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In its proposed 2023 Critical Raw Materials Act, the European Commission considers access to critical raw materials within its territory as key to both the green transition and to reduce import dependencies. This onshoring of extractivist practices warrants a critical analysis that reflects on the justice implications this may have for local communities. Therefore, I apply an integrated post-struc
Border carbon adjustment is an economic instrument being discussed more frequently as a possible solution to address carbon leakage, which is an issue for many developed countries. Developed countries are showing interest in this instrument to protect domestic industries from carbon leakage to countries that do not tax carbon. There is however concerns from developing countries that border carbon
Efterfrågan på sockerrör har de senaste åren ökat i takt med att fler länder strävar efter att minska sitt beroende av fossila bränslen. Som en följd har antalet sockerrörsodlingar kraftigt ökat i Brasilien vilket medfört en oro inför vilka effekter denna omvandling av ursprunglig mark till sockerrörsodling har på lokala hydrologin och klimatet. I det här arbetet har påverkan av sockerrörs expanThe demand for sugarcane has increased in recent years as more countries desire to reduce its dependence of fossil fuels. Therefore, the number of sugarcane plantations has rapidly increased in Brazil which raises concerns for what effect these conversion of original land to sugarcane plantations have on local hydrology and climate. In this thesis, the effects of sugarcane expansion on surface ru
The current patterns of consuming and producing German coffee cause environmental impacts. Identifying the most relevant environmental impacts (hot spots) along the global value chain of German coffee is the first step to improve its environmental performance. Hot spots need immediate attention from companies, practitioners, and scientists in order to create sustainable solutions. The purpose of
In Zambia, the privatisation of state owned companies is challenging job security, working conditions and workers’ rights. It has also weakened the role of government as a regulator of labour legislation, which in Zambia is quite progressive, compared to other countries in the region. Workers struggle to survive and therefore turn to trade unions in order to change their situation. This study exam
Enligt artikel 1 i den Europeiska konventionen för de mänskliga rättigheterna och de grundläggande friheterna (EKMR) måste de fördragsslutande staterna inom ramen för sin jurisdiktion garantera konventionens fri- och rättigheter. Denna skyldighet är främst territoriell, men i exceptionella fall medges vissa undantag. Uppsatsen behandlar dessa undantag såsom de utvecklats i Europadomstolens praxis According to Article 1 of the European Convention on Human Rights and Fundamental Freedoms (ECHR) the contracting parties must secure the conventional rights within their jurisdiction. The obligation is primarily territorial but in exceptional cases it can be extended to apply extraterritorially. This paper will investigate the development of the case law of the European Court of Human Rights (the
Purpose: Although adjuvant polychemotherapy improves outcomes for early breast cancer, the significant variability in terms of pharmacokinetics results in differences in efficacy and both short and long-term toxicities. Retrospective studies support the use of dose tailoring according to the hematologic nadirs. Methods: The SBG 2004-1 trial was a randomized feasibility phase II study which assesse
Background: An important aspect of research regarding the implementation of evidence-based practice is the sustainability and long-term stability of a programme. There is a need to measure these critical components for establishing successful programmes. Aim: The aim was to develop and pilot test the sustainable implementation scale (SIS) for measuring the critical components in the sustainable im
A search for long-lived, massive particles predicted by many theories beyond the Standard Model is presented. The search targets final states with large missing transverse momentum and at least one high-mass displaced vertex with five or more tracks, and uses 32.8 fb-1 of s=13 TeV pp collision data collected by the ATLAS detector at the LHC. The observed yield is consistent with the expected backg
Background: The aim was to determine prevalence and age at seroconversion of thyroid autoimmunity in relation to islet autoantibodies, gender and HLA-DQ genotypes in children with increased risk for type 1 diabetes followed from birth. Methods: In 10-year-old children (n = 1874), blood samples were analysed for autoantibodies against thyroid peroxidase (TPOAb), thyroglobulin (TGAb), glutamic acid
Introduction: Hip fractures are a common problem of the elderly population with significant mortality and morbidity. The choice between total hip arthroplasty (THA) and hemiarthroplasty depends on multiple factors including comorbidity. The Swedish Hip Arthroplasty Register (SHAR) provides a unique opportunity to study mortality and revision rates in this population. Linkage with government databa
Background: Neuropathic pain is an increasingly prevalent condition and has a major impact on health and quality of life. However, the risk factors for the development and maintenance of neuropathic pain are poorly understood. Clinical, genetic and psychosocial factors all contribute to chronic pain, but their interactions have not been studied in large cohorts. The DOLORisk study aims to study th
The primary focus of this review is a discussion regarding in vitro media for colon release, but we also give a brief overview of colon delivery and the colon microbiota as a baseline for this discussion. The large intestine is colonized by a vast number of bacteria, approximately 10
Background: Circulating tumor cells (CTCs) carry independent prognostic information in patients with metastatic breast cancer (MBC) on different lines of therapy. Moreover, CTC clusters are suggested to add prognostic information to CTC enumeration alone but their significance is unknown in patients with newly diagnosed MBC. We aimed to evaluate whether longitudinal enumeration of circulating tumo
Objective: To assess the relative validity of two diet assessment methods, an extensive quantitative food frequency questionnaire (method A) and a novel shorter quantitative food frequency questionnaire with a 14 day food record (method B). Design: A randomized prospective cohort study. Setting: General community. Subjects: 206 residents of the town of Malmö, aged between 50-69 years, 101 men and
Eight different generations of dolerite dykes crosscutting the Paleoproterozoic basement in West Africa and one in South America were dated using the high precision U–Pb TIMS method on baddeleyite. Some of the individual dykes reach over 300Â km in length and they are considered parts of much larger systems of mafic dyke swarms representing the plumbing systems for large igneous provinces (LIPs).
Class Ib ribonucleotide reductases (RNR) utilize a di-nuclear manganese or iron cofactor for reduction of superoxide or molecular oxygen, respectively. This generates a stable tyrosyl radical (Y·) in the R2 subunit (NrdF), which is further used for ribonucleotide reduction in the R1 subunit of RNR. Here, we report high-resolution crystal structures of Bacillus anthracis NrdF in the metal-free form
Objectives This study aimed to investigate the importance of potentially inappropriate medications, number of medications and chronic conditions for the risk of hospitalisation among an elderly population. Design This is a case-control study. Setting Population-based study in 2013 of all individuals aged 75 years and older (17 203) in the county of Blekinge in the southeast of Sweden. Participants
The geomagnetic dipole moment (GDM) modulates the production rates of cosmogenic radionuclides via the shielding of galactic cosmic rays. Therefore, it is possible to use this linkage to reconstruct past changes in the GDM based on cosmogenic radionuclide records from natural archives such as ice cores. Here we present a GDM reconstruction based on 10Be and 36Cl data from two Greenland ice cores f
Alternative reproductive tactics (ARTs) have provided valuable insights into how sexual selection and life history trade-offs can lead to variation within a sex. However, the possibility that tactics may constrain evolution through intralocus tactical conflict (IATC) is rarely considered. In addition, when IATC has been considered, the focus has often been on the genetic correlations between the A
