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Introduction: Immune checkpoint inhibitors (ICIs) have transformed lung cancer treatment, yet their effectiveness seem restricted to certain patient subsets. Current clinical stratification on the basis of programmed death ligand 1 (PD-L1) expression offers limited predictive value. Given the mechanism of action, directly detecting spatial programmed cell death protein 1 (PD1)–PD-L1 interactions m
Community-acquired pneumonia (CAP) is a significant health threat for adults. Although conjugate vaccines have reduced pneumococcal CAP incidence in children, Streptococcus pneumoniae-related CAP remains prevalent among older adults. The nasopharynx acts as a reservoir for S. pneumoniae, yet the interplay between this pathogen and the nasopharyngeal microbiome during and after pneumonia remains po
ObjectivesThis nested case–control study aimed to investigate the relationship between components of the Swedish food-based dietary guidelines (SDG) from 2015 and the risk of developing rheumatoid arthritis (RA).MethodsData were obtained from the prospective Malmö Diet and Cancer Study (MDCS) conducted 1991–1996. Diet was assessed at baseline using a validated diet history method. Incident RA case
The central theme of this thesis is anthropogenic climate change; governments' inability to create an effective, inclusive response mechanism that manages to mitigate anthropogenic emissions; and advocates efforts to coerce States to act by invoking State responsibility in adjudicatory dispute settlement processes. States' failure to act in accordance with scientific risk assessments and
Agonism against the odds Epistemic disruptions and bodies of dissent in Palestine and Israel ANNE LENE STEIN DEPARTMENT OF POLITICAL SCIENCE | LUND UNIVERSITY Faculty of Social Sciences Department of Political Science Lund Political Studies 225 ISBN 978-91-8104-537-6 ISSN 0460-0037 This thesis explores how protests and performances in Palestine and Israel are used to challenge dominant versions of
Uppdaterad sommaren 2021 Studentguide 1 VÄLKOMMEN TILL LOGOPEDPROGRAMMET VID LUNDS UNIVERSITET Lunds universitet grundades 1666 och i dag studerar ca 42 000 studenter på grundläggande och avancerad nivå. Universitetet har ca 3300 forskarstuderande och 7600 anställda. Det är med andra ord ett stort universitet som hälsar dig välkommen! Universitetet är indelat i ett antal områden, så kallade fakult
https://www.student.med.lu.se/sites/student.med.lu.se/files/2021-06/Studentguide_logoped.pdf - 2026-07-17
This thesis explores current trends in social and political organising in Northern Syria, in areas controlled by the PYD. The research is built on discussions between eight participants from the Syrian Kurdish-speaking community living in the areas. While most discourses on Syria and the Kurdish-speaking community have a macro-political focus and produce racialising descriptions of “Kurdishness” i
Syftet med denna uppsats har varit att utvärdera effekten av korttidsfamiljebehandling med fokus på förändringar i familjens känslomässiga klimat och förändringar av symtom hos det barn som är identifierad patient. Arbetet utgick från frågorna: Hur förändras upplevelsen hos de olika familjemedlemmarna avseende familjens känslomässiga klimat? Upplever barnet en symtomminskning? Upplever föräldrarnaThe purpose of this paper was to evaluate the effect of a short-term family treatment regarding changes in the family's emotional climate and changes in the symptoms of the child. The work was based on the questions: How does family members experience the family's emotional climate? Does the child experience a decrease in symptoms? Do the parents experience a decrease in the symptoms of th
The impact of plastic on the environment has been acknowledged on different levels, among others various NGOs around the world. These NGOs are known to aim for a reduction of plastic ending up in nature and more specifically the ocean. Plastic has been instrumental to the development of modern societies since the 1950s as the properties of the material enables it to be used for various purposes. T
OBJECTIVE- Some individuals with normal glucose tolerance (NGT) exhibit a 1-h excursion of plasma glucose during oral glucose tolerance testing as high as that of individuals with impaired glucose tolerance (IGT). The aim of this study was to characterize their metabolic phenotype. RESEARCH DESIGN AND METHODS- A total of 1,205 healthy volunteers (aged 29-61 years) underwent assessment of 1) oral g
Cassava cultivars are classified following different criteria, such as cyanogenic glucoside content or starch content. Here, flours from the roots of 25 cassava varieties cultivated simultaneously in a single plantation, were characterized in terms of starch content (SC), amylose content (AC), alpha-amylolysis index (AI) and gel formation ability. Resistant starch content (RS) was measured in 10 o
Karyotype structures of Scenedesmus acuminatus (Lagerch.) Chod. and Scenedesmus pectinatus Meyen are compared. The karyotype of S. acuminatus (n = 5) is described for the first time. It reveals four large metacentric and one large submeta centric chromosomes (4M + 1SM). The established karyotype differences have been helpful in clarifying the taxonomic position of these two species. The cytologica
Moraxella catarrhalis ubiquitous surface protein A2 (UspA2) mediates resistance to the bactericidal activity of normal human serum. In this study, an interaction between the complement fluid phase regulator of the classical pathway, C4b binding protein (C4BP), and M. catarrhalis mutants lacking UspA1 and/or UspA2 was analyzed by flow cytometry and a RIA. Two clinical isolates of M. catarrhalis exp
More and more people are moving to cities all over the world, to look for better educational or employment opportunities as well as take advantage of social benefits and technological network by the cities. Rapidly increasing urbanisation and climate change are creating new challenges for cities to undertake, which is where many cities turn to implementing the smart city concept. The purpose of th
AimsSocial participation is an important determinant of health-related behaviours and health. Communication disorders such as stuttering may be associated with participation. Research concerning the association between stuttering and social participation among older adults is scarce. Therefore, the aim of this population-based cross-sectional study was to investigate associations between self-perc
