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Outcomes for patients with oesophago-gastric cancer are variable across Europe. The reasons for this variability are not clear. The aim of this study was to describe and analyse clinical pathways to understand differences in service provision for oesophageal and gastric cancer in the countries participating in the EURECCA Upper GI group.

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IDO1 can be induced by interferon gamma (IFN-γ) in multiple cell types. We have earlier described that the DNA methyltransferase inhibitor zebularine also induces IDO1 in several rat cell clones. We now describe a synergistic induction of IDO1 expression by IFN-γ and zebularine. To elucidate the mechanism of the IDO1 induction we have studied the methylation status in the promoter region of the ID

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OBJECTIVES:: To compare the plasma volume (PV) expanding effect of a fast infusion rate with that of a slow infusion rate of a fixed volume of 5% albumin, of the synthetic colloids, 6% hydroxyethyl starch 130/0.4 and 4% gelatin, and of 0.9% NaCl in a rat sepsis model and to compare the plasma-expanding effect among these fluids. DESIGN:: Prospective, randomized animal study. SETTING:: University h

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Results are presented of a search for any particle(s) decaying to six or more jets in association with missing transverse momentum. The search is performed using 1.34 fb(-1) of root s = 7TeV proton-proton collisions recorded by the ATLAS detector during 2011. Data-driven techniques are used to determine the backgrounds in kinematic regions that require at least six, seven or eight jets, well beyon

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A search is presented for production of dark-matter particles recoiling against a leptonically decaying Z boson in 20.3 fb(-1) of pp collisions at root s = 8 TeV with the ATLAS detector at the Large Hadron Collider. Events with large missing transverse momentum and two oppositely charged electrons or muons consistent with the decay of a Z boson are analyzed. No excess above the Standard Model pred

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Electrical wiring of different types of pyranose oxidase (P20) (fungal wild type, recombinant wild type with a hexahistidine tag, mutant form E542K with a hexa-histidine tag) from Trametes multicolor, and recombinant P20 from Coriolus sp. overexpressed in Escherichia coli as well as of pyranose dehydrogenase (PDH) from Agaricus meleagris and Agaricus xanthoderma with an osmium redox polymer (poly(

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We describe a novel method for determining weak association constants of oligomeric protein complexes formed transiently under equilibrium conditions. This type of equilibrium process is recognized as being biologically important, but generally hard to study. Heteronuclear spin relaxation rates measured at multiple protein concentrations are analyzed using relaxation rates predicted from hydrodyna

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Grass pea (Lathyrus sativus) is a leguminous food crop, grown mainly in the tropical and subtropical regions. It has valuable nutrients, however consumption of the seeds is reported to cause lathyrism, due to the presence of a non-protein amino acid (?-ODAP). The present study deals with the development of a process for reducing the ?-ODAP content in grass pea seeds. The consequences of processin

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Research within contingency theory recognizes and postulates the relevance of contextual factors to the design of organizations. Thus organizations are dependent on the environments in which they operate and on the technologies they utilize. Organizations therefore need to process information about their environments and technologies. Information systems, including computerized information sytems,

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The majority of approaches for mass appraisal are based on global statistical models that take into account property characteristics, and, in developing countries, location variables are not often explicitly considered. The present study uses Geographic Information Systems (GIS) as an analytical tool to develop a number of location variables and to analyze their impact in the value of properties.

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A discussion on whether different national interpretations sit comfortably with the rationale for the uniform Court of Justice term "worker" and whether this situation can be justified in the light of the potential unlevelling of the internal market and Article 30 of the Charter of Fundamental Rights

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The use of polymers for the delivery of drugs has increased dramatically in the last decade. To ensure the desired properties and functionality of such substances, adequate characterization in terms of the molar mass (M) and size is essential. The aim of this study was to evaluate the changes in the M and size of PVP-b-PAMPS when the amounts of the synthesis reactants in the two-step radical react

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AIM: To investigate the effects of a case management intervention for community-dwelling frail older people, with functional dependency and repeated contacts with the healthcare services, focusing on loneliness, depressive symptoms and life satisfaction.DESIGN: A two-armed, nonblinded, randomised control trial with repeated follow-ups, of N = 153 participants at baseline allocated to an interventi

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OBJECTIVES: In this study, a systematic analysis was conducted of phasic intracoronary pressure and flow velocity in patients with severe aortic stenosis (AS) and coronary artery disease, undergoing transcatheter aortic valve replacement (TAVR), to determine how AS affects: 1) phasic coronary flow; 2) hyperemic coronary flow; and 3) the most common clinically used indices of coronary stenosis seve

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Populärvetenskaplig sammanfattning: Under de senaste 300 åren har jordbrukslandskapet i Sverige genomgått stora förändringar. Detta började med att bönderna i slutet av 1600-talet erhöll en stor del av adelns jord. De fick således förvalta sin egen vinst, vilket resulterade i en rad nyodlingar och tekniska hjälpmedel. I början av 1900-talet introducerades konstgödslet och efter andra världskriget Human-induced eutrophication has rapidly become one of the most important environmental issues. The problem is largely due to the shift in agricultural practices. Farming methods have become more efficient during the last 300 years. Watercourses have been straightened out and wetlands have been reduced to increase agricultural landuse. Since the end of the 1940s, fertilization has increased dramat

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Populärvetenskaplig sammanfattning: Kvävebelastningen på sjöar och hav har ökat markant de senaste tiotal åren. Jordbruket står för ca 50 % av de svenska kväveutsläppen som människan bidrar till. En ökad kvävebelastning på haven kan leda till övergödning, vilket får en stor negativ effekt på vattenekosystemen. Ett sätt att minska övergödningsproblematiken är att öka vattnets uppehållstid i landskaPolitical decisions have resulted in more focus on how to optimize wetlands natural ability to lower nitrogen fluxes in order to minimize the problem with eutrophication in costal areas. However there is no exact knowledge how to calculate the effectiveness of nitrogen removal in wetlands with natural water flow due to the many biochemical and hydrological processes that interact. In this study tw