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Influence of family history on risk of second primary cancers and survival in patients with squamous cell skin cancer

Background: Patients with squamous cell skin cancer (SCC) have an excellent prognosis but second primary cancers (SPCs) weaken survival prospects. Family history is a known risk factor for cancer but whether it is a risk factor for SPC in patients with SCC is not known. Objectives: To quantify the risk of family history on SPCs in patients with SCC and estimate survival probabilities of patients w

Oncoplastic Breast Surgery Compared to Conventional Breast-Conserving Surgery With Regard to Oncologic Outcome

Introduction: Oncoplastic breast surgery (OBS) has been implemented with increasing frequency in the treatment of breast cancer. The aim of this study was to compare the oncologic outcome after OBS to the outcome after conventional breast-conserving surgery (BCS) in patients with invasive breast cancer. Patients and Methods: In all, 197 patients treated with OBS were compared to 1399 patients trea

Publications2021jan

Header 1 2021-01-25 1 Peer reviewed publications (data and/or co-authors at the national 7T facility) [1] [1-29] 1. Novén, M., Schremm, A., Horne, M., Roll, M., Cortical thickness and surface area of left anterior temporal areas affects processing of phonological cues to morphosyntax, Brain Research 2021,1750:147150 2. Wiggermann, V., Mackay, A. L., Rauscher, A., Helms, G., In vivo investigation o

https://www.lbic.lu.se/sites/lbic.lu.se/files/publications2021jan.pdf - 2026-05-30

Multi-agent AI enables evidence-based cell annotation in single-cell transcriptomics

Cell type annotation remains a critical bottleneck, with current methods often inaccurate and requiring extensive manual validation, particularly in disease contexts. While large language models (LLMs) show promise, they can be unreliable due to hallucinations. We developed CyteType, a multi-agent framework that generates competing hypotheses grounded in full expression data and study context, val

Insights from Single-cell Omics - Cellular Heterogeneity as a Foundation of Clinical Outcome in Chronic Myeloid Leukemia

The BCR::ABL1 tyrosine kinase inhibitors (TKIs) in CML represent a paradigm for molecularly targeted therapy. However, clinical outcomes - rate/depth of response, treatment-free remission (TFR), progression to blast crisis (BC) - and adverse events vary among patients. While additional somatic mutations have been invoked to explain varying clinical outcomes, we here propose a complementary perspec

Mdc vital cancer endpoint report 2017

The Malmö Diet and Cancer Study The Malmö Diet and Cancer Study Department of Clinical Sciences Skåne University Hospital, Malmö Lund University The Malmö Diet and Cancer Study The EPIC cohort Vital Status – Cancer Endpoints End of follow-up: 31 December 2016 Report: 16 November 2017 1. Cohort 2. Lost to follow-up 3. Vital status 4. Time of follow-up 5. Cause-of-death 6. Cancer endpoints Anders Da

https://www.malmo-kohorter.lu.se/sites/malmo-kohorter.lu.se/files/mdc_vital_cancer_endpoint_report_2017.pdf - 2026-05-30

Family history of venous thromboembolism as a risk factor and genetic research tool.

Familial clustering of venous thromboembolism (VTE) was described as far back as 1905 by Briggs. Although Egeberg discovered inherited deficiency of antithrombin in 1965, it was not until Dahlbäck discovered resistance to activated protein C in 1993 that it became clear that genetic factors are common risk factors of VTE. Several genes have been linked to familial aggregation of VTE and genome-wid

Risk of ocular manifestations in patients with giant cell arteritis : a nationwide study in Sweden

Objective: No large-scale nationwide study has determined the risk of ocular manifestations in patients with giant cell arteritis (GCA). The aim was to study the incidence and risk factors of ocular manifestations in patients with GCA in Sweden. Method: A national cohort was created by linking Swedish nationwide registers. GCA patients were identified from the Swedish Hospital Inpatient and Outpat

DNA sample cleanup using deterministic lateral displacement

Optical mapping relies on the preparation of fluorescent DNA. DNA must be imaged with good signal to noise and therefore the background of unwanted DNA fragments, fluorescent dyes and other reagents need to be removed. We use deterministic lateral displacement to separate 48.5 kbp DNA from < 10 kbp DNA. We also show the removal of 48.5 kbp DNA fragments from a background of fluorescent ATTO647N mo

Reimagining the Capitalocentric Present : Unpacking Fantasies of Ethical Consumption: Introducing new Consumer Ethics, and Establishing Sustainable Visions

In this conceptual paper we reimagine the Capitalocentric present. To do so, we (1) critique corporate fantasies about ethical consumption; (2) offer alternative relational ethics of consumption, with special attention to concrete neo-animist practices to imagine alternative futures to the Capitalocentric present, and (3) invite imaginative theorization as a bridge between present and future.In this conceptual paper we reimagine the Capitalocentric present. To do so, we (1) critique corporate fantasies about ethical consumption; (2) offer alternative relational ethics of consumption, with special attention to concrete neo-animist practices to imagine alternative futures to the Capitalocentric present, and (3) invite imaginative theorization as a bridge between present and future.

Thrombomodulin gene c.1418C>T polymorphism and risk of recurrent venous thromboembolism.

Thrombomodulin gene (THBD) is a critical cofactor in protein C anticoagulant system. THBD c.1418C>T polymorphism is reported to be associated with higher risk of primary venous thromboembolism (VTE) but its role in VTE recurrence is unknown. The aim of this study was to investigate the role of THBD polymorphism in VTE recurrence. THBD c.1418C>T polymorphism was genotyped by using Taqman polymerase

From Intensification to Sustainability? Political Leadership and Agricultural Transformation in Ethiopia

Ethiopia achieved a remarkable episode of agricultural intensification from the mid-1990s to the late-2010s, yet the political mechanisms that enabled this transformation—and the distributional and environmental consequences that followed—remain insufficiently understood. This article ex- amines how political leadership, understood in institutional rather than personalistic terms, shaped both the Ethiopia achieved a remarkable episode of agricultural intensification from the mid-1990s to the late-2010s, yet the political mechanisms that enabled this transformation—and the distributional and environmental consequences that followed—remain insufficiently understood. This article ex- amines how political leadership, understood in institutional rather than personalistic terms, shaped both the

Elevated psychiatric and substance use disorders in people with intellectual disabilities in a Swedish National Sample

Background. Adults with intellectual disability (ID) experience marked mental health inequities, yet population-wide estimates that capture both primary- and specialist-care diagnoses remain scarce. Methods. Using nationwide Swedish registries, including primary care, specialist, inpatient, prescription drug, criminal, and suspicion registers, we included all individuals born in Sweden between 195

Soch-infoblad-2016-06-16

Prefekten informerar • Nyheter på medarbetarfronten. Anette Salling, Frans Oddner, Lars Norén och Inari Johansson lämnar oss under sommaren. Stort tack för era insatser de år ni arbetade för oss. I skrivande stund har det blivit klart att Magnus Bjager blir vår nye utbildningsadministratör. Magnus har arbetat hos oss tidigare. Välkommen tillbaka. Magnus börjar 1/8. Två nya doktorander har antagits

https://www.soch.lu.se/internt/sites/soch.lu.se.internt/files/soch-infoblad-2016-06-16.pdf - 2026-05-30

A Comparison between Indoor and Outdoor Rape Suspects in Sweden

As the number of rapes is increasing in Sweden, and the number of individuals convicted of these crimes is decreasing, it is of importance to study offender characteristics of those committing these crimes and the circumstances in which these crimes are conducted, such as indoors or outdoors. Data from Swedish population-based registers were used to identify individuals suspected of rape, aggravat

Bicontinuous cubic liquid crystalline phase nanoparticles stabilized by softwood hemicellulose

The colloidal stability of lipid based cubosomes, aqueous dispersion of inverse bicontinuous cubic phase, can be significantly increased by a stabilizer. The most commonly used stabilizers are non-ionic tri-block copolymers, poloxamers, which adsorb at the lipid-water interface and hence sterically stabilize the dispersion. One of the challenges with these synthetic polymers is the effect on the i

Sara hallin

“Meet the nitrous oxide reducing microbes in soils and sediments” Mitigating N2O emissions - an ES delivered by soil microbes Sara Hallin Dept. Forest Mycology & Plant Pathology Swedish University of Agricultural Sciences, Uppsala ClimBEco Annual Meeting Aug 24-25, 2017 Höllviken « the microbial zoo » Biomass in soil: 10 ton/ha • Bacteria 1-2 ton Bacteria occupy <0.3% of pore space Fungi: 10 – 100

https://www.cec.lu.se/sites/cec.lu.se/files/sara_hallin.pdf - 2026-05-30