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Current hemophilia B treatment guidelines recommend routine prophylaxis with factor IX (FIX) replacement products, tailored to maintain plasma activity at levels that will prevent bleeds. However, plasma FIX activity may not be the primary determinant or best indicator of hemostatic efficacy due to its extravascular distribution. FIX replacement therapy has evolved to include extended half-life (E
This thesis deals with the development of new reaction methodology for stereoselective synthesis, as well as total synthesis of natural products and investigations of the stereochemical outcome in the Mukaiyama aldol reaction. Chapter 2 describes efforts made towards the total synthesis of the oxindole natural products perophoramidine and the communesin. The first part of this chapter aims to de
The Convention on Biological Diversity (CBD) was designed in accordance with the framework protocol approach, which comprises treaty bodies such as Conferences of the Parties (COP) and compliance mechanisms and sets out broad standards to be made more precise through the making of protocols. The CBD’s third objective, access and equitable sharing of the benefits arising from the utilization of gen
Popular Abstract in English Vernacular (local) architecture is in danger and about to disappear in several parts of the world. What we call native, traditional and handmade will disappear gradually and then the true meaning of vernacular vanishes. The present thesis shows that the disappearance of vernacular traditional skills creates an increasing threat to the existence of desert vernacular archDesert vernacular architecture has always been the product of a sustainable building cycle. People inherited the traditional way of building from their ancestors and the knowledge was transferred and developed from one generation to another. Inhabitants responded to their environment and climate through trial and error in a way that satisfied their needs and aspirations to create a developing buil
The emancipatory appropriation of space, in the sense making personal adjustments and manoeuvres in order to raise a sense of space, can be understood in terms of giving and taking form, or what Catherine Malabou calls “plasticity”. Spatial production is in this sense defined relationally and cannot be fully provided by programmed architectural functions. That kind of relational and emancipatory vThe emancipatory appropriation of space, in the sense making personal adjustments and manoeuvres in order to raise a sense of space, can be understood in terms of giving and taking form, or what Catherine Malabou calls “plasticity”. Spatial production is in this sense defined relationally and cannot be fully provided by programmed architectural functions. That kind of relational and emancipatory v
https://www.ht.lu.se/serie/1700528/ - 2026-07-06
This essay is about the “forest finns” in Sweden. That is a well known conception when you talk about the extensive immigration of a finish population to Norway and Sweden during the 17th and 18th century. They colonized the big, unoccupied forests in the middle and northern parts of Sweden. The topic for this text is religion and folklore among the finish immigrants. In different historic source
The aim of this study was to explore how general practitioners cope with the challenges they face when trying to provide effective interventions to pain patients within the organizational context of a health center. Based on interviews with 15 Swedish providers, the study suggests that the challenges that general practitioners experience in the consultations with patients must be u
Titti MattssonBarnet och rättsprocessen: Rättssäkerhet, integritetsskydd och autonomi i samband med beslut om tvångsvårdDatum för disputation: den 9 november 2002Fakultetsopponent: professor Trude HaugliÄmne: socialrättAbstractVad är barnets bästa i en domstolsprocess? Hur skall barns behov och intressen tillvaratas under utredningsarbete och beslut, och av vem? I vilken utsträckning skall barn få
https://www.jur.lu.se/forskning/disputationer/disputationer-2002 - 2026-07-07
Abstract In childhood atopic dermatitis (AD) is the most frequent inflammatory condition. Validated eczema questionnaires have been available for schoolchildren only, but the incidence of atopic dermatitis is highest during infancy. Evidence is needed on the further development of asthma, and rhinitis in these infants with AD and on remission of AD in children. We aimed to validate a parental ques
