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Popular Abstract in Swedish Bakgrund I Sverige erbjuds samtliga gravida kvinnor ett rutinultraljud vid 18-20 graviditetsveckor. Syftet med undersökningen är att fastställa antalet foster, uppskatta graviditetslängd samt granska fosteranatomin för att upptäcka eventuella missbildningar. En del missbildningar kan man se med ultraljud, men långtifrån alla. Att redan under graviditeten känna till om The aim was to evaluate first trimester nuchal translucency (NT) measurement for detection and risk assessment of fetal malformations and fetal loss. 39 572 pregnant women were randomised to either a routine ultrasound scan at 12-14 weeks including NT measurement or to a routine scan at 18-20 weeks. Prenatal diagnosis of major congenital heart malformations was compared between the two groups. In

OBJECTIVES: To explore the possibility that a paleolithic-like diet can be used in the prevention of age-related degenerative Western disease. METHODS: Literature review of African Paleolithic foods in relation to recent evidence of healthy nutrition. RESULTS AND DISCUSSION: Available evidence lends weak support in favor and little against the notion that lean meat, fish, vegetables, tubers, and f

Complement is a key arm of the innate immune defenses against the pathogenic neisseriae. We previously identified lipooligosaccharide on Neisseria meningitidis as an acceptor for complement C4b. Little is known about other neisserial targets for complement proteins C3 and C4, which covalently attach to bacterial surfaces and initiate opsonization and killing. In this study we demonstrate that N. g

A stratified viscoelastic medium in the time domain is characterised by two creep compliances that are functions of time and depth, and a density that is a function of depth. In this paper the direct scattering problem of a plane horizontal shear wave obliquely incident on a stratified viscoelastic medium is treated in detail. A general discussion of the corresponding inverse problem is given. A s

Several new oral antidiabetic agents, known as 'gliptins' or 'enzyme dipeptidyl peptidase-IV (DPP-4) inhibitors', have been developed for the treatment of type 2 diabetes and a key clinical use of the gliptins is in combination with metformin. There are important differences in the kinetics of the interaction of different gliptins with the catalytic site of DPP-4, which may lead to varying pharmac

Accumulating evidence implicates a role for altered metal homeostasis in the pathogenesis of neurodegenerative disorders such as Alzheimer's disease (AD). However, few investigations have addressed this issue in dementia with Lewy bodies (DLB). The aim of the present study was to investigate metal concentrations in cerebrospinal fluid (CSF) and plasma from patients with DLB and other neurodegenera

In a recent paper, Cetinkaya and Lee (2000) model integrated inventory control and shipment scheduling in connection with vendor-managed inventory (VMI). The model is optimized by an approximate technique. This note provides a simple procedure for exact optimization, and illustrates that the errors when using the suggested approximate technique may be very large for certain types of problems. We a

A previous caesarean delivery is no longer an indication per se for a subsequent, planned caesarean. We performed this study to identify women suitable for trial of labour after caesarean (TOLAC), investigating the association between the indication for the first caesarean and the risk of unplanned caesarean in the second pregnancy.

Abstract BACKGROUND: Family history has been suggested as a risk factor for varicose veins, but recall bias may inflate the familial risks. The aim of this nationwide study was to determine familial risks for hospital treatment for varicose veins. METHODS: Data from the Swedish Multi-Generation Register of people aged 0-76 years were linked to Hospital Discharge Register data for 1964-2008. Stand

Recombinant lentiviral vectors (rLV) are powerful tools for gene transfer to the central nervous system (CNS) and hold great potential as a therapeutic gene therapy strategy for neurological disorders. Recent data indicate that rLVs are suitable for functional studies in the CNS by over expression or knock down of specific proteins. Based on a variety of lentiviruses species, different vector syst

A shorted pin circular axe-shaped antenna is analyzed for compact and dual band applications. Removing two symmetric arc-shaped areas from a simple circular patch lengthens the current path thus reduces the antenna size. Embedding and adjusting a shorting pin further shifts the resonance to a lower frequency and excites another high order mode. The frequency ratio varies between 1.639 ∼ 2.616. The

PalCom is a pervasive middleware that can be used to assemble services provided by networked devices into configurations, called assemblies, for specific use cases by the user. In this dissertation, we present the development of a networking media abstraction framework for PalCom that abstracts different network interfaces in a PalCom device to upper layers of PalCom. The media abstraction framewo

Breast cancer is the most common cancer among women worldwide, although the mortality rates have decreased in the last decades. Breast cancer is a heterogeneous disease, and treatment resistance is a significant clinical problem in spite of the overall high survival rates. Improved screening programs, novel surgical techniques, and adjuvant treatments have contributed to the improved survival,

Environmental research infrastructures (RIs) support their respective research communities by integrating large-scale sensor/observation networks with data curation services, analytical tools and common operational policies. These RIs are developed as pillars of intra-and interdisciplinary research, however comprehension of the complex, pathologically interconnected aspects of the Earth's ecosyste

A promising approach for addressing sustainability problems is to recognize the unique conditions of a particular place, such as problem features and solution capabilities, and adopt and adapt solutions developed at other places around the world. Therefore, research and teaching in international networks becomes critical, as it allows for accelerating learning by sharing problem understandings, su

Background It has been proposed that cancer is more common in some families than in others, but the hypothesis lacks population level support. We use a novel approach by studying any cancers in large threegeneration families and thus are able to find risks even though penetrance is low. Methods Individuals in the nation-wide Swedish Family- Cancer Database were organised in three generations and t

Peatland net ecosystem production is a key variable to assess changes in the functional role of peatlands in the global carbon cycle. Light use efficiency (LUE) models in combination with satellite data have been used to estimate production for most major ecosystems, but peatlands have been largely ignored. The objectives of this study were: 1) to examine how the LUE parameter epsilon, ε (the amou