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Satellite remote sensing is a powerful tool for modelling gross primary production (GPP) at large scales. While model comparison is a prerequisite for understanding carbon dynamics comprehensively, existing GPP products rely on a limited number of satellite sensors. In this study, the contemporary fraction of absorbed photosynthetically active radiation product derived from PROBA-V and Sentinel-3
Introduction: Side-stream residue, oat okara, from the oat-milk production contains valuable nutrients but possesses a high risk of microbial spoilage. Valorisation of oat okara is therefore important to make sure that the oat beverage production stays sustainable. In this project, High-pressure processing (HPP), heat treatment and Lactobacillus fermentation have been evaluated for their microbial
Médecins Sans Frontières (MSF) does currently not have dedicated decision-making support for their in-country inventory allocation and is exploring how such decision support framework could be designed to enhance their supply chain operations. The purpose of this thesis is thus to develop a structured framework for country-level inventory allocation decision-making at MSF.To fulfil the purpose t
The selective separation of glycoproteins is essential in biomarker discovery, glycoprotein profiling and analysis. Glycosylation of proteins has a major impact on their structure and function. The heterogeneity of glycosylation patterns makes the glycomic profiling extensive, but nonetheless of upmost importance for the deeper understanding of metabolic pathways, cell signalling and the impact of
Solanum tuberosum (Potato) is a cool-season, short-day crop that tuberize effectively at temperatures between 15°C-19°C and at a day length of about 12 hours. These environmental requirements pose a moderate challenge to potato cultivar in different region globally. In Northern Europe, summers are characterized by the prolonged daylight and temperature that frequently exceed 19℃. Such conditions c
With the rapid evolution of semiconductor technology and the growing demand for high-performance, low-power System-on-Chip solutions, the design of efficient and scalable on-chip interconnect architectures has become a critical challenge in modern ASIC development. This thesis focuses on design space exploration of replacing multiple ARM CoreLink NIC-400 crossbar-based interconnects with a unified
The recent years spread of misinformation and the rise of post-truth politics have challenged the role of public service media in democratic societies. This thesis explores how the Nordic public service broadcasters – SVT, NRK, DR, RÚV and Yle – position themselves in relation to disinformation, misinformation, and post-truth. Through a qualitative, thematic analysis of their annual reports from 2
Geographical peripheries have long faced marginalization and degradation, enhanced by global trends such as urbanisation. Recently, their revitalization has gained urgency within sustainability discourse, seen as key to achieving global sustainable development. Yet, interventions often focus narrowly on economic recovery, overlooking the social dimension, particularly social cohesion, which is ess
The purpose of this thesis is to enrich our understanding of micro-level internal legal culture by examining how Indonesian legislative lawyers navigate tensions between legal principles and political pressures. The focus is on civil servants within the Coordinating Ministry for Human Development and Cultural Affairs who are tasked with law-making processes, such as drafting, negotiating, and
AI-genererade verk har ökat snabbt under det senaste årtiondet och skakat om EU:s immaterialrättsliga landskap. Tack vare dessa intelligenta system kan individer idag skapa verk som överträffar mänskligt hantverk på bara några minuter. Verk som utnyttjar AI, särskilt autonoma produkter, utmanar de trad-itionella uppfattningar som upphovsrättslagstiftningen bygger på. Frågan om dessa verk kan erhål
Materialvariation i gråjärn diskuteras vanligtvis utifrån metallurgi eller bearbetbarhet, medan dess konsekvenser för produktionsflödet och styckkostnaden är mindre systematiskt karaktäriserade. Detta examensarbete undersöker hur sammansättningsvariation i gråjärn propagerar genom bearbetningsrespons till produktionssystemets beteende, och kvantifierar de resulterande ekonomiska konsekvenserna perMaterial variability in grey cast iron is usually discussed in terms of metallurgy or machinability, while its consequences for production-flow behaviour and per-part economics are less systematically characterised. This thesis investigates how compositional variability in grey cast iron propagates through machining response into production-system behaviour, and quantifies the resulting per-part e
Small interfering RNAs (siRNAs) are a rapidly growing class of oligonucleotide therapeutics that modulate gene expression by inducing targeted mRNA degradation. siRNAs are potent and their effect is long-lasting, making them promising candidates for chronic neurodegenerative disease. However, siRNAs can elicit both on- and off-target toxicity, and while acute neurotoxicity has been characterized,
Early diagnosis of colorectal cancer (CRC) is crucial for successful treatment and mortality reduction. In this regard, blood-based tests play an indispensable role. Current research is focused on molecules actively secreted by tumor cells into small extracellular vesicles (EVs). This four-phase study included 613 CRC patients, 446 controls, and 120 precancerous lesions. High-throughput transcript
Background: Congenital heart disease (CHD) is the most common organ anomaly in humans affecting approximately 1:125 newborns worldwide. Early diagnosis enables postnatal stabilisation and may improve outcomes, especially in critical CHD, in which the circulation is dependent on patency of the arterial duct. Detection of CHD in newborns remains incomplete and current screening programs do not aim t
Recent studies have demonstrated that the transcription factor hepatocyte nuclear factor 4α (HNF4A) drives epithelial differentiation in the renal proximal tubules (PTs) and is critical for maintaining a mature PT phenotype. Furthermore, HNF4A down-regulation has been observed following kidney injury in mouse models. The aim of the present work was to investigate the role of HNF4A during acute and
One of the key purposes of bone tissue engineering is the development of new biomaterials that can stimulate the body's own regenerative mechanism for patient's anatomical and functional recovery. Bioactive glasses, due to their versatile properties, are excellent candidates to fabricate porous 3-D architectures for bone replacement. In this work, morphological and structural investigations are ca
The Gaussian phase distribution approximation enables analysis of restricted diffusion encoded by general gradient waveforms but fails to account for the diffraction-like features that may occur for simple pore geometries. We investigate the range of validity of the approximation by random walk simulations of restricted diffusion in a cylinder using isotropic diffusion encoding sequences as well a
A search for long-lived particles (LLPs) using Formula Presented of Formula Presented collision data with Formula Presented recorded by the ATLAS experiment at the LHC is presented. The search targets LLPs with masses between 5 and 55 GeV that decay hadronically in the ATLAS inner detector. Benchmark models with LLP pair production from exotic decays of the Higgs boson and models featuring long-li
Although many efforts have been made to eliminate barriers in public transport worldwide, research shows that public transport is still often perceived as challenging, inconvenient, and inaccessible for many people with disabilities. A growing body of research points to several issues, relating to the spatial and temporal distribution of public transport, affordability, safety, and social barriers
BACKGROUND: Selective glomerular hypofiltration syndrome (SGHS), formerly shrunken pore syndrome, an emerging marker of glomerular dysfunction, is associated with worsened prognosis in cardiovascular disease, but its role in kidney failure remains underexplored. Osteopontin (OPN) is associated with worsening kidney function and prognosis in chronic kidney disease.PURPOSE: To explore if increased l
