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Aims: The aim of this study was to evaluate the prevalence of triple antithrombotic therapy (TT) (warfarin, aspirin and clopidogrel) in patients following an acute coronary syndrome (ACS), the bleeding risk compared to double antiplatelet therapy (DAPT) (aspirin and clopidogrel) and evaluate the accuracy of the HAS-BLED risk score in predicting serious bleeding events in TT patients. Methods and r

Highly malignant tumors, such as glioblastomas, are characterized by hypoxia, endothelial cell (EC) hyperplasia, and hypercoagulation. However, how these phenomena of the tumor microenvironment may be linked at the molecular level during tumor development remains ill-defined. Here, we provide evidence that hypoxia up-regulates protease-activated receptor 2 (PAR-2), i.e., a G-protein-coupled recept

Androgen receptor (AR) is expressed in all stages of prostate cancer progression, including in castration-resistant tumors. Eliminating AR function continues to represent a focus of therapeutic investigation, but AR regulatory mechanisms remain poorly understood. To systematically characterize mechanisms involving microRNAs (miRNAs), we conducted a gain-of function screen of 1129 miRNA molecules i

Background:Although many low-penetrant genetic risk factors for breast cancer have been discovered, knowledge about the effect of multiple risk alleles is limited, especially in women <50 years. We therefore investigated the association between multiple risk alleles and breast cancer risk as well as individual effects according to age-approximated pre- and post-menopausal status.Methods:Ten previo

Recent public opinion research and elite deliberation has established a particular interest in galvanizing an EU army to better enforce a sense of integration, stability and strengthin the Union. This article proposes an alternative mechanism, privileging Richard Rosecrance’s concept of the ‘virtual state’ as anequally important and worthyfactor contributing to all those aspects. The fourdefining

Preeclampsia (PE) is a serious pregnancy complication that manifests as hypertension and proteinuria after the 20(th) gestation week. Previously, fetal hemoglobin (HbF) has been identified as a plausible causative factor. Cell-free Hb and its degradation products are known to cause oxidative stress and tissue damage, typical of the PE placenta. A1M (α1-microglobulin) is an endogenous scavenger of

Background: Prostate-specific antigen (PSA) has modest specificity for prostate cancer. A panel of four kallikrein markers (total PSA, free PSA, intact PSA, and kallikrein-related peptidase 2) is a highly accurate predictor of biopsy outcome. The clinical significance of biopsy-detectable cancers in men classified as low-risk by this panel remains unclear. Methods: The Malmo Diet and Cancer study

The functions of retinoic acid (RA), a potent morphogen with crucial roles in embryogenesis including developmental hematopoiesis, have not been thoroughly investigated in the human setting. Using an in vitro model of human hematopoietic development, we evaluated the effects of RA signaling on the development of blood and on generated hematopoietic progenitors. Decreased RA signaling increases the

Background. Sunlight exposure and fair skin are major determinants of human vitamin D production, but they are also risk factors for cutaneous malignant melanoma (MM). There is epidemiological evidence that all-cause mortality is related to low vitamin D levels. Methods. We assessed the avoidance of sun exposure as a risk factor for all-cause mortality for 29 518 Swedish women in a prospective 20-

Breast cancer exhibits significant molecular, pathological, and clinical heterogeneity. Current clinicopathological evaluation is imperfect for predicting outcome, which results in overtreatment for many patients, and for others, leads to death from recurrent disease. Therefore, additional criteria are needed to better personalize care and maximize treatment effectiveness and survival.

Genome-wide association studies (GWAS) have transformed our understanding of susceptibility to multiple myeloma (MM), but much of the heritability remains unexplained. We report a new GWAS, a meta-analysis with previous GWAS and a replication series, totalling 9974 MM cases and 247,556 controls of European ancestry. Collectively, these data provide evidence for six new MM risk loci, bringing the t

The coronavirus disease 2019 (COVID-19) pandemic has had a significant impact on the world of sports due to periods of home quarantine, bans against public gatherings, travel restrictions, and a large number of postponed or canceled major sporting events. The literature hitherto is sparse, but early indications display signs of psychological impact on elite athletes due to the pandemic. However, b

Well-characterized archival formalin-fixed paraffin-embedded (FFPE) tissues are of much value for prospective biomarker discovery studies, and protocols that offer high throughput and good reproducibility are essential in proteomics. Therefore, we implemented efficient paraffin removal and protein extraction from FFPE tissues followed by an optimized two-enzyme digestion using suspension trapping

Single-cell RNAseq is a routinely used method to explore heterogeneity within cell populations. Data from these experiments are often visualized using dimension reduction methods such as UMAP and tSNE, where each cell is projected in two or three dimensional space. Three-dimensional projections can be more informative for larger and complex datasets because they are less prone to merging and flatt

Rapport från dokumentstudien Evelina Kallträsk Avdelningen för Riskhantering och Samhällssäkerhet LTH, Lunds universitet 29 november 2019 Isf-Projektet: Dokumentanalys Kartläggning av samverkan och samberoenden för sektorerna elektronisk kommunikation, energiförsörjning och transporter Sammanfattning Följande rapport består av en studie som genomförts inom ramen för ett ISF-finansierat projekt ko

https://www.cencip.lu.se/sites/cencip.lu.se/files/kalltrask_e_2019_kartlaggning_av_samverkan_och_samberoenden_for_sektorerna_elektronisk_kommunikation_energiforsorjning_och_transporter.pdf - 2026-05-29

Brevmall Konstnär l iga fakulteten i Malmö Faststäl ld i Konstnärl iga fakultetsnämnden 2014-09-25 Föreskrifter om handledning och andra resurser för forskarutbildning 1. Handledning och andra resurser Regelverket • HF: 7 kap 34§ ”Till utbildning på forskarnivå får endast så många doktorander antas som kan erbjudas handledning och godtagbara studievillkor i övrigt och som har studiefinansiering en

https://www.konstnarliga.lu.se/sites/konstnarliga.lu.se/files/handledning_och_andra_resurser_2.pdf - 2026-05-29

EU:s dataskyddsförordning och utbildningsområdet KorreKtur Stockholm 2017 SOU 2017:49 Betänkande av Utbildningsdatautredningen EU:s dataskyddsförordning och utbildningsområdet KorreKtur SOU och Ds kan köpas från Wolters Kluwers kundservice. Beställningsadress: Wolters Kluwers kundservice, 106 47 Stockholm Ordertelefon: 08-598 191 90 E-post: kundservice@wolterskluwer.se Webbplats: wolterskluwer.se/

https://www.medarbetarwebben.lu.se/sites/medarbetarwebben.lu.se/files/sou-dsf-utbildningsomradet-juni2017.pdf - 2026-05-29

Thesis_2007_Giovanni_Bettini Aqua-Feminism Water Privatization and Sustainable Development: Insights from a Gender Perspective A case study on Buenos Aires Picture: http://sweb.ws May 23, 2007 Submitted by Supervisor Giovanni Bettini Turaj S. Faran C/O LUMES Dep. of Economic History, LU P.O. BOX 170 P.O. BOX 7083 SE-221 00 LUND SE-220 07 LUND cavetto@hotmail.com turaj.faran@ekh.lu.se LUMES Lund Un

https://www.lumes.lu.se/sites/lumes.lu.se/files/giovanni_bettini.pdf - 2026-05-29

The modified diet history methodology of the Malmö Diet and Cancer cohort 2016-09-05 1 The modified diet history methodology of the Malmö Diet Cancer cohort Edited by Elisabet Wirfält, Emily Sonestedt Resource persons: - Dietary data collection at baseline: Ulrika Ericson (ulrika.ericson@med.lu.se) Peter Wallström (especially supplements) (peter.wallstrom@med.lu.se) - Consultation on dietary data

https://www.malmo-kohorter.lu.se/sites/malmo-kohorter.lu.se/files/mdc_diet_history.pdf - 2026-05-29

Workplace social media monitoring has become increasingly prevalent, raising critical concerns about privacy and fairness in employee-employer relationships. This thesis investigated the associations between the Big Five personality traits and employee perceptions of social media monitoring in the workplace. Using a quantitative research design, the study examined how openness, conscientiousness,