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Product innovation in highly complex and technological areas, such as medical technology, puts high requirements on innovation capability of an organization. Previous research and publications have highlighted organizational issues and learning matters as important and necessary for the development of innovation capability. Action learning require reflections of the ways things are carried out, ch

Complement offers a first line of defence against infection through the opsonization of microbial pathogens, recruitment of professional phagocytes to the infection site and the coordination of inflammatory responses required for the resolution of infection. Staphylococcus aureus is a successful pathogen that has developed multiple mechanisms to thwart host immune responses. Understanding the prec

We revisit the abundances of neutron-capture elements in the metal-poor ([Fe/H] = -2.9) r-process-rich halo star CS 31082-001. Partly motivated by the development of the new near-ultraviolet Cassegrain U-band Efficient Spectrograph for the Very Large Telescope, we compiled an expanded line list for heavy elements over the range 3000-4000 Å, including hyperfine structure for several elements. Combi

Epithelioid and spindle cell hemangioma was initially described in 1999 in a series of primary bone tumors and was subsequently suggested by some to represent a variant of epithelioid hemangioma. Here, we studied 18 epithelioid and spindle cell hemangiomas. Nine patients (50%) were male. Age at presentation ranged from 12 to 78 years (median: 38.5 y). Nine patients (50%) had tumor(s) limited to bo

With the construction sector being responsible for about 40% of the energy and material use, the sector has a great responsibility for lowering the consumption if we are to succeed in our global pursuit for the green transition. However, buildings must still comply with the demands of users. For long-span, openspace lightweight, multi-storey buildings, this provides a potential risk related to ann

As part of the green transition, a current trend in the construction sector is to utilize more wood and lightweight composites, aiming at a reduction of the embodied energy in buildings. At the same time, with a focus on circularity and reuse, large-span structures are preferable, since they provide more flexibility for future uses of the building. The mix of large spans and lightweight structures

Timber buildings are intrinsically lightweight and hence can be susceptible to low-frequency vibrations and structure-borne noise. So, within the development of technical solutions for mitigating unwanted vibrations and noise, accurate and computationally efficient numerical models are considered to be of great value. Such models should take into account all physical phenomena that are relevant fo

We present an upgraded version of the mocca code for the study of dynamical evolution of globular clusters (GCs) and its first application to the study of evolution of multiple stellar populations. We explore initial conditions spanning different structural parameters for the first (FG) and second generation of stars (SG) and we analyse their effect on the binary dynamics and survival. Here, we fo

Presents a new view of the standard of living development in Sweden during the agricultural revolution, using evidence on the ability to overcome short-term economic stress. The results corroborate previous findings, based on a variety of indicators, that standard of living in Sweden increased for most people after the mid-nineteenth century, but also support a more negative view of the immediate

Lymphoid organ hypertrophy is a characteristic feature of acute infection and is considered to enable efficient induction of adaptive immune responses. Accordingly, oral infection with rotavirus induced a robust increase in cellularity in the mesenteric LNs, whose kinetics correlated with viral load and was caused by halted lymphocyte egress and increased recruitment of cells without altered cellu

This chapter examines changes to safe third country law and practice from 2010 to 2020 focusing on Europe, Australia, North, and South America. These developments have received little academic attention, particularly from a comparative perspective. We argue that in all four regions there has been a significant weakening of protection standards in the safe third country context, with the thresholds

Slow- and non-growing bacterial populations, along with intracellular pathogens, often evade standard antibacterial treatments and are linked to persistent and recurrent infections. This necessitates the development of therapies specifically targeting nonproliferating bacteria. To identify compounds active against non-growing uropathogenic Escherichia coli (UPEC) we performed a drug-repurposing sc

Persistent bacterial airway infection is a hallmark feature of cystic fibrosis (CF). Achromobacter spp. are gram-negative rods that can cause persistent airway infection in people with CF (pwCF), but the knowledge of host immune responses to these bacteria is limited. The aim of this study was to investigate if patients develop antibodies against Achromobacter xylosoxidans, the most common Achromo

The chapter is concerned with simultaneous bilinguals (2L1s) assuming that they are a subtype of the heritage speaker (HS). The chapter summarizes major findings with regard to their morpho-syntactic and phonological characteristics, starting with the two competing views on bilingual language development that postulated fused language systems as opposed to autonomous development several decades ag

Background: High gluten and low dietary fiber in pregnancy intake is associated with an increased risk of celiac disease (CeD) in the child. Early life higher dietary quality is suggested to reduce the subsequent risk of CeD. Objectives: The aim was to investigate associations of pregnancy dietary quality and diversity with child risk of CeD. Methods: In The Norwegian Mother, Father and Child Coho

Background: The affective profiles model, operationalized as the combination of individuals’ high/low positive/negative affective experience, is a well-established method for providing insights into adolescents’ affective functioning and self-regulation: self-fulfilling (high positive affect, low negative affect), high affective (high positive affect, high negative affect), low affective (low posi