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The main goal of this article is to evaluate the relationship between the spatial distribution of the population of the city of Belo Horizonte, one of the largest cities in South America, and its public transport network, seeking to ascertain whether the current bus network is able to meet the needs of the population. The methodology was based on data processing and vector information from differe
In the context of the COVID-19 pandemic, governments worldwide face the challenge of designing tailored measures of epidemic control to provide reliable health protection while allowing societal and economic activity. In this paper, we propose an extension of the epidemiological SEIR model to enable a detailed analysis of commonly discussed tailored measures of epidemic control—among them group-sp
Magnetic Resonance Spectroscopy (MRS) allows for the quantification of neurotransmitters, antioxidants, energy-metabolism, membrane components and cellular viability markers present in the brain. This technology has been used in preclinical studies and later extended to be used in humans, where it offers an attractive non-invasive approach complementary to other anatomical imaging modalities (e.g.
Contemporary institutions engaged in extending micro-loans do not usually grant such loans to the poor due to the latters’ inability to provide appropriate collateral and their insufficient creditworthiness. In modern times the Dutch East-India Company created a financial instrument called the “transportbrief” which enabled poor employees of the Company to obtain loans on the financial market. The
Over the past few years, a growing body of work in economic geography and innovation studies has enhanced our understanding of forms and determinants of regional industrial path development. The importance of policy, however, has received limited attention and accordingly, the role of policy for the emergence and development of new regional industrial growth paths remains largely unexplored. This
Molecular dynamic simulation of nanosized single-crystal copper beams loaded in tension at different strain rates until necking has been performed for two different crystallographic orientations, the [100]- and the [110]-orientations. The molecular dynamics freeware code LAMMPS was employed for the simulations. It was found that, at low enough strain rates, single necking was obtained for both cry
Where and how new industrial paths emerge are much debated questions in economic geography, especially in light of the recent evolutionary turn. This article contributes to the ongoing debate on path creation with a new analytical framework that specifies the formation of generic resources in embryonic industries. It suggests that path creation processes are not only conditioned by preexisting reg
Rodent models of L-DOPA-induced dyskinesia (LID) are essential to investigate pathophysiological mechanisms and treatment options. Ratings of abnormal involuntary movements (AIMs) are used to capture both qualitative and quantitative features of dyskinetic behaviors. Thus far, validated rating scales for the mouse have anchored the definition of severity to the time during which AIMs are present.
A method for screening of triazine herbicides in surface and waste water is presented. The method is based on an enzyme flow immunoassay (EFIA) for the detection of the free fraction of a horse radish peroxidase (HRP)-labelled antigen (tracer). This was accomplished by trapping the bound tracer fraction in a Protein G column, allowing the residual free tracer fraction to pass and be detected spect
The effects of temperature-dependent thermophysical properties on droplet flow characteristics in a parallel-plate channel at submicron scale are investigated. The dissipative particle dynamics method with many-body (MDPD) and energy conservation (DPDe) configurations (MDPDe) was used. Droplet flows were simulated to study the effects of the temperature difference between top and bottom walls, bod
A two-step Design of Experiments (DoE) strategy followed by a two-liquid-phase system (2LPS) was applied to enhance the ɛ-caprolactone yield in the cyclohexanone monooxygenase (CHMO)-alcohol dehydrogenase (ADH) convergent cascade system. The key reaction parameters were identified and optimized for the determination of an optimal operational window for the aqueous media. In the 2LPS system, high p
BACKGROUND: Guidelines recommend estimation of glomerular filtration rate (eGFR) prior to iodine contrast media (CM) examinations. It is also recommended that absolute eGFR in mL/min, not commonly used relative GFR (adjusted to body surface area; mL/min/1.73 m(2)), should be preferred when dosing and evaluating toxicity of renally excreted drugs.PURPOSE: To validate the absolute Lund-Malmö equatio
Environmental loads from the building and its services must be minimised. The study aims to determine material quantities, manufacturing energy and how material choice affect manufacturing energy. An inventory of materials in domestic water, waste water, space heating and ventilation services are made and manufacturing energy are calculated based on LCA’s. Finally energy need for alternative mater
Purpose: The aim of the study was to explore patients’ long-term experience of a congenital hand problem, and the consequences for daily life. Method: Fifteen participants with a median age 24 years (17–55 years), born with thumb hypoplasia/aplasia or thumb duplication were interviewed using a semi-structured interview guide. The interviews were subjected to qualitative content analysis. Results:
This chapter presents key energy use figures and explores the energy saving potential for electric lighting in office buildings based on a review of relevant literature, with special emphasis on a North European context. The review outlines that an energy intensity of around 10 kWh/m2yr is a realistic target for electric lighting in future low energy office buildings, based on theoretical calculat
