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Continuous dopaminergic stimulation (CDS) has become one of the main concepts in present Parkinson's disease (PD) research. This is based on the assumption that CDS, or rather near CDS, is the normal striatal setting in a healthy individual. In PD, the degeneration of dopaminergic neurons leads to a reduced capacity to buffer dopamine, which could increase the vulnerability to a pulsatile administ

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Earth system models (ESMs) are key tools for providing climate projections under different scenarios of human-induced forcing. ESMs include a large number of additional processes and feedbacks such as biogeochemical cycles that traditional physical climate models do not consider. Yet, some processes such as cloud dynamics and ecosystem functional response still have fairly high uncertainties. In t

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The emerging concept of sustainable welfare attempts to integrate environmental sustainability and social welfare research. Oriented at a mid-term re-embedding of Western production and consumption norms into planetary limits, it suggests the development of “eco-social” policies in the rich countries. In this theoretical context, this article empirically investigates the relationships between atti

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Accurate and efficient measurement techniques are needed for exposure assessment of 5G portable devices---which are expected to utilize frequencies beyond 6 GHz---with respect to the radio frequency electromagnetic field exposure limits. Above 6 GHz, these limits are expressed in terms of the incident power density, thus requiring that the electromagnetic fields need to be evaluated with high prec

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This thesis deals with epitaxial growth and optical properties of semiconductor nanowires with implications and insights about materials for solar cells. The chapters leading up to the papers give a broader background and an introduction to the field and include nanowires and their synthesis, semiconductor properties, solar cell operational principles, light interaction with a nanowire array, and

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Objectives: The aims of this study are (1) to compare dual-energy X-ray absorptiometry (DEXA) and bioimpedance for body composition measurements in nondialysis patients with chronic kidney disease, and (2) to investigate factors associated with any measurement differences. Design and Methods: This is a substudy using some baseline data from a randomized controlled clinical trial. One hundred twent

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Mild haemophilia is defined by factor levels between 0.05 and 0.40 IU/mL and is characterised by traumatic bleeds. Major issues associated with mild haemophilia are that it may not present for many years after birth, and that awareness, even within families, may be low. Methodological problems exist in diagnosis, such as inconsistencies in results obtained from different assays used to measure fac

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Objective: To describe the design and rationale for the genetic analysis of acute and chronic cerebrovascular neuroimaging phenotypes detected on clinical MRI in patients with acute ischemic stroke (AIS) within the scope of the MRI-GENetics Interface Exploration (MRI-GENIE) study. Methods: MRI-GENIE capitalizes on the existing infrastructure of the Stroke Genetics Network (SiGN). In total, 12 inte

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The ambition of this two-part article is to argue for immanent critique as a research strategy in sustainability studies. We do this by picking up and developing two central, cross-cutting themes in sustainability research, namely interdisciplinarity and normativity. It is widely suggested that the problem-driven and solution-focused orientation in sustainability studies necessitates interdiscipli

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Retinal pericytes play an important role in many diseases of the eye. Immunohistochemical staining techniques of retinal vessels and microvascular pericytes are central to ophthalmological research. It is vital to choose an appropriate method of visualizing the microvascular pericytes. We describe retinal microvascular pericyte immunohistochemical staining in cryo-sections, whole-mounts, and hypot

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The power exponent α in the temperature dependence of laminar burning velocity [Formula presented]=[Formula presented]α is usually considered an empirical parameter extracted from measurements performed at different temperatures. In this paper an analytical derivation of α is proposed, calculating the power exponent from the overall activation energy as: αTu 0→Tu