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Hedgehog, but not Odd skipped, induces segmental grooves in the Drosophila epidermis.

The formation of segmental grooves during mid embryogenesis in the Drosophila epidermis depends on the specification of a single row of groove cells posteriorly adjacent to cells that express the Hedgehog signal. However, the mechanism of groove formation and the role of the parasegmental organizer, which consists of adjacent rows of hedgehog- and wingless-expressing cells, are not well understood

Measuring density and compressibility of white blood cells and prostate cancer cells by microchannel acoustophoresis

We present a novel method for the determination of density and compressibility of individual particles and cells undergoing microchannel acoustophoresis in an arbitrary 2D acoustic field. Our method is a critical advancement within acoustophoretic separation of biological cells, as the ability to determine the density and compressibility of individual cells enables the prediction and alteration of

A real time multi-objective cyclists route choice model for a bike-sharing mobile application

The attractiveness of cycling-and in particular of bike-sharing systems-as a sustainable alternative of transportation is constantly growing, given the undeniable benefits associated with it. The aim of this paper is to present a multi-objective model based on a Fuzzy Inference System to be embedded in a mobile application that could assist cyclists in the selection of the smartest route to follow

Patients’ views of long-term results of bariatric surgery for super-obesity : sustained effects, but continuing struggles

Background: Bariatric surgery is a standard treatment for severe obesity, but little is known about patients’ perceptions about the long-term impact of such surgery. Objective: The aim of this study was to explore patients’ experiences of living with a bariatric procedure for more than a decade. Setting: University hospital. Methods: At the 10-year follow-up after undergoing Roux-en-Y gastric bypa

Aquaporins : Chemical inhibition by small molecules

The human genome encodes 13 aquaporin isoforms with characteristic substrate specificity that are expressed at specific locations throughout the body. Of these isoforms, AQPs 1-4 serve important functions in renal water reabsorption. Consequently, specific AQP inhibitors have been proposed as 'aquaretics', a new class of drugs suitable to induce diuresis without concomitant salt wasting. Furthermo

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This article seeks to elucidate that influence by examining the Malazim [Lectures] of Hussein al-Houthi, the founder of the Houthi movement in Yemen, and comparing them to the ideas and visions of Hassan al-Banna, the founder and theoretician of the Muslim Brotherhood group, as was evident in the book called: Rasa'il Hassan al-Banna, [Messages of Hassan al-Banna] and it will work to clarify the es

Submerged Landscapes in the Hanö Bay : Early Holocene shoreline displacement and human environments in the southern Baltic Basin

Under istider, när stora mängder havsvatten var bundet i inlandsisar, var den globala havsnivån lägre än idag och stora delar av kontinentalsockeln torrlagd. Den senaste istiden (cirka 115 000–12 000 år sedan) var inget undantag, då torrlagda områden utvecklades till ekologiskt rika kustområden som möjliggjorde människans spridning över världen. När inlandsisarna smältesteg havsnivån och dessa lanDuring times of lower global sea level, vast areas of the coastal shelf were exposed and converted into ecologically diverse coastal landscapes that wereattractive for human occupation. The landscapes were subsequently flooded during the deglaciation, but well-preserved remains of these landscapes andtheir inhabitants can today be found on the seafloor. In the southern Baltic Basin, where the comp

Formalizing Street Vendors: Regulating to improve well-being or to gain control?

Formalization, understood as gaining legal status to develop their businesses, is the mainstream policy to regulate the work of street vendors in most cities in the world. However, formalization policies are criticized by different scholars, and many vendors go back to the streets after formalization despite government efforts. To contribute to this long-standing debate, this chapter explores the

Disinformation

Disinformation re-emerged in the 21st century as a public concern and professional challenge for actors seeking to navigate the new political and information landscape. This has led to a growing discussion among researchers on how disinformation relates to PD theory and practice. This chapter argues that disinformation comes with a set of opportunities for PD that open new perspectives to unresolv

Lesson study as a vehicle for improving SEND teachers’ teaching skills

Purpose: Collaborative professional development for inclusive teaching is a limited area of research, although there is an extensive need for special educational needs and disabilities (SEND) teachers. Research findings of how teachers’ professional development can contribute to support the development of powerful learning situations for all students are presented in this special issue. The aim is

Taxation in Africa since colonial times

This chapter focuses on taxation in Africa since 1900. Using existing data and insights from the literature, the chapter documents taxes collected by colonial and post-colonial states, exploring what was taxed, the types of taxes, the tax revenue patterns and the socio-political contexts shaping taxation policies. It begins by discussing the fundamental principles of taxation and forms of direct a