Sökresultat

The proto-oncogene SKI is highly expressed in human myeloid leukemia and also in murine hematopoietic stem cells. However, its operative relevance in these cells remains elusive. We have over-expressed SKI to define its intrinsic role in hematopoiesis and myeloid neoplasms, which resulted in a robust competitive advantage upon transplantation, a complete dominance of the stem and progenitor compar

In families screened for mutations in the BRCA1 or BRCA2 genes and found to have a segregating mutation the breast cancer risk for women shown not to carry the family-specific mutation might be at above "average" risk. We assessed the risk of breast cancer in a clinic based cohort of 725 female proven noncarriers in 239 BRCA1 and BRCA2 families compared with birth-matched controls from the Danish

Mutations in the BRCA1 and BRCA2 genes significantly contribute to hereditary breast cancer and ovarian cancer, but the phenotypic effect from different mutations is insufficiently recognized. We used a western Danish clinic-based cohort of 299 BRCA families to study the female cancer risk in mutation carriers and their untested first-degree relatives. Founder mutations were characterized and the

Identification of Lynch syndrome tumors is challenging. This relates particularly to MSH6-associated cases, which show reduced penetrance of colorectal cancer and a higher age at diagnosis. We recorded the clinical and morphologic features of 52 MSH6-associated colorectal cancers in comparison with MLH1/MSH2-mutant tumors and sporadic mismatch repair-deficient cancers. In the MSH6 subset, we confi

In the present study, we evaluated the cholesterol-lowering effects of different oat bran (OB) preparations, differing regarding their peak molecular weight (MWp) of beta-glucans (2348, 1311, 241, 56, 21 or < 10 kDa), in C57BL/6NCrl mice. The diets were designed to be atherogenic (0.8 % cholesterol and 0.1 % cholic acid), and they reflected the Western diet pattern (41 % energy fat). All OB prepar

Studies have shown that specific characteristics of prevalent vertebral fractures are associated with a markedly low bone mineral density. This study evaluates if these characteristics also predict subsequent fractures.

Förstå, förklara, förbättra TEMATISKA SAMVERKANSINITIATIV | LUNDS UNIVERSITET REDAKTION Redaktör och grafisk form: Bodil Malmström Avdelningen för Samverkan, Lunds universitet. TEXT Catrin Jakobsson, Noomi Egan, Jessika Sellergren, Bodil Malmström och Pia Romare. FOTO Johan Bävman, Salar Haghighatafshar, Catrin Jakobsson, Bodil Malmström, Gunnar Menander, Kennet Ruona, ORBIT Science Village Scandi

https://www.lu.se/sites/www.lu.se/files/forsta_forklara_forbattra_jan_2020_2.pdf - 2026-05-28

Microsoft Word - AMOAH_ANTWI-BOASIAKO_thesis.DOC_Revised_1.DOC 1 LUMES 2002/2003 International Master’s Programme in Environmental Science- LUMES Proliferation of Surface Mining in Ghana: A Threat or a Blessing to the Poor in the Mining areas? A Case Study of Tarkwa Mining Area By Antwi- Boasiako Amoah (Ghana) Email: antwi-boasiako.amoah.355@student.lu.se otaazyak@yahoo.com Supervisor Dr. Alia Ahm

https://www.lumes.lu.se/sites/lumes.lu.se/files/amoah_antwi-boasiako.pdf - 2026-05-28

Thesis_2007_Giovanni_Bettini Aqua-Feminism Water Privatization and Sustainable Development: Insights from a Gender Perspective A case study on Buenos Aires Picture: http://sweb.ws May 23, 2007 Submitted by Supervisor Giovanni Bettini Turaj S. Faran C/O LUMES Dep. of Economic History, LU P.O. BOX 170 P.O. BOX 7083 SE-221 00 LUND SE-220 07 LUND cavetto@hotmail.com turaj.faran@ekh.lu.se LUMES Lund Un

https://www.lumes.lu.se/sites/lumes.lu.se/files/giovanni_bettini.pdf - 2026-05-28

The risk of cancer in men from BRCA1 and BRCA2 families is relevant to define to motivate genetic testing and optimize recommendations for surveillance.

Abstract Objectives: The study aimed to test the construct validity, factor structure and reliability of the 11-item version of the Tampa Scale for Kinesiophobia (TSK-11, Swedish version) among older people (65+) with chronic pain. Design: Methodological study. Subjects: 433 participants with chronic pain (mean age 74.8, 65-98 years) completed postal questionnaires. 264 of the participants complet

Purpose: Lynch syndrome is caused by a germline mutation in a mismatch repair gene, most commonly the MLH1 gene. However, one third of the identified alterations are missense variants with unclear clinical significance. The functionality of these variants can be tested in the laboratory, but the results cannot be used for clinical diagnosis. We therefore aimed to establish a laboratory test that c

Instruktioner till HKBV Leveransmall ver 1.8 2024-04-19 1 Instruktioner för användning av HKBV-leveransmallen + saker att tänka på Vilka data används mallen till?  Leveransmallen används för att leverera både HKBV-data och data från Riksrutorna (Nationella Kustfågelövervakningen) som ligger i HKBV-länen. Ni gör alltså ingen separat leverans av data mha SFTs inmatningsprotokoll för Riksrutor som i

https://www.naturdatavardskap.lu.se/sites/naturdatavardskap.lu.se/files/2024-04/Leveransmall_HKBV_ver1.8_Instruktioner.pdf - 2026-05-28

Instruktioner till HKBV Leveransmall ver 1.9 2025-05-12 1 Instruktioner för användning av HKBV-leveransmallen + saker att tänka på Vilka data används mallen till?  Leveransmallen används för att leverera både HKBV-data och data från Riksrutorna (Nationella Kustfågelövervakningen) som ligger i HKBV-länen. Ni gör alltså ingen separat leverans av data mha SFTs inmatningsprotokoll för Riksrutor som i

https://www.naturdatavardskap.lu.se/sites/naturdatavardskap.lu.se/files/2025-05/Leveransmall_HKBV_2025v1_Instruktioner.pdf - 2026-05-28

Instruktion för att lägga in samverkansprojekt i LUCRIS LUNDS UNIVERSITET Alla anställda med forskande roll på Samhällsvetenskapliga fakulteten ska redan ha lagt in information i LUCRIS om sina forskningsprojekt och publikationer, enligt den miniminivå som finns att hitta på Sam- bibs hemsida. Nu ska du också lägga in dina projekt och aktiviteter som innefattar samverkan med externa aktörer, initi

https://www.psy.lu.se/sites/psy.lu.se/files/lucris_samverkansprojekt.pdf - 2026-05-28

Plasma 25-Hydroxyvitamin D Concentration and Risk of Islet Autoimmunity 1 Plasma 25-hydroxyvitamin D concentration and risk of islet autoimmunity Short running title: 25(OH)D and Islet Autoimmunity Jill M. Norris,PhD1, Hye-Seung Lee,PhD2, Brittni Frederiksen,PhD1, Iris Erlund,PhD3, Ulla Uusitalo,PhD2, Jimin Yang,PhD2, Åke Lernmark,PhD4, Olli Simell,PhD5, Jorma Toppari,PhD5,6, Marian Rewers,PhD7, A

https://www.teddy.lu.se/sites/teddy.lu.se/files/11152017_679_81_mp106a_norris_diabetes_2017_in_press.pdf - 2026-05-28

Recent high-visibility disasters have fueled public and political awareness of the importance of managing and mitigating their consequences effectively. In response, various countries have enacted legislation that demands the evaluation of emergency responses so that lessons for improvement can be learned. A series of field and experimental studies were conducted from 2005 to 2007 to assess the ab

Angiogenesis is one of the hallmarks of breast cancer. The status of angiogenesis is important in therapy choice. Spider telangiectasias (telangiectasias) may reflect an increased ability to form vessels. Our first aim was to identify patient and tumor characteristics associated with the occurrence of telangiectasias at the time of breast cancer diagnosis. The second aim was to study the overall s

The proto-oncogene SKI is highly expressed in human myeloid leukemia and also in murine hematopoietic stem cells. However, its operative relevance in these cells remains elusive. We have over-expressed SKI to define its intrinsic role in hematopoiesis and myeloid neoplasms, which resulted in a robust competitive advantage upon transplantation, a complete dominance of the stem and progenitor compar

Background. Multidisciplinary team (MDT) conferences have been introduced into standard cancer care, though evidence that it benefits the patient is weak. We used the national Swedish Rectal Cancer Register to evaluate predictors for case discussion at a MDT conference and its impact on treatment. Material and methods. Of the 6760 patients diagnosed with rectal cancer in Sweden between 2007 and 20