Filtyp
As the scale of single-cell genomics experiments grows into the millions, the computational requirements to process this data are beyond the reach of many. Herein we present Scarf, a modularly designed Python package that seamlessly interoperates with other single-cell toolkits and allows for memory-efficient single-cell analysis of millions of cells on a laptop or low-cost devices like single-boa
During the early modern period Swedish society was structured by a variety of hierarchies, and the principle of filial deference, or the obedience and recognition children–young or adult–were expected to show their parents, was more or less absolute. These ideas of family hierarchy influenced marriage laws and the formal rules of who was allowed to marry whom. During the 1700s the number of applic
This study introduces silicon substrates with a switchable magnetic contrast layer (MCL) for polarized neutron reflectometry (PNR) experiments at the solid–liquid interface to study soft-matter surface layers. During standard neutron reflectometry (NR) experiments on soft-matter samples, structural and compositional information is obtained by collecting experimental data with different isotopic co
BACKGROUND AND OBJECTIVES: Atrial fibrillation (AF) is associated with inflammation systemically and in the atrial tissue. Oxidized low-density lipoprotein (LDL) is increased in patients with AF and is suggested to be one of the molecules that drives inflammation. Autoantibodies against oxidized LDL and apolipoprotein B100, the protein component of LDL, are linked to atherosclerotic disease. Howev
Injectable bioelectronics could become an alternative or a complement to traditional drug treatments. To this end, a new self-doped p-type conducting PEDOT-S copolymer (A5) was synthesized. This copolymer formed highly water-dispersed nanoparticles and aggregated into a mixed ion-electron conducting hydrogel when injected into a tissue model. First, we synthetically repeated most of the published
PURPOSE: Leukemic stem cells (LSCs) may harbor important resistance to tyrosine kinase inhibitors in chronic myeloid leukemia (CML). We identified Philadelphia chromosome (Ph) positive CD34+CD38- bone marrow cells (here denoted LSCs) and addressed their response-predictive value in CML patients (n=48) subjected to nilotinib in the ENEST1st trial (NCT01061177).EXPERIMENTAL DESIGN: Two flow cytometr
Nanowires (NWs) have unique electrical and optical properties of value for many applications including lighting, sensing, and energy harnessing. Consumer products containing NWs increase the risk of NWs being released in the environment, especially into aquatic ecosystems through sewage systems. Daphnia magna is a common, cosmopolitan freshwater organism sensitive to toxicity tests and represents
Chromosome banding analyses reveal secondary chromosome abnormalities in addition to the MYC translocations t(8;14)(q24;q32), t(8;22)(q24;q11), and t(2;8)(p11;q24) in 60%-80% of Burkitt lymphomas/leukemias (BL). The high incidence of such aberrations indicates that additional changes are important, perhaps necessary, for malignant transformation, i.e., the 8q24/MYC rearrangements may not be suffic
BACKGROUND: Breast cancer detected by screening has an unexplained prognostic advantage beyond stage shift compared with cancers detected clinically. The aim was to investigate biological factors in invasive breast cancer, with reference to mode of detection and rate of death from breast cancer. METHODS: Histology, oestrogen receptor α and β, progesterone receptor, human epidermal growth factor
Interfacial structures on the nanoscale are crucial for a wide field of applications ranging from biological membranes in life sciences through organic solar cells and industrial coatings in soft matter to hard matter structures. The latter include thin film coatings and materials such as magnetic nanoparticles and topological structures like magnetic skyrmions. Advancing such application rests on
A major challenge hampering the industrial and biological exploitation of lipases is the self-limiting effect of the lipolytic reaction. Defying sustained attention throughout history, the influence of lipase catalysed lipolysis on the internal structure of thin triglyceride films has proved elusive. An in-depth understanding of the lipolysis process at the triglycerides/aqueous interface will ass
The structure and function of many proteins are regulated post-translationally through glycan attachment. These glycans, assembled via competing enzymatic reactions, generate diverse glycoform populations - variants sharing a protein backbone but differing in glycan structures. While current analyses often focus on individual glycoforms, we demonstrate that population-level glycoform analysis - in
Slutseminarium Naja Bjørnsson (semitiska språk): Checkpoints in Syrian literature 2014-2019. | Språk- och litteraturcentrum 28 maj Slutseminarium Naja Bjørnsson (semitiska språk): Checkpoints in Syrian literature 2014-2019. 28 maj 2026 09:15 till 11:00 Seminarium Slutseminarium i semitiska språk - arabisk litteraturvetenskap. Seminariet sker på engelska. Diskutant är Anne-Marie McManus (Forum Tran
2012-2014 2007-2010 2006-2007 2005 2011 2010 2016 2015 2014 2013 2012 2011 2010 Malmø Art Academy, Post graduate Diploma MFA Fine Art, Sweden Goldsmiths, University of London, Honours BA Fine Art Practice, United Kingdom Central Saint Martins, University of London, Performance design, United Kingdom Bjørn Ignatius Øchenholts Billedkunstskole, Copenhagen, Denmark Film Editor at DFI / The Danish Fil
https://www.khm.lu.se/sites/khm.lu.se/files/2014cv_helenenymann.pdf - 2026-05-22
1 M al m ö A rt A ca de m y 20 14 –2 01 5 M FA 1 B FA 1 & 2 2 M al m ö A rt A ca de m y 20 14 –2 01 5 Masters of Fine Arts – Year 1 Bachelor of Fine Arts – Year 2 Bachelor of Fine Arts – Year 1 3 Master of Fine Arts Year 1 Alice Angeletti Markus Bråten Dick Joakim Hedlund Hanni Kamaly Youngjae Lih Johan Lundqvist Jan Moszumanski Henrique Pavão Marie Raffn Ana Rebordão Tomas Sjögren Daniel Seferian
https://www.khm.lu.se/sites/khm.lu.se/files/yearbook_2015_mfa1_bfa1-2.pdf - 2026-05-22
We present a detailed comparison of ectopic ossification (EO) found in tendons of biglycan (Bgn), fibromodulin (Fmod) single and double Bgn/Fmod-deficient (DKO) mice with aging. At 3 months, Fmod KO, Bgn KO and DKO displayed torn cruciate ligaments and EO in their quadriceps tendon, menisci and cruciate and patellar ligaments. The phenotype was the least severe in the Fmod KO, intermediate in the
The functions of retinoic acid (RA), a potent morphogen with crucial roles in embryogenesis including developmental hematopoiesis, have not been thoroughly investigated in the human setting. Using an in vitro model of human hematopoietic development, we evaluated the effects of RA signaling on the development of blood and on generated hematopoietic progenitors. Decreased RA signaling increases the
