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BACKGROUND: Viral gene therapy of malignant brain tumors has been restricted by the limited vector distribution within the tumors. Multipotent mesenchymal stromal cells (MSCs) and other precursor cells have shown tropism for gliomas, and these cells are currently being explored as potential vehicles for gene delivery in glioma gene therapy. OBJECTIVE: To investigate MSC migration in detail after i

Tracking techniques are vital for the understanding of the biology and ecology of organisms. While such techniques have provided important information on the movement and migration of large animals, such as mammals and birds, scientific advances in understanding the individual behaviour and interactions of small (mm-scale) organisms have been hampered by constraints, such as the sizes of existing

Det är inte ovanligt att äldre personer söker tilllogopedmottagningama fOr röstbesvär. Det är sannolikt att denna patientgrupp kommer att växa, då antalet äldre blir allt fler. Syftet med denna studie var att undersöka sambandet mellan röstförändringar och ålder hos kvinnor i åldersgruppema 25-35, 50-60 san1t 70-80 år. Urvalet av försökspersoner gjordes från samtliga röstinspelningar av kvi1mliga

För att se om brand regimerna i Sverige före större antropogena påverkningar skett år jämförbara med nutida Kanadensiska brand regimer jämförde jag två datasets av brand storlek och antal bränder. Man kan se likheter när Kanada och Sveriges brand regimer jämfördes, men eftersom sökarean varierade mycket (Kanada: hela landet, Sverige: 608km2) och den temporala upplösningen (Kanada: 41 år, Sverige: To assess if the fire regimes in Sweden before the strong human intervention are comparable to the recent Canadian fire regime I compared two datasets of fire numbers. A likeness could be found when comparing the Swedish and Canadian fire regimes, but due to the differences in study area (Canada: the whole state; Sweden 608km2) and time span (Canada: 41 years, Sweden: 800 years), no significant re

There is a long history of avian studies investigating the impacts of urbanization. While differences in several life-history traits have been documented, either between urban and rural populations or across generalized urbanization gradients, a detailed understanding of which specific environmental variables cause these phenotypic differences is still lacking. Here, we quantified several local en

Det framgår tydligt av lagändringar och motivuttalanden över åren att det har kommit att fästas ett större fokus vid barnets behov av skydd och ett mindre fokus på barnets behov av kontakt. Det följer både av föräldrabalken och barnkonventionen att beslutsfattaren har att göra en konsekvensanalys där långsiktiga och kortsiktiga effekter som kan följa av ett beslut ska beak-tas. Vilken vikt risken Is is clear from the legal amendments and the statements from the prelimina-tory works over the years that there has come to be a greater focus on the child’s need for protection and a lesser focus on the child’s need for contact. It follows from both the Parerantal Code and the Conventions of the rights of the child that the decisionmaker has to make an assessment of long-term and short-terms pot

https://www.sweah.lu.se/sites/sweah.lu.se/files/sweah_folder_sv_2018.pdf - 2026-05-20

Under de senaste åren har den ökande oro för de miljöförödande konsekvenserna av konvent-ionell plast lett till ett ökat intresse för biobaserade och biologiskt nedbrytningsbara plaster. Som förnybara råvaror för dessa plaster har jordbruksbiprodukter framlagts som en lovande källa. Denna studie undersöker olika jordbruksbiprodukter som potentiella råmaterial för biologiskt nedbrytbar plats. DettaIn recent years, concerns about the damaging environmental effects of conventional plastics have surged, by which biobased and biodegradable plastics have been promoted as a favour-able alternative. Agricultural side streams have been proposed as a potential feedstock for extracting components for new compostable polymers. The present study investigates agri-cultural side streams for raw material

This thesis investigates the impact of U.S. sanctions imposed between 2010 and 2012 on Iran’s non-oil exports. Using the Synthetic Control Method (SCM) as the baseline strategy, complemented by an Event Study and a standard Difference-in-Differences (DiD) model, the analysis shows that sanctions led to a sharp and persistent decline in Iran’s export performance relative to a counterfactual scenari

This study presents an example of when the government introduced a regulation that did not coincide research, professional ethics, responsibility or commitments, and led to a conflict between professionals and rulers.In the Swedish statutes regulating opioid maintenance treatment (OMT), a unique definition of the term opiate-dependency, the opiate rule, was introduced in 2010—restricting the targe

Nanoplastics are emerging environmental contaminants that increasingly threaten soil ecosystems, yet their effects on microbial behavior remain poorly understood. This is mainly due to the lack of experimental tools capable of directly observing microbial dynamics in situ under realistic soil-like conditions. Here, we present a proof-of-concept system that enables real-time, high-throughput monito

The spectrum of frontotemporal dementia/amyotrophic lateral sclerosis (FTD/ALS) and Huntington disease (HD) are fatal neurodegenerative disorders with no major disease-modifying therapies. Recent work has shown that the hallmark pathological proteins TAR DNA binding protein of 43 kDa (TDP-43) in FTD/ALS and mutant huntingtin (mHTT) in HD may be interlinked. Furthermore, these disorders share early

Smart microscopy represents a paradigm shift in biological imaging, moving from passive observation tools to active collaborators in scientific inquiry. Enabled by advances in automation, computational power, and artificial intelligence, these systems are now capable of adaptive decision-making and real-time experimental control. Here, we introduce a theoretical framework that reconceptualises sma

The Big Butterfly Count reported its worst results in 14 years of monitoring UK species.

Long-distance migrants face numerous challenges during their migration, with the spring migration timing being particularly important, as early arrival at the breeding grounds often enhances breeding success. Both innate and environmental factors influence migration timing in birds, and the earlier arrival of males than females is common among songbirds breeding in temperate zones. The great reed

Aim: This randomised controlled trial evaluated changes in parental self-efficacy and children's weight, after a Child-Centred Health Dialogue about preventing obesity. Methods: We randomly assigned 37 Child Health Centres in Skåne county Sweden to provide usual care or the dialogue intervention. They included centres from high and low socioeconomic areas. The outcomes were changes in parental sel

Mall för kursplaner på grundnivå och avancerad nivå inom naturvetenskapliga fakulteten MVEC12 Kursplan för Riskanalys inom natur, miljö och hälsa, 15 högskolepoäng, Risk Analysis in Environment and Public Health 15 credits 1. Grundläggande uppgifter Fastställd av naturvetenskapliga fakultetens utbildningsnämnd xxx . Planen träder i kraft 2007-07-01. Kursen är på grundläggande nivå 2. Allmänna uppg

https://www.cec.lu.se/sv/sites/cec.lu.se.sv/files/mvec12_kursplan.doc - 2026-05-20

Alzheimer’s disease (AD) accounts for about 70% of neurodegenerative diseases and is a cause of cognitive decline and death for one-third of seniors. AD is currently underdiagnosed, and it cannot be effectively prevented. Aggregation of amyloid-β (Aβ) proteins has been linked to the development of AD, and it has been established that, under pathological conditions, Aβ proteins undergo structural c

BACKGROUND: This paper investigates the impact of a non-mandatory and age-specific social distancing recommendation on isolation behaviors and disease outcomes in Sweden during the first wave of the COVID-19 pandemic (March to July, 2020). The policy stated that people aged 70 years or older should avoid crowded places and contact with people outside the household.METHODS: We used a regression dis