-05-31