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The success of sequence capture in relation to phylogenetic distance from a reference genome : a case study of avian haemosporidian parasites

Genomic sequencing of avian haemosporidian parasites (Haemosporida) has been challenging due to excessive contamination from host DNA. In this study, we developed a cost-effective protocol to obtain parasite sequences from naturally infected birds, based on targeted sequence capture and next generation sequencing. With the genomic data of Haemoproteus tartakovskyi as a reference, we successfully s

Resistivity imaging and image analysis for estimating water and solute transport across the capillary fringe in laboratory experiments

This study contains a series of laboratory experiments designed to describe the lateral movement and spatial variability of an infiltrated dye tracer across the capillary fringe of homogenous sand in an aquarium. A combination of image analysis and geoelectrical monitoring was used to track the flow paths of the dye with different hydraulic gradients and infiltration rates. Photographs were taken

Så håller sig fåglarna svala i värmen

Strupfladder och flämtandning är några av tricken som fåglar tar till för att överleva höga temperaturer. I en allt varmare framtid kanske det inte räcker, skriver fågelforskarna Andreas Nord och Susan J. Cunningham.

The influence of business model on the development of 3D food printing technology for dysphagia patients in elderly care

Dysphagia, or difficulty swallowing, affects 10–30 % of persons above 65 years old. Texture-modified, easy-to-swallow, puree-like food in the form of timbales is usually served to this group of patients. Due to the characteristics of timbale, its appearance only remotely reminds of the original ingredients, leading to reduced appetite, reduced nutrition intake, and even malnutrition. 3D food print

Mellan juridisk fixering och flexibilitet i den europeiska AI-förordningen

Det är mycket rörelse på AI-fronten nu – både rättsligt, tekniskt och politiskt. Stefan Larsson, jurist och docent i teknik och social förändring vid Lunds universitet, placerar in EU-lagstiftarens AI-förordning i en både global och svensk kontext. Han beskriver processen bakom lagstiftningen, de etiska och principiella grunderna, och hur EU-lagstiftaren hanterar AI-innovationernas explosionsartad

Digital advocacy and algorithms : Challenges and opportunities for civil society

This chapter is about digital advocacy and civil society in the era of Artificial Intelligence (AI). Social media has often been discussed as a game-changer when it comes to advocacy. The technical structures of social media are continuously changing and, therefore, so are the conditions for digital advocacy. Extensive research has focused on different digital advocacy strategies. However, there h

Preliminary evidence that blocking the uptake of placenta-derived preeclamptic extracellular vesicles protects the vascular endothelium and prevents vasoconstriction

Preeclampsia (PE) is a pregnancy syndrome characterized by hypertension and organ damage manifesting after 20 gestational weeks. The etiology is of multifactorial origin, where placental stress causes increased levels of placenta-derived extracellular vesicles (STBEVs) in the maternal circulation, shown to cause inflammation, endothelial activation, vasoconstriction, and anti-angiogenic activity.

Enabling and impeding factors for organizational adaptive capacity – a review of the literature

Organizations responsible for maintaining critical societal functions must be able to handle both events that can be foreseen and events that come more or less as surprises. Therefore, proactive risk management strategies that build on capacity to adapt to new and unforeseen circumstances must complement strategies that build on the ability to plan for events that can be anticipated on beforehand.

Formation of the bicoid morphogen gradient: an mRNA gradient dictates the protein gradient

The Bicoid (Bcd) protein gradient is generally believed to be established in pre-blastoderm Drosophila embryos by the diffusion of Bcd protein after translation of maternal mRNA, which serves as a strictly localized source of Bcd at the anterior pole. However, we previously published evidence that the Bcd gradient is preceded by a bcd mRNA gradient. Here, we have revisited and extended this observ

Telomerase activation as a possible mechanism of action for psychopharmacological interventions.

Originally studied in relation to aging and cancer research, telomerase is now also investigated in relation to psychiatric disorders and treatments. Based on emerging clinical and preclinical data, we hypothesise that telomerase activation could represent a novel element mediating the mechanism of action of certain psychopharmacological interventions (e.g. antidepressants, lithium and antipsychot

Protein microchip bioassay with dual fluorescent- and MALDI read-out.

Protein Microchip Array technology makes it possible to examine patterns of protein expressions and modifications. Current technologies such as two-dimensional get electrophoresis (2-DE) in combination with mass spectrometry allows the identification of biologically relevant proteins with high resolving power, but has also considerable limitations. Most spots observed in 2-DE are from high abundan

Alpha-ketoglutarate decreases serum levels of C-terminal cross-linking telopeptide of type I collagen (CTX) in postmenopausal women with osteopenia: Six-month study

Several studies have shown that alpha-ketoglutaric acid (AKG) increases serum levels of proline and has beneficial effects on skeletal development. We studied the effect of alpha-ketoglutaric (AKG) acid calcium salt (6 g AKG and 1,68 Ca/day) or calcium alone (1.68 Ca/day) on serum C-terminal cross-linked telopeptide of type I collagen (CTX) and osteocalcin (OC), as well as lumbar spine bone minera

Dykungens dotter : hos H. C. Andersen och Birgitta Trotzig

Hans Christian Andersen's tale "The Marsh King's Daughter" (1858) is analysed in relation to Birgitta Trotzig's prose tale of the same title, Dykungens dotter (1985), with the emphasis on Andersen's tale which would seem to be a pious Christian morality in which evil is destroyed and the powers of light conquer darkness. At the same time, Andersen's symbols make clear that darkness is a necessary

BRCA1-positive patients are small for gestational age compared with their unaffected relatives

The BRCA1 gene is thought to exert its main function early in life. We, therefore, studied the effects of BRCA1 mutations on birth weight and birth length. This was carried out by comparing 33 women with and without mutations. Birth weight and length were obtained from a self-administered questionnaire. BRCA1 mutations carriers had a significantly lower birth weight (P = 0.0041) compared with non-