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Invasive Fusobacterium necrophorum infections and Lemièrre's syndrome: the role of thrombophilia and EBV.

The purpose of this investigation was to describe the clinical spectrum of invasive Fusobacterium necrophorum infections and Lemièrre's syndrome, to examine the role of underlying thrombophilia and concomitant mononucleosis in Lemièrre's syndrome, and to describe thromboembolic complications. Patients with invasive F. necrophorum infections were identified either prospectively or retrospectively t

A comparison of the effects of carvedilol and metoprolol on well-being, morbidity, and mortality (the "patient journey") in patients with heart failure - A report from the Carvedilol or Metoprolol European Trial (COMET)

OBJECTIVES This study was designed to investigate the loss of well-being, in terms of lift-years, overall and in patients randomized to metoprolol versus carvedilol in the Carvcdilol Or Metoprolol European Trial (COMET). BACKGROUND The ultimate objectives of treating patients with heart failure are to relieve suffering and prolong life. Although the effect of treatment on mortality is usually desc

Practice and knowledge of cricoid pressure in southern Sweden

BACKGROUND: For 40 years cricoid pressure has been used to prevent regurgitation of gastric contents during induction of anaesthesia. Recent studies have emphasised use of more moderate force so as not to deteriorate ventilation or endotracheal intubation. This study was undertaken to assess the current practice and knowledge of cricoid pressure among anaesthesia personnel in southern Sweden. METH

Longitudinal movements and resulting shear strain of the arterial wall

There has been little interest in the longitudinal movement of the arterial wall. It has been assumed that this movement is negligible compared with the diameter change. Using a new high-resolution noninvasive ultrasonic method, we measured longitudinal movements and diameter change of the common carotid artery of 10 healthy humans. During the cardiac cycle, a distinct bidirectional longitudinal m

The salivary mucin MG1 (MUC5B) carries a repertoire of unique oligosaccharides that is large and diverse

The high-molecular-mass salivary mucin MG1, one of two major mucins produced by human salivary glands, plays an important role in oral health by coating the tooth surface and by acting as a bacterial receptor. Here this mucin was purified from the submandibular/sublingual saliva of a blood group O individual. The presence of MUC5B as the major mucin in this preparation was confirmed by amino acid

Frequent finding of the androgen receptor A645D variant in normal population.

Background: The androgen receptor A645D mutation has been described in one patient with ambiguous genitalia and one boy with normal phenotype. Objective: Because of this phenotypic variation, we screened a cohort of men from the general population (n = 293) as well as men with the following disorders of the genital tract for the mutation: men with prostate cancer (n = 89), testicular cancer (n = 8

Lung function in children born after foetal growth restriction and very preterm birth

Aims: To assess lung function at early school age in children delivered at very early gestation owing to intrauterine growth restriction and abnormal foetal blood flow (IUGR). Methods: Spirometry was performed at median age 8.4 (range 6.5-10.7) years in 31 children born preterm with IUGR (PT-IUGR) with a median (range) birth weight (BW) of 650 (395-976) g and median (range) gestational age 27 (24-

Pulsations in the umbilical vein during labor are associated with increased risk of operative delivery for fetal distress.

OBJECTIVES: Under physiological conditions the blood flow velocity waveform in the umbilical vein (UV) has an even non-pulsating pattern. Pulsations in the UV have been described in human fetuses exposed to chronic hypoxia and heart failure. Current techniques for fetal surveillance during labor and delivery involve a risk of both over- and underestimation of fetal hypoxia. We aimed to examine whe

Automatic fermentation control based on a real-time in situ SIRE (R) biosensor regulated glucose feed

Monitoring and regulation of fermentations is of a paramount industrial and academic importance in order to keep conditions optimal during the entire process. Established techniques employed today include HPLC and spectrophotometry, which both have the disadvantage that broth samples have to be drawn from the fermentor and that they often require sample pre-treatment. The objectives of this study

Anticoagulation control in Sweden: reports of time in therapeutic range, major bleeding, and thrombo-embolic complications from the national quality registry AuriculA.

Aims In anticoagulation treatment with warfarin, the risk of thrombo-embolic events must be weighed against the risk of bleeding. Time in therapeutic range (TTR) is an important tool to assess the quality of anticoagulation treatment, and has been shown to correlate with less bleeding and thrombo-embolic complications. AuriculA, the Swedish national quality registry for atrial fibrillation and ant

Analysis of Channel Measurements Using a Very Large Antenna Array

Accurate wireless channel models are crucial to simulate the effect of radio wave propagation in a channel on wireless communication systems. By calculating physical processing effects that signal undergoes while traveling from transmitter to the receiver, channel models help to analyze performance of wireless systems. State of the art channel model such as WINNER and COST 2100 are able to model t

Signal and Background Studies at 8 GeV for the Light Dark Matter eXperiment

Light dark matter is a hypothesized form of dark matter in the 1 MeV to 1 GeV mass range. The Light Dark Matter eXperiment (LDMX) is an upcoming experiment to test the existence of light dark matter, by colliding an electron beam with a tungsten target and assembling a set of events that potentially indicate the existence of light dark matter. The three main detector components of the LDMX are a s

Future Electricity Consumption and Wind Power Production in Sweden - Effects of Climate Change

To maintain stability in the Swedish electricity grid, Svenska kraftnät must be able to predict future electricity production and consumption. Earlier this have been done by using historical data. Now the complexity of the system has increased, because the growing amount of electricity from non­dispatchable sources as well as the impact of climate change. Thus using only historical data will give

Cutaneous human papillomaviruses found in sun-exposed skin: Beta-papillomavirus species 2 predominates in squamous cell carcinoma

Background. A spectrum of cutaneous human papillomaviruses (HPVs) is detectable in nonmelanoma skin cancers, as well as in healthy skin, but the significance that the presence of these types of HPV DNA has for the pathogenesis of skin cancer remains unclear. Methods. We studied 349 nonimmunosuppressed patients with skin lesions (82 with squamous cell carcinomas, 126 with basal cell carcinomas, 49

Classical enterotoxins of coagulase-positive Staphylococcus aureus isolates from raw milk and products for raw milk cheese production in Ireland

Toxin-producing Staphylococcus aureus can be present in raw milk and therefore in cheese made from raw milk. To determine the number and type of toxin producers in raw milk used for raw milk cheese production in Ireland, 117 samples of raw milk and related products from five raw milk suppliers, to four raw milk cheesemakers in the South of Ireland, were analysed for coagulase positive S. aureus. E

Surveillance and Deferred Treatment for Localized Prostate Cancer. Population Based Study in the National Prostate Cancer Register of Sweden

Purpose: To what extent active surveillance and deferred treatment for localized risk prostate cancer are used is unclear. We assessed the use of surveillance and of deferred treatment in a population based, nationwide cohort in Sweden. Materials and Methods: In the National Prostate Cancer Register of Sweden, with a 98% coverage vs the compulsory Swedish Cancer Registry, we identified 8,304 incid

Psykiskt välbefinnande samt kunskap, minnen och föreställningar om bakgrunden hos internationellt adopterade vuxna med olika ankomståldrar

Vi har undersökt om det fanns några skillnader mellan vuxna, internationellt adopterades psykiska välbefinnande hos två grupper individer, antingen med tidig (ett år eller yngre) eller med sen (fyra år eller äldre) ankomstålder. Dessutom undersökte vi om det fanns några skillnader mellan gruppernas kunskap, minnen och föreställningar om bakgrunden. Individer med olika mycket kunskap, minnen och fö

Hospitalization for vascular complications in childhood onset type 1 diabetes - effects of gender and age at onset

Aims: To study the cumulative incidence of hospitalization for severe diabetic vascular complications in childhood onset type 1 diabetes patients with special regards to age at onset and gender. Methods: The Swedish Childhood Diabetes Register (SCDR) was linked to the Swedish Hospital Discharge Register up to 31 December 2004. The following diagnoses were traced: diabetic kidney disease, myocardia