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157 MP200 Driscoll JPP 2023

OP-JPEP230061 1..9 SAI-CH-6: Development of a Short Form of the State Anxiety Inventory for Children At-Risk for Type 1 Diabetes Kimberly A. Driscoll ,1,* PHD, Jessica Melin,2 RN, Kristian F. Lynch,3 PHD, Laura B. Smith,4 PHD, CDCES, and Suzanne Bennett Johnson,5 PHD 1Department of Clinical and Health Psychology, University of Florida, USA 2Department of Clinical Sciences, Lund University, Sweden

https://www.teddy.lu.se/sites/teddy.lu.se/files/2024-01/157_MP200_Driscoll_JPP_2023.pdf - 2026-05-29

LPED 2022 6

Centre for Economic Demography Lund University School of Economics and Management P.O. Box 7083 SE-220 07 Lund, Sweden www.ed.lu/publications/Lund-Papers-in-Economic-Demography/ Childhood neighborhoods and cause-specific adult mortality in Sweden 1939–2015 FINN HEDEFALK, INGRID VAN DIJK, MARTIN DRIBE LUND PAPERS IN ECONOMIC DEMOGRAPHY 2022:6 1 Manuscript for: Childhood neighborhoods and cause-spec

https://www.lusem.lu.se/sites/lusem.lu.se/files/2024-01/LPED%202022%206.pdf - 2026-05-29

F8589a560f8a1c2c43c760851878876c204a1331 Exempel pa antagningsprov till Spra kkonsultprogrammet

Inträdesprov till Språkkonsultutbildningen, Lunds universitet (antagning till ht 2013) INTRÄDESPROV TILL SPRÅKKONSULTUTBILDNINGEN Provet består av tre delar: Ordförståelse, textbearbetning och referat. Det första och det andra delprovet besvaras i detta häfte, men referatet ska skrivas på lösblad. Var noga med att skriva namn och personnummer på varje sida i detta häfte och på varje sida i referat

https://www.lunduniversity.lu.se/sites/www.lunduniversity.lu.se/files/f8589a560f8a1c2c43c760851878876c204a1331_Exempel_pa___antagningsprov_till_Spra__kkonsultprogrammet.pdf - 2026-05-29

LPED 2017 3

Centre for Economic Demography Lund University School of Economics and Management P.O. Box 7083 SE-220 07 Lund, Sweden www.ed.lu/publications/Lund-Papers-in-Economic-Demography/ Becoming American: How Context Shaped Intermarriage during the Great Migration to the United States at the Turn of the Twentieth Century MARTIN DRIBE, J. DAVID HACKER, FRANCESCO SCALONE LUND PAPERS IN ECONOMIC DEMOGRAPHY 2

https://www.lusem.lu.se/sites/lusem.lu.se/files/2024-07/LPED_2017_3.pdf - 2026-05-29

Exploring the Functional Landscape of the p53 Regulatory Domain : The Stabilizing Role of Post-Translational Modifications

This study focuses on the intrinsically disordered regulatory domain of p53 and the impact of post-translational modifications. Through fully atomistic explicit water molecular dynamics simulations, we show the wealth of information and detailed understanding that can be obtained by varying the number of phosphorylated amino acids and implementing a restriction in the conformational entropy of the

Diabetic status and the performances of creatinine- and cystatin C–based eGFR equations

Background. The estimation of glomerular filtration rate (GFR) is one tool to detect renal disease. The most used biomarker remains serum creatinine and the European Kidney Function Consortium (EKFCcrea ) equation is the most validated in Europe. More recently, cystatin C has been proposed as a biomarker. We studied the performances of the EKFC equations in a large cohort of subjects according to

Targeting TUBG1 in RB1-negative tumors

The disruption of microtubule dynamics serves as a pivotal strategy for eliminating tumor cells, despite its accompanying toxicities affecting non-tumor cells. This study investigates the potential of selectively targeting γ-tubulin1 (TUBG1) as a therapeutic strategy in cancer treatment. By elucidating the TUBG1-E2F1-retinoblastoma protein (RB1) network, we introduce a novel compound, 4-(6-((3-Met

Prostate specific antigen concentration at age 60 and death or metastasis from prostate cancer : Case-control study

Objective: To determine the relation between concentrations of prostate specific antigen at age 60 and subsequent diagnosis of clinically relevant prostate cancer in an unscreened population to evaluate whether screening for prostate cancer and chemoprevention could be stratified by risk. Design: Case-control study with 1:3 matching nested within a highly representative population based cohort stu

Predicting Sensitivity to Adverse Lifestyle Risk Factors for Cardiometabolic Morbidity and Mortality

People appear to vary in their susceptibility to lifestyle risk factors for cardiometabolic disease; determining a priori who is most sensitive may help optimize the timing, design, and delivery of preventative interventions. We aimed to ascertain a person's degree of resilience or sensitivity to adverse lifestyle exposures and determine whether these classifications help predict cardiometabolic d

Single-cell multiomics of human fetal hematopoiesis define a developmental-specific population and a fetal signature

Knowledge of human fetal blood development and how it differs from adult blood is highly relevant to our understanding of congenital blood and immune disorders and childhood leukemia, of which the latter can originate in utero. Blood formation occurs in waves that overlap in time and space, adding to heterogeneity, which necessitates single-cell approaches. Here, a combined single-cell immunopheno

HIV-2 mediated effects on target and bystander cells induce plasma proteome remodeling

Despite low or undetectable plasma viral load, people living with HIV-2 (PLWH2) typically progress toward AIDS. The driving forces behind HIV-2 disease progression and the role of viremia are still not known, but low-level replication in tissues is believed to play a role. To investigate the impact of viremic and aviremic HIV-2 infection on target and bystander cell pathology, we used data-indepen

Dip-and-pull ambient pressure photoelectron spectroscopy as a spectroelectrochemistry tool for probing molecular redox processes

Ambient pressure x-ray photoelectron spectroscopy (APXPS) can provide a compelling platform for studying an analyte's oxidation and reduction reactions in solutions. This paper presents proof-of-principle operando measurements of a model organometallic complex, iron hexacyanide, in an aqueous solution using the dip-and-pull technique. The data demonstrates that the electrochemically active liquid

A protein deep sequencing evaluation of metastatic melanoma tissues.

Malignant melanoma has the highest increase of incidence of malignancies in the western world. In early stages, front line therapy is surgical excision of the primary tumor. Metastatic disease has very limited possibilities for cure. Recently, several protein kinase inhibitors and immune modifiers have shown promising clinical results but drug resistance in metastasized melanoma remains a major pr

Different fractions of human serum glycoproteins bind galectin-1 or galectin-8, and their ratio may provide a refined biomarker for pathophysiological conditions in cancer and inflammatory disease.

BACKGROUND: Changes in glycosylation of serum proteins are common, and various glycoforms are being explored as biomarkers in cancer and inflammation. We recently showed that glycoforms detected by endogenous galectins not only provide potential biomarkers, but also have different functions when they encounter galectins in tissue cells. Now we have explored the use of a combination of two galectin

Analysis of Alpha-Synuclein in Malignant Melanoma - Development of a SRM Quantification Assay.

Globally, malignant melanoma shows a steady increase in the incidence among cancer diseases. Malignant melanoma represents a cancer type where currently no biomarker or diagnostics is available to identify disease stage, progression of disease or personalized medicine treatment. The aim of this study was to assess the tissue expression of alpha-synuclein, a protein implicated in several disease pr

TCF7L2 type 2 diabetes risk variant, lifestyle factors, and incidence of prostate cancer.

Variation in transcription factor 7-like 2 (TCF7L2), the strongest genetic risk factor for type 2 diabetes (T2D), may play a role in prostate cancer (PCa) depending on lifestyle factors. The aims of this study were to determine if TCF7L2 rs7903146 is associated with risk of PCa and if the association is modified by lifestyle factors independently of T2D status.

HIF-1α can act as a tumor suppressor gene in murine Acute Myeloid Leukemia.

Self-renewal of hematopoietic stem cells (HSCs) and leukemia-initiating cells (LICs) has been proposed to be influenced by low oxygen tension (hypoxia). This signaling, related to the cellular localization inside the bone marrow niche and/or influenced by extrinsic factors, promotes the stabilization of hypoxia inducible factors (HIFs). Whether HIF-1α can be used as a therapeutic target in the tre

Impact of gene dosage, loss of wild-type allele, and FLT3 ligand on Flt3-ITD-induced myeloproliferation

Acquisition of homozygous activating growth factor receptor mutations might accelerate cancer progression through a simple gene-dosage effect. Internal tandem duplications (ITDs) of FLT3 occur in approximately 25% cases of acute myeloid leukemia and induce ligand-independent constitutive signaling. Homozygous FLT3-ITDs confer an adverse prognosis and are frequently detected at relapse. Using a mou

Molecular microheterogeneity of prostate specific antigen in seminal fluid by mass spectrometry.

OBJECTIVES: Prostate specific antigen (PSA) is a widely used and clinically valuable marker for prostate disease. In order to enable the development of new PSA assays and progress the understanding of the biology of PSA we have analyzed PSA in seminal plasma. Design and methods PSA in seminal plasma from men attending a fertility clinic and healthy controls was analyzed using SDS-PAGE, Western blo