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Several interactions of cytokines with extracellular matrix molecules are mediated by proteoglycans, such as biglycan and decorin. Using surface plasmon resonance, we show for the first time that tumour necrosis factor-alpha (TNF-alpha) binds to both biglycan and decorin with K(d)s of 0.81 microM and 1.23 microM respectively, a binding that was confirmed by Scatchard plots using a solid phase assa
The Zvejnieki burial ground in northern Latvia is one of the largest concentrations of burials from the Mesolithic and Neolithic in Northern Europe. The 308 burials, dominated by primary inhumation, excavated in the 1960s and 1970s have become important references for understanding the hunter-gatherer mortuary practices in the region. Recent excavations, implementing a taphonomy-focused archaeotha
An understanding of insider threats in information systems (IS) is important to help address one of the dangers lurking within organizations. This article provides a review of the literature on insider compliance (and failure of compliance) with information systems' policies in order to understand the status of IS research regarding negligent and malicious insiders. We begin by defining the terms,
The influence of different dryer fabrics on the contact coefficient has been studied experimentally under various conditions. A bench-scale drying apparatus, in which the fabric could be fixed at variable tensions, was used in the experiments. A technique for measuring the heat flux and surface temperatures of the paper sample and the hot surface was developed. Three paper grades were used in the
The General Data Protection Regulation (GDPR) establishes a right for individuals to get access to information about automated decision-making based on their personal data. However, the application of this right comes with caveats. This paper investigates how European insurance companies have navigated these obstacles. By recruiting volunteering insurance customers, requests for information about
The prothrombin gene G20210A mutation and the platelet glycoprotein IIIa polymorphism PlA2 have been shown to be associated with thromboembolic disease. We wondered if mutations were overrepresented in patients with central retinal vein occlusion. We studied 129 consecutive patients with a history of central retinal vein occlusion. We analysed for the prothrombin gene G20210A mutation and the plat
Portugal's real income per head grew by a factor of eight during the second half of the twentieth century, a period of fast convergence towards Western European living standards. We use a new sample of about 3,400 infants and children living in Lisbon to document trends in the prevalence of stunting and wasting between 1906 and 1994. We find that stunting and wasting fell quickly from around 1950,
We measured a set of π±Σ∓, π0Σ0, and π−Σ0 invariant mass spectra below and above the K¯N mass threshold in K−-induced reactions on deuteron. The measured πΣ mass spectral shape is well reproduced via the two-step mechanism, i.e., a neutron knocked out at a forward angle from a deuteron by an incident K−, with the K¯ recoiled backward reacting with the residual nucleon to produce π and Σ. We deduce
Nonlinear optical response of Au metallic nanoparticles, synthesized and embedded in sapphire by using ion implantation, as a function of their size and shape is studied. The size of the Au NPs was varied by controlling the annealing time of the gold-irradiated sapphire in a reducing atmosphere. Their shape was changed from approximately spherical to prolate by swift heavy-ion irradiation using Si
We systematically fabricate devices and analyse data for vertical InAs/(In)GaAsSb nanowire Tunnel Field-Effect Transistors, to study the influence of source dopant position and level on their device performance. The results show that delaying the introduction of dopants further in the GaAsSb source segments improved the transistor metrics (subthreshold swing and the ON-current performance), due to
Of concern is the fractional Kadomtsev–Petviashvili (fKP) equation and its lump solution. As in the classical Kadomtsev–Petviashvili equation, the fKP equation comes in two versions: fKP-I (strong surface tension case) and fKP-II (weak surface tension case). We prove the existence of nontrivial lump solutions for the fKP-I equation in the energy subcritical case α>45 by means of variational method
