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Light pipes offer a passive way to bring daylight inside deep buildings, such as agricultural buildings. However, the lack of reliable performance predictability methods for light pipes represents a major obstacle preventing their widespread use. This paper evaluates a simulation approach for performance prediction and identifies key light pipe design parameters affecting their daylight transmissi
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Hydroquinone glycosides were produced by transglycosylation reactions catalyzed by cyclodextrin glucanotransferase (CGTase) from Thermoanaerobacter sp. (Toruzyme (R) 3.0L). The reactions were carried out in an aqueous system containing hydroquinone (HQ) and maltodextrin as acceptor and donor substrate molecules respectively. The conditions for the synthesis of hydroquinone glucoside (alpha-arbutin
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Ischemic heart disease is the leading cause of death in high-income parts of the world and is caused mainly by atherosclerosis in the coronary arteries. The rupture of an atherosclerotic plaque with subsequent platelet activation and clot formation can lead to myocardial infarction (MI). Atherosclerosis is a complex process, which involves the accumulation and oxidation of low-density lipoprotein
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A candidate for chiral bands was found in Tl-198 for the first time in a mass region of oblate (or nonaxial with gamma >= 30 degrees) deformed nuclei. Two bands show very similar quasiparticle alignments, moments of inertia, and B(M1)/B(E2) ratios. They have a relative excitation energy of about 500 keV and different patterns of energy staggering. Calculations using the two-quasiparticle-plus-tria
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The uncertainty in eddy covariance (EC) flux measurements is assessed for CH4 and N2O using data measured at a dairy farm site in the Netherlands in 2006 and 2007. An overview is given of the contributing uncertainties and their magnitude. The relative and absolute uncertainty of a 30 min EC flux are estimated for CH4 and N2O using N = 2185 EC fluxes. The average absolute uncertainty and its stand
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Noroviruses (formerly Norwalk-like viruses) are a major cause of acute gastroenteritis worldwide and are associated with a significant number of nosocomial and food-borne outbreaks. In this study we show that the human secretor FUT2 gene, which codes for an alpha(1,2)-fucosyltransferase synthesizing the H-type 1 antigen in saliva and mucosa, is associated with susceptibility to norovirus infection
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Northern Europe was capped by ice during Weichsel (Wurm), the maximum of which occurred approximately 18,000 years before present. When in the latter part of the 19(th) century the view of an all-devastating land ice (the tabula rasa hypothesis) was generally adopted by natural scientists, plant biogeographers used a simple model predicting a post-glacial, northwards re-migration of species in con
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Aims. We study the origin of tail-like structures recently detected around the disk of SU Aurigae and several FU Orionis-type stars. Methods. Dynamic protostellar disks featuring ejections of gaseous clumps and quiescent protoplanetary disks experiencing a close encounter with an intruder star were modeled using the numerical hydrodynamics code FEOSAD. Both the gas and dust dynamics were taken int
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Importance: Neuroprognostication studies are potentially susceptible to a self-fulfilling prophecy as investigated prognostic parameters may affect withdrawal of life-sustaining therapy. Objective: To compare the results of prognostic parameters after cardiac arrest (CA) with the histopathologically determined severity of hypoxic-ischemic encephalopathy (HIE) obtained from autopsy results. Design,
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Objectives. Chest pain is a common complaint in the emergency department (ED), and it is a challenge to identify low-risk chest pain patients eligible for early discharge. We aimed to develop a simple objective decision rule to exclude 30-day major adverse cardiac events (MACE) in ED chest pain patients. Design. We analyzed prospectively included patients presenting with chest pain. Low risk patie
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High resolution 100 kV electron beam lithography in thin layers of the negative resist SU-8 is demonstrated. Sub-30 nm lines with a pitch down to 300 nm are written in 100 nm thick SU-8. Two reactive ion etch processes are developed in order to transfer the SU-8 structures into a silicon substrate, a Soft O-2-Plasma process to remove SU-8 residues on the silicon surface after development and a hig
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UNLABELLED: To clarify the role of the TNFRSF11B gene encoding osteoprotegerin (OPG), in Paget's disease of bone (PDB) we studied TNFRSF11B polymorphisms in an association study of 690 UK subjects and in a worldwide familial study of 66 kindreds. We found that the G1181 allele of TNFRSF11B, encoding lysine at codon 3 of the OPG protein, predisposes to both sporadic and familial PDB.INTRODUCTION: P
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The purpose of this studywas to investigate the prognostic value of lactate at admission, 12-h lactate and 12-h lactate clearance for 30-day survival in comatose patients admitted after out of hospi tal cardiac Arrest (OHCA). Although measures of lactate have been successfully implemented in sepsis and trauma care, most OHCA studies are biased due to design and the results are conflicting. This is
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BACKGROUND: Pre-treatment with unfractionated heparin is common in ST-segment elevation myocardial infarction (STEMI) protocols, but the effect on intracoronary thrombus burden is unknown. We studied the effect of heparin pre-treatment on intracoronary thrombus burden and Thrombolysis in Myocardial Infarction (TIMI) flow prior to percutaneous coronary intervention in patients with STEMI.METHODS: T
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An area and power efficient high-throughput VLSI implementation of a 4 × 4, 64-QAM soft multiple-input-multiple-output (MIMO) detector, that is suitable for high-order constellation schemes is presented. The proposed MIMO detector utilizes information contained in the discarded paths to improve the bit-error-rate (BER) performance, and then reduces computational complexity using three innovative i
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The way we use computers and mobile phones today requires large amounts of processing of data streams. Examples include digital signal processing for wireless transmission, audio and video coding for recording and watching videos, and noise reduction for the phone calls. These tasks can be performed by stream programs—computer programs that process streams of data. Stream programs can be composed
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Importance: Mitochondrial disease is being diagnosed with increasing frequency. Although children with mitochondrial disease often have severe, life-limiting illnesses, many survive into adulthood. There is, however, limited information about the impact of mitochondrial disease on healthcare utilization in the U.S. across the lifespan. Objectives: To describe the characteristics of inpatient hospi
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Background: Manganese (Mn) is an essential metal that can become neurotoxic at elevated levels with negative consequences on neurodevelopment. We have evaluated the influence of single nucleotide polymorphisms (SNPs) in Mn transporter genes SLC30A10 and SLC39A8 on Mn concentrations in dentine, a validated biomarker that reflects Mn tissue concentrations early in life. Methods: The study included 1
