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Aims: To examine whether the socio-economic determinants of alcohol use found in high-income university student settings are also true of Uganda. Design: Two cross-sectional surveys, conducted in 2005 and 2010, combined into a single dataset. Setting: Mbarara University of Science and Technology (MUST) in southwestern Uganda. Participants: 2,934 students (N in 2005 = 980; N in 2010 = 1,954). To
Echocardiography has a vital role for diagnosing and monitoring infectious endocarditis. The recently published Swedish guidelines for diagnosis and treatment of infectious endocarditis recommend overuse of transoesophageal echocardiography, which is not supported by the literature. The European Society of Cardiology presents a considerably more appropriate opinion.
Conclusion Sentinel lymph node biopsies (SLNBs) can be performed safely and with reasonable accuracy in HNM patients. The outcome provides important prognostic information concerning DFS and further treatment. However, one must recognize that SLNB is a multidisciplinary procedure with a learning curve for all. Objectives To evaluate efficacy of performing SLNBs in a series of consecutive patients
Rational, autonomous agents that are able to achieve their goals in dynamic, partially observable environments are the ultimate dream of Artificial Intelligence research since its beginning. The goal of this PhD thesis is to propose, develop and evaluate a framework well suited for creating intelligent agents that would be able to learn from experience, thus becoming more efficient at solving thei
A capillary filling microfluidic proteomic sample processing system has been realized in an automated set-up. Chip-integrated solid-phase extraction is performed in a 96-array format followed by sequential capillary action elution into a piezoelectric microdispenser and subsequent transfer to MALDI targets. Samples are eluted and deposited in volumes of 200–300 nl. The robotic system offers calibr
Antibodies to citrulline-modified proteins have a high diagnostic value in rheumatoid arthritis (RA). However, their biological role in disease development is still unclear. To obtain insight into this question, a panel of mouse monoclonal antibodies was generated against a major triple helical collagen type II (CII) epitope (position 359-369; ARGLTGRPGDA) with or without arginines modified by cit
Study commissioned by BIL Sweden for the Committee for Producer Responsibility Review (M 2000:01) på uppdrag av BIL Sweden
Many problems concerning resource management in modern communication systems can be simplified to queueing models under Markovian assumptions. The computation of the optimal policy is however often hindered by the curse of dimensionality especially for models that support multiple traffic or job classes. The research focus naturally turns to computationally efficient bounds and high performance he
Thread-Level Speculation can be used to take advantage of multicore architectures for web applications. We have implemented Thread-Level Speculation in the state-of-the-art JavaScript engine V8 instead of using an interpreted JavaScript engine. We evaluate the implementation with the Chromium web browser on 15 popular web applications for 2, 4, and 8 cores. The results show that it is beneficial t
Newton-Raphson and Goldschmidt algorithms can be sped up by using variable latency hardware architectures for rounding division, square root and their reciprocals. A new approach based on a rounding method with remainder estimate calculated concurrently with the algorithm was proposed in [5]. This paper presents an study of the hardware implementation of this approach and shows that does not suppo
In most manufacturing companies, it is necessary to carry inventory to a greater or lesser extent in order to disconnect the activities in the supply chain that are not conducted at the same pace. This way, a smoother flow through the chain, from raw material extraction to arrival at the final customer of a finished product, is facilitated. However, different parts of a company often have conflict
The interactions between airway epithelial cells (AECs) and dendritic cells (DCs) play an important role in the sensitization towards airborne allergens. Not much is known about the underlying mechanisms and novel in vitro approaches are needed, which include the different involved cell types in order to investigate what happens at the molecular level during sensitization. In this project, one aim
In pursuit of a sustainable society, the bike possesses a central importance. It is important that the bike lanes meet the needs in terms of accessibility and safety. In the Netherlands, the UK and Denmark already exists so-called super cycle routes, which have proven to be very successful, as they contributed to the increased cycling, and at same time improved accessibility and comfort for the cy
In the pursuit of a system capable of measuring pain signals in humans we propose a method to differentiate those signals related to pain from those which are not. We performed a time-frequency analysis using the Gabor transform to have complete information about the spectrum and its behaviour through the time to study the main differences over the evoked potentials provoked by both nociceptive an
When viewing moving objects in videos the movement of the eyes is called smooth pursuit. For evaluating the relationship of eye tracking data to the moving objects, the objects in the videos need to be detected and tracked. In the first part of this thesis, a method for detecting and tracking of moving objects in videos is developed. The method mainly consists of a modified version of the Gaussian
A common approach to treat respiratory diseases is with adhesive powder mixtures. These are dispersed into an aerosol upon inhalation. It has been found that the performance of such mixtures can be improved by adding fine particle lactose, but exactly why is yet to be established. Several theories have been proposed by previous studies, but the fundamental mechanism is still unknown. This study w
The HIE-ISOLDE post accelerator at CERN has recently come online, en- abling the use of radioactive ion beams with energies of up to 10 MeV/u. An active target gaseous detector is under development for use in some of the experiments. The first investigation of the electron amplification stage with gas electron multipliers has been performed. To this end, a small prototype GEM detector was built an
For variable-frequency drives, the most common way to apply the desired power to an electrical motor is using PWM modulated signals. Due to high-frequency components, those signals give rise to reflections in the motor cables, radiated noise around the cables and acoustic noise in the motor. In order to avoid those problems, NFO Drives AB develops and produces an alternative to PWM modulation call
The aim of this master's thesis is to establish material models for three rubber materials using macroscopic data collected using Digital Image Correlation, DIC. DIC is a non-contact optical technique for measuring strain and displacement in a material by tracking points on a material during the deformation process.\\ The rubber materials are tested in both uniaxial tension and compression, fr
