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Several immunodeficiency-related genes are known and a numb er of disease causing mutations have been identified. Immunodeficiency related mutation information have been collected into IDbases. We are currently maintaining 15 registries, which are available at http://www.uta.fi/imt/bioinfo/. The databases are available for the following disorders: adenosine deaminase, CD3 epsilon, CD3 gamma, JAK3,
A mu-ISLM (micro Immuno Supported Liquid Membrane) extraction system coupled in a sequential injection analysis (SIA) configuration, capable of simultaneous sample cleanup and enrichment was developed. The capacity of the extraction channels - donor and acceptor, respectively - were reduced from originally 10 to 1.65 mu L. The acceptor channel surface was covered with a gold layer enabling immobil
Popular Abstract in Swedish Syftet med denna undersökning är att diskutera inlärares signaler om hjälp att uttrycka sig på främmande språk, här franska, signaler som här kallas ?sollicitationer?. Undersökningen handlar om vilken roll dessa spelar för den fortsatta utvecklingen av samtalet med den infödde talaren, närmare bestämt för att utlösa s.k. SPA (Séquences Potentiellement Acquisitionnelles)The aim of this study is to discuss how ?soliciting? (non-native speakers? requests of native speakers for help in how to express themselves in a foreign language) may play a part in the triggering of SPAs (Séquences Potentiellement Acquisitionnelles or ?learning?teaching sequences?). The beneficial effect of SPAs for learning is still controversial, since no correlation has yet been shown between
The differences in fuel consumption and exhaust emissions for residential areas with different street network designs were investigated. Five areas with three different designs, including a traditional grid network and designs feeding the traffic in from a surrounding street and from a centrally located street, were considered. Differences in total fuel consumption and amount of exhaust emissions
Designers’ work sometimes originates from a simplified view of human demands and needs, which may result in furniture that does not fulfill the user requirements. If we consider old people as one group with fairly similar needs and demands rather than have realistic images of old people as a heterogeneous group there is a tendency that it will result in misguided efforts to design for wellbeing. T
Popular Abstract in Swedish Luften omkring oss består inte bara av gaser. I den finns det mängder av små partiklar. De partiklar som står i fokus i den här avhandlingen är mindre än 10 μm, vilket endast är en femtedel av ett hårstrås diameter. Dessa partiklar är tillräckligt små för att kunna förflyttas långa sträckor i atmosfären och har dessutom visat sig påverka människors hälsa negativt. Man hAerosol particles are found in the whole troposphere. Research regarding these particles has gained increased attention because of the effect the particles have on both health and climate. In the atmosphere, aerosol particles scatter incoming solar radiation and this has a cooling effect on the Earth’s climate. But there are particles, especially those containing soot, which can absorb sun light a
Normal ageing in men is associated with a physiological decline in testosterone levels, but adverse environmental or psychosocial factors may also impair testosterone secretion and cause secondary biological changes. In a number of observational or experimental studies in both animals and man, it has been possible to study the influences on gonadal function of stressful life situations. To underst
Progress in the power conversion efficiency of solar cells based on metal-halide perovskite semiconductors has been astonishing for the past years. During their development, transient effects have been observed that gave rise to an uncertainty associated with the determination of device performance from current density-voltage (J-V) measurements. This effect becomes visible in a dependence of the
Desludging is considered a key step in urban sanitation improvement. Nevertheless, in most urban unplanned settlements, desludging is performed in an unhygienic manner, risking public health. This study used a combination of qualitative and quantitative methods to analyse the underlying factors for unhygienic desludging in three urban unplanned settlements of Dar es Salaam, Tanzania. Factors for u
Net primary production (NPP) is modeled for a coniferous forest in southern Sweden for 2001. The model is based on the light-use efficiency concept where NPP is calculated as a product of absorbed photosynthetically active radiation (APAR) and a light-use efficiency factor (ε). APAR is estimated from the fraction of APAR (FAPAR) multiplied with the daily total amount of incoming PAR. FAPAR is obta
Syftet med uppsatsen är att utreda den föreslagna kriminaliseringens effekt på Sveriges nuvarande eftergiftsprogram samt undersöka dess effektivitet trots avsaknad av ett kronvittnesförfarande. Vidare avser uppsatsen att undersöka om kriminaliseringens effekter kan påverkas. För att utröna kriminaliseringens effekter har VD: n få en central roll i uppsatsens modell, då det endast är han som berörs
OBJECTIVES: To compare and examine whether, when and how patients with lung cancer in three countries, with different survival rates, talk about cigarette smoking and its relationship with help-seeking. DESIGN: A qualitative cross-country comparison with analysis of narrative interviews. SETTING: Participants in Sweden, Denmark and England were interviewed during 2015-2016. Interviews, using a nar
This chapter contains an outline of the Swedish social security system with a focus on sickness benefits in the social security and unemployment insurance. The Swedish legislator’s ambition has been to create parity between different forms of employment as well as between those who are self-employed and those who operate in different company structures. Legislative amendments in this area have mai
Background:Serious illness conversations are an iterative, interprofessional, team-based process that includes recommendations about medical care. Yet, it is not clear how clinicians in different role groups work together in this process.Objectives:We sought to examine how interprofessional clinicians in the medical intensive care unit (MICU) who were trained in the serious illness care program (S
