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The diagnosis of syphilis is most frequently dependent on antibody detection with serological assays. Assays for both treponemal and non-treponemal antibodies are needed to provide a sensitive and specific diagnosis. For decades, a first screening has been done with non-treponemal assays, followed by treponemal. However, in recent years, following laboratory automation, the reverse sequence screen

IgA nephropathy (IgAN) is characterized by mesangial cell proliferation and extracellular matrix expansion associated with immune deposits consisting of galactose-deficient polymeric IgA1 and C3. We have previously shown that IgA-binding regions of streptococcal M proteins colocalize with IgA in mesangial immune deposits in patients with IgAN. In the present study, the IgA-binding M4 protein from

Despite an abundance of peptides inside a cell, only a small fraction is ultimately presented by HLA-I on the cell surface. The presented peptides have HLA-I allomorph-specific motifs and are restricted in length. So far, detailed length studies have been limited to few allomorphs. Peptide-HLA-I (pHLA-I) complexes of different allomorphs are qualitatively and quantitatively influenced by tapasin t

Some concerns still have not been resolved about the long-term safety of drug-eluting stents (DES) in patients with acute STEMI.

Complement components and their cascade of reactions are important defense mechanisms within both innate and adaptive immunity. Many complement deficient patients still remain undiagnosed because of a lack of high throughput screening tools. Aiming towards neonatal proteome screening for immunodeficiencies, we used a multiplex profiling approach with antibody bead arrays to measure 9 complement pr

During sexual conflict, males and females are expected to evolve traits and behaviours with a sexually antagonistic function. Recently, sexually antagonistic coevolution was proposed to occur between male and female diving beetles (Dytiscidae). Male diving beetles possess numerous suction cups on their forelegs whereas females commonly have rough structures on their elytra. These rough structures

Popular Abstract in Swedish Under de senaste decennierna har det pågått en intensiv kamp om dramapedagogikens innehåll. Den har i betydande utsträckning förts på nordiskt plan. Dramaläraren och lärarutbildaren Viveka Rasmusson visar att denna debatt om dramaämnet och dess utveckling med fördel kan studeras i den nordiska tidskriften Drama. Under större delen av sjuttiotalet var Drama ett gemensamtBased on the Nordic dramapedagogic journal Drama during the period 1965-1995 the thesis analyses Nordic dramapedagogy and the dramatheoretical debate of the subject drama, which entered Nordic school curriculums in the sixties and the seventies. During the period a struggle was fought by predecessors from different aestethic and pedagogical directions concerning the definition of the subject. The

Vid den nordiska konferensen ”Teaching bioethics” illustrerade transplantationskirurgen Nils H. Persson och jag hur en dialogpedagogisk metod kan belysa en frågeställning på ett sätt som är svårt för en ensam lärare. Nils H. Persson diskuterade bland annat den stora skillnaden i frekvens av organdonationer mellan de nordiska länderna, mindre än 15 PMP (per million population), och Spanien, mer än

In this paper, tone mapping operations based on the nonlinear successive Mean Quantization Transform (SMQT) are proposed in order to convert high dynamic range images to low dynamic range images. A SMQTbased tone mapping applied on the luminance channel is derived as well as a SMQT-based method working directly on all RGB channels. Both methods are compared to other state-of-the-art methods and pr

We have in this study analyzed the function of the murine Joining chain (J chain) in vivo. J chain is a polypeptide found in sera and secretions in complex with pentameric IgM and dimeric IgA. J chain is expressed in terminally differentiated B lymphocytes and needed for the transport of dimeric IgA and pentameric IgM over mucosal surfaces via the poly Ig receptor. A mouse deficient for J chain wa

This article outlines an experimental and numerical study of the long-term interaction between silica fume and Portland cement in concrete subjected to air, water or sealed curing. For this purpose about 2000 kg of eight qualities of concrete were studied at 4 different ages each over a period of 90 months. Half of the concretes contained silica fume. Parallel studies of strength, hydration and in

The article explores influences from Old Testament and Gnostic sources upon Japanese video game culture and also discusses the relationship between the player and the played in said games - from a perspective rooted in an exegesis of such texts. It also concerns the pop-culture climate of the 1990s and early 2000s in this context.

Wave cycle distributions are notoriously difficult to calculate. Available analytic approximations, like those suggested by Longuet-Higgins (1983) and Cavanie, Arhan and Ezraty (1976) make use only of a few spectral moments, and are unreliable for moderate waves. To find distributions under general spectrum shape and parameters one has to use efficient numerical algorithms based on high-dimensiona

The World Wide Web is undoubtedly very successful. Despite that, limitations have been recognized. The basic limiting factor is that the Web handles document for humans to read but not data and information for computers to read. The remedy of this is to provide the Web with semantics: the Semantic Web. While I agree that there is a need for another organization in which it is easier to find the in