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Human C4b-binding protein (C4BP) is a soluble, multiple-subunit inhibitor of complement that circulates in blood. Recently C4BP was shown to bind DNA, reduce DNA release from necrotic cells and limit DNA-mediated complement activation in solution. Herein we employed nuclear magnetic resonance spectroscopy to measure chemical shift perturbations and used them to restrain the computational docking o

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A searchable database of speech samples from more than 100 Swedish dialects is being established for use in research and education. Each dialect is represented by at least 12 speakers. Recordings are made of spontaneous speech as well as words and phrases elicited with a number of specific research goals in mind. This paper summarizes one of these goals, a prosodic typology for the Swedish dialect

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This paper presents a QVCO and divider for a 28 GHz SiGe PLL. It was designed in a SiGe process with fT= 200 GHz. The PLL is intended to be used for beam steering in an 81-86 GHz E-band transmitter. Phase control is implemented by programmable current injection into the loop filter. The simulations in Spectre use a layout extracted view with parasitics for the QVCO and the frequency divider and an

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I argue that Lisa Shapiro’s rational reconstruction of Descartes’s provisional moral code in terms of a broad conception of morality supplies us with an interpretative framework that make historiographical sense of the reception of Descartes’s moral philosophy in an Anglophone context on three occasions: the appeal to Descartes made by Henry More, Henry Sidgwick’s abrupt dismissal, and the ensuing

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BACKGROUND: Acrylamide, a probable human carcinogen, is formed from the amino acid asparagine and reducing sugars when potato products are processed at high temperatures. This is a two-year study on five Swedish-grown potato clones, two of which are adapted to cold storage. The clones represented a wide range of precursor concentrations: asparagine, 3.7-15.3 mg g-1; reducing sugars, 0.9-14.9 mg g-

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The objective was to evaluate a screening procedure for detecting high-yield candidates for an OGTT, in a population of middle-aged Swedish women. A two-step screening procedure was performed in 6917 subjects. Women with a positive screening outcome, i.e. increased non-fasting capillary blood glucose, serum triglycerides, BMI, WHR, blood pressure or a family history of diabetes, pharmacological tr

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The penetration of financialization into the biocultural geographies of islands builds upon processes of commodification and privatization of environments, entailing enclosures of resource commons, environmental destruction and displacement of people, their livelihoods, knowledge and practices, with implications for sustainability. Against this background I critique the growing literature on acron

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The updated Consolidated Health Economics Evaluation Reporting Standards, CHEERS 2022, is considered the most comprehensive publication to assess reporting quality of economic evaluations (EEs) incorporating criteria of trial- and model-based studies, including emerging methods. However, it holds multiple criteria per item without clear decision rules on minimum requirements for complete reporting

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Disclosed is a method (310) for providing operational feedback during power transfer in a wireless power transfer system. The wireless power transfer system comprises a power transmit device arranged to transfer power over an inductive wireless power transfer interface operating at a transmit frequency to a power receive device. The wireless power transfer system is adapted to transfer information

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Urban meteorology, the study of atmospheric phenomena in urban areas, is vital for understanding the dynamic interactions between rapid urbanization and environmental changes. Over the past two decades (2004–2024), urban heat islands (UHIs), extreme rainfall, pollution, and temperature anomalies have intensified, adversely affecting human health, infrastructure, and ecosystems worldwide. The prese

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The user-centered design or usability design or human computer interaction there are very close or similar concept, and a very wide subject of study. The Rational Unified Process is very complex by itself. There are many criticisms again The Rational Unified process because it is alleged lack of tools and helps in the user-centered development. Relating these areas by finding out the relationships

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Caenorhabditis nematodes, particularly the well-known Caenorhabditis elegans, have challenged early views of them as hard-wired by demonstrating diverse learning and memory capabilities. This cognitive repertoire, developed with just several hundred neurons, highlights the evolutionary importance of cognitive traits. In this study, we examine the relationship between learning, development, reprodu

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This paper presents a measurement of the production cross-section of a Z boson in association with b- or c-jets, in proton–proton collisions at s=13 TeV with the ATLAS experiment at the Large Hadron Collider using data corresponding to an integrated luminosity of 140 fb-1. Inclusive and differential cross-sections are measured for events containing a Z boson decaying into electrons or muons and pr

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A search is presented for the pair production of heavy vectorlike quarks (VLQs) that each decay into a W boson and a light quark. This study focuses on events where one W boson decays into leptons and the other into hadrons. The search analyzed 140 fb−1 of pp collision data with pffiffi s ¼ 13 TeV, recorded by the ATLAS detector from 2015 to 2018 during run 2 of the Large Hadron Collider. The fina

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This chapter takes an interest in the construction of gendered knowledge in the digital space. Through an analysis of the digital activism of the epistemic agent Nadia Murad, survivor of the genocide against the Yazidi, the chapter investigates how she departs from her personal, embodied experience of ISIS violence to advocate for justice, recognition and reparation. Through the methodological app

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A search for Higgs boson pair production via vector-boson fusion is performed in the Lorentz-boosted regime, where a Higgs boson candidate is reconstructed as a single large-radius jet, using 140 fb−1 of proton–proton collision data at s=13 TeV recorded by the ATLAS detector at the Large Hadron Collider. Only Higgs boson decays into bottom quark pairs are considered. The search is particularly sen

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Background: Global supply chains are confronted with the challenge of ensuring on-time deliveries while simultaneously enhancing supply chain resilience. Conventional methods aim to address the complexities of modern supply chains, promoting the transition to intelligent and data-driven strategies. Methods: This research represents an innovative methodology for predicting the risk of late deliveri

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Background: Breathlessness is common in the population and can be related to a range of medical conditions. We aimed to evaluate the burden of breathlessness related to different medical conditions in a middle-aged population. Methods: Cross-sectional analysis of the population-based Swedish CArdioPulmonary bioImage Study of adults aged 50–64 years. Breathlessness (modified Medical Research Counci