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The Utility of Maternal Blood S100B in Women with Suspected or Established Preeclampsia—A Systematic Review

Purpose: Preeclampsia is a serious pregnancy complication without curative treatment. The central nervous system (CNS) is affected in severe cases of preeclampsia. Until now, no biomarker or other predictive method has been established for predicting severe CNS injury, including the development of eclampsia and/or long-term complications. In this systematic review, we aimed to investigate the asso

Time series of Sentinel-1 and Sentinel-2 imagery for parcel-based crop-type classification using Random Forest algorithm and Google Earth Engine

Precise statistics about crop types and productions can support establishing more efficient decisions in the food security framework. The applicability of remote sensing imagery has been confirmed worldwide in crop-related studies. In this chapter, time series Sentinel-1 and Sentinel-2 images were integrated, along with crop inventory, to generate crop-type maps in Imperial County, CA, USA, within

Don’t ask, don’t tell (DADT) : under-recognition of breathlessness in clinical care—a national survey

Introduction The recognition of breathlessness in clinical practice appears suboptimal, despite its prevalence and impact. This study aimed to explore the content of clinical conversations about breathlessness and patients’ level of self-reported openness when discussing their breathlessness. Methods A cross-sectional, online survey of Australian adults (≥18 years) stratified to the 2016 National

Mitigation of groundwater salinity vulnerability through land cultivation scenarios

Groundwater in most parts of the world is an important source of agricultural water supply for food production. Soil salinization, however, threatens groundwater quality and may cause irreparable damage to agricultural land. A key to tackling this threat is to analyze the link between agricultural crop water requirements and groundwater quality. This study aimed to investigate salinity effects on

Evaluating Soil Erosion in Dehradun Using the RUSLE Model : Challenges, Impacts, and Policy Strategies for Effective Soil Conservation

Soil erosion poses a significant environmental challenge in Dehradun due to its complex, steep terrain, heavy rainfall, and rapid urbanization. This study employed a Google Earth Engine-based approach to assess the average soil loss annually using the Revised Universal Soil Loss Equation (RUSLE). The analysis used various factors, including rainfall-runoff erosivity (R), soil erodibility (K), slop

Positive correlation between plasma and cerebrospinal fluid galectin-3 in suicide attempters

Objectives: Both depression and suicidal behaviour have been associated with neuroinflammation. Galectin-3 (Gal-3), a protein involved in microglial activation, has been linked to pro-inflammatory cytokines and the severity of depressive symptoms. The extent to which peripheral levels of Gal-3 reflect neuroinflammation is unknown, as is the relationship between Gal-3 and suicidality. Methods: Bloo

CoxSE : Exploring the potential of self-explaining neural networks with Cox proportional hazards model for survival analysis

The Cox Proportional Hazards (CPH) model has long been the preferred survival model for its explainability. However, to increase its predictive power beyond its linear log-risk, it was extended to utilize deep neural networks, sacrificing its explainability. In this work, we explore the potential of self-explaining neural networks (SENN) for survival analysis. We propose a new locally explainable

Heart rate response and recovery in cycle exercise testing : normal values and association with mortality

Aims. Chronotropic incompetence and impaired heart rate (HR) recovery are related to mortality. Guidelines lack specific reference values for HR recovery. We defined normal values and studied blunted HR response and recovery and mortality risk. Methods and results. We included 9917 subjects (45% females) aged 18–85 years who performed a cycle exercise test. We defined normal values for peak HR, HR

Upper airway microbiome transplantation for patients with chronic rhinosinusitis

Background: Chronic or recurrent rhinosinusitis without polyps (CRSsNP) is characterized by a persistent inflammation of the sinonasal mucosa. The underlying cause is unclear but increasing interest has been directed toward changes in the sinonasal microbiome as a potential driver. Methods: Twenty-two patients diagnosed with CRSsNP were treated with antibiotics for 13 days, followed by 5 consecuti

A prospective observational study on persistent postoperative pediatric pain, 4P : The study protocol

BACKGROUND: Access to adequate pain treatment is a fundamental right, yet international data suggest that a considerable number of children experience acute and persistent pain. Little is known about the occurrence of both acute and persistent pain in children. The incidence of persistent postoperative pain in children is an unexplored area but international studies suggest that many children expe

eHealth in Pediatric Surgery : Impact on Postsurgical Care After Reconstructive Surgery for Anorectal Malformations and Hirschsprung's Disease

Background: To support care after discharge following surgery for anorectal malformations (ARM) and Hirschsprung's disease (HD), an eHealth device was invented, offering families bilateral communication through chat, photo, questionaries and video. Aim: To explore the impact of eHealth on postoperative patterns of expert consultation, complications and treatment after discharge following surgery f

Swedish national cohort of children living with long-term respiratory support (DISCOVERY-P) : cohort profile

Purpose Children living with respiratory support rely on medical technology, either fully or partially, throughout the day to meet their breathing requirements. Although children and young people living with respiratory support at home undergo long-term treatments and make extensive use of health and social care services, there is a notable absence of comprehensive outcome data on this group. The

pre-SUCCECS : Lessons learned from implementing resuscitation and stabilisation with an intact cord during caesarean sections – Focus group discussions with implementation teams

Objective: The primary aim of this study was to explore the lessons learned from implementing a procedure of resuscitation and stabilization with an intact umbilical cord for preterm and term infants requiring resuscitation or stabilization during emergency caesarean sections. Methods: Data were collected by two focus group discussions and one individual interview. Participants were members of imp

Cyclin A1 expression and associations with disease characteristics in childhood acute lymphoblastic leukemia.

A critical cell cycle regulatory protein, cyclin A1, has been implicated in the development of acute myeloid leukemia (AML). Here, we have examined the expression and clinical significance of cyclin A1 in childhood acute lymphoblastic leukemia (ALL). Cyclin A1 was highly expressed in lymphoblastic leukemic cell lines and in 22 of 30 ALL patients (73%). Cyclin A1 expression correlated with patient

Effects of atmospheric dispersion on the PSF background level

Atmospheric dispersion represents a relatively overlooked problem in connection with the ultimate quality of ELT images corrected by adaptive optics (AO). The aim of this paper is to evaluate the contribution from atmospheric dispersion to the background level of the point-spread function (PSF). Since proper suppression of this level is important for the prospects for direct exo-planet observation