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Parkinson’s disease (PD) is a movement disorder of the brain which is hallmarked by the presence of large protein-rich cytoplasmic aggregates, called Lewy bodies (LBs), in the neurons. The protein α-synuclein (α-syn) is abundant in these aggregates, and can itself form aggregates. Several mutations linked to α-syn are also linked to an increased risk of contracting PD. In healthy neurons, the chap
The study aims to uncover the discursive elements at work in Swedish public discourse on antisemitism. The study situates the International Holocaust Remembrance Alliance definition of antisemitism in relation to Swedish discourse with the aim of measuring their congruence. A final aim is to uncover if the broadening of the term has led to marginalisation of those seen as problematic – constitutiv
Pyruvate is one of the main molecules needed for the citric acid cycle, which produces energy in the form of ATP. The citric acid cycle reaction occurs in the mitochondrial matrix, and for pyruvate to participate in the reaction, it needs to be transported from the cytosol across the mitochondrial membranes into the mitochondrial matrix. A special membrane protein called the mitochondrial pyruvate
The age structure and its impact on economic growth is a current issue that concerns all countries in the world. For Sri Lanka, the issue lies within an ageing population and the economic implications of the growing share of elderly. Thus, this paper strives to investigate how the age structure in Sri Lanka affects the economic growth, mainly looking at the ageing population. A time series regress
Under den senaste tiden, har försörjningskedjan för livsmedel genomgått stora förändringar när det gäller strukturen av marknaden. Många faktorer har påverkat denna utveckling, till exempel ändrade preferenser hos konsumenterna, möjligheterna till internationell handel, administrativa krav och handels egna varumärken. Denna utveckling har medfört en obalans av marknadsmakt. Återförsäljarna har mycRecently, the food supply chain and especially the grocery retail sector has been subject to a significant change in relationship structure. The retail sector has become increasingly concentrated. Many factors have contributed to this development, including changes in consumer preferences, the facilitation of cross-border trade, administrative requirements and local zoning laws and the popularity
The spread of pathogens between individuals has important effects on patterns of mortality, behaviour and the genetic structure of populations. One factor that is predicted to influence the transmission of pathogens is the genetic diversity of the host group. Groups of closely related individuals are susceptible to similar pathogens, and hence increase in genetic diversity of the group should decr
Background Axis is a network surveillance company, based in Lund, Sweden. Axis has outsourced its production to contract manufacturers which are positioned in different parts of the world. Axis’ suppliers are also spread across the globe. During the last years, Axis has experienced several supply disruptions from its suppliers and contract manufacturers, due to natural and technological disasters.
In December 2001, Martin Creed received the Turner Prize for his artwork Work No. 227: The lights going on and off (2000). A minimalist light installation, simplistic in its effectuation, yet complicated enough to hold questions about what art is and what role the institution plays in valuing and validating art. The purpose of this thesis is to conduct an investigation of critiques in newspaper ar
With sustainability at the forefront of many cities’ urban development plans, it is possible that sustainable polices are targeted to attract a certain group of inhabitants. Malmö, Sweden, has implemented changes in order to gain international recognition as a green city but has also been experiencing growing residential segregation. The presence of urban greening projects is a keystone to human h
The increased capacity of elementary particle accelerators raises the demand for the simulation data of the experiments. One of the bottlenecks in the simulations is the QCD color structure calculation, which is usually treated using non-orthogonal and overcomplete sets of bases. The computational cost could be decreased significantly if orthogonal bases, such as the multiplet bases, were used ins
The goal of this thesis is to construct p-harmonic functions on the Lie groups U(n), SU(n), U(p,q) and SU(p,q) equipped with the semi-Riemannian metric g(Z,W) = Re trace ( Z W^t ). To do this we present a method which relies on the notion of eigenfunctions. We define these functions and find examples of them defined on the relevant groups. To our knowledge, these eigenfunctions have not been p
Fibrosis is a process characterized by the accumulation of extracellular matrix components and is attributed to excessive scar formation and is a common feature of many chronic inflammatory conditions. Fibrogenesis involves multiple inflammatory cells including NKT cells, which have been suggested to play a prominent role in the control of this process. Here we characterize a transgenic mouse mode
Plant-insect interactions play a crucial role in the evolution of the coevolving web of life, shaping local interaction networks and moulding the diversity and the evolutionary history of two of the most diverse groups of organisms on earth. The interaction between Lithophragma bolanderi (Saxifragaceae), which presents a geographic mosaic of ploidy levels, and the pollinating floral parasite Greya
This study compares the performance of equal- and value-weighted portfolios using a broad investment universe consisting of the stocks from the Swedish stock market. While implementing random sampling in the portfolio construction procedure, three rebalancing schemes are applied on the equally weighted portfolio in order to observe differences in performance among these. In order to compare how mu
Like many things, social movements have been able to take a new form, and behave differently, thanks to the rise of the internet and social media networks. The purpose of this study is to analyze how long lasting this engagement is from its participants, and how short-run participation in social movements can be understood. This study has been heavily inspired by Zizi Papacharissi, therefore the t
Inclusive innovation is seen as a means to counteract the issue of growing global inequality. Particularly universities and private businesses are engaged with its promotion. However, the concept of inclusive innovation has deficiencies concerning the operationalisation and measurement. In default of extensive primary data, a set of a hundred and two inclusive innovations has been gathered from tw
This study analyzes the relationship between education, antibiotic consumption and antibiotic resistance in the European ambulatory care. For this purpose, a panel data analysis is conducted on an aggregate level in a sample of 30 countries in the European Economic Area between 2000 and 2014. The main variable of interest is the level of high education, expressed as the proportion of the total pop
