Filtyp
To cite this article: Schlehofer B, Siegmund B, Linseisen J, Schüz J, Rohrmann S, Becker S, Michaud D, Melin B, Bas Bueno-de-Mesquita H, Peeters PHM, Vineis P, Tjonneland A, Olsen A, Overvad K, Romieu I, Boeing H, Aleksandrova K, Trichopoulou A, Bamia C, Lagiou P, Sacerdote C, Palli D, Panico S, Sieri S, Tumino R, Sanchez M-J, Rodriguez L, Dorronsoro M, Duell EJ, Chirlaque M-D, Barricarte A, Borgq
In their quest for a more efficient and effective utilization of the resources allocated to engineering design projects, and thus to the overall product development project from which the current design task(s) originate, an increasing number of companies allow engineering designers to perform Computer-Based Design Analysis (CBDA) on their own – CBDA is here confined to quantitative analyses using
Background: A postoperative haematoma can be a very serious complication following a neurosurgical procedure. Patients should be informed about the risks of such an event prior to surgery. From a practical point of view, it would be important to know when the patient is most likely to deteriorate and to require surgery because of a postoperative haematoma and when it might be safe to transfer the
Background and purpose Sclerostin is produced by osteocytes and is an inhibitor of bone formation. Thus, inhibition of sclerostin by a monoclonal antibody increases bone formation and improves fracture repair. Sclerostin expression is upregulated in unloaded bone and is downregulated by loading. We wanted to determine whether an anti-sclerostin antibody would stimulate metaphyseal healing in unloa
Popular Abstract in Swedish Växters artdiversitet i naturbetesmarker.Effekter av landskapsstruktur och habitathistoria. I min avhandling har jag undersökt växters artdiversitet i fragmenterade naturbetesmarker, av olika ålder och med olika historisk markanvändning. Jag har även undersökt betydelsen av habitatens isolerinsgrad i dagens och i det förflutna landskapet för dagens artdiversitet med häThe thesis examines the impact of present and past landscape structure, habitat history and management on different aspects of present-day plant species diversity in fragmented semi-natural grasslands in Sweden and in Estonia. Species diversity was significantly associated with present and/or past grassland connectivity in the majority of the studies in the thesis. However, relationships between
Carbon monoxide (CO) poisoning is a leading cause of environmental poisoning in the United States and can impair cellular metabolism through both hypoxia and direct mitochondrial toxicity, particularly via inhibition of cytochrome c oxidase (Complex IV, CIV). In this study, we performed a comprehensive assessment of the cerebral metabolic response to CO exposure in a swine model. Twenty-nine swine
Green spaces are important parts of our cities supporting both public health and providing ecosystem services such as lowering air temperature and providing stress relief. The study area, Malmö is a city in southern Sweden with a high population density. The city is largely built on and surrounded by agricultural land resulting in few naturally occurring green spaces and only planted trees. Despit
Atrial fibrillation (AF) is the most common cardiac arrhythmia worldwide, affecting an estimated 59.7 million people and imposing a growing burden on public healthcare systems. AF is characterized by a rapid and irregular heart rate. Specifically, understanding how rate-control therapies affect RR-interval variability and irregularity is essential for optimizing treatment. Accurate and reliable he
Advances in quantum computing pose a fundamental threat to classical public-key cryptosystems, including RSA and elliptic-curve cryptography (ECC), which form the foundation for authentication and key exchange in the Transport Layer Security (TLS) protocol. In response to these emerging threats, Korea launched the KpqC (Korea Post-Quantum Cryptography) project in 2021 to design, evaluate, and stan
According to Ethan Mollick, artificial intelligence (AI) is the most recent general purpose technology (GPT), the “once-in-a-generation technologies, like steam power or the internet, that touch every industry and every aspect of life” (2024, p. xv). Unlike the slowly unfolding transformations caused by these earlier GPTs, the changes sparked by AI seem to evolve daily. This rapid pace creates a s
BACKGROUND: The progression of tumor growth requires the recruitment of new blood vessels. It has been suggested that the degree of neovascularization would correlate with clinical prognosis. The purpose of the present study was to ascertain whether tumor vascularization correlated with clinical outcome in cases of primary squamous cell carcinoma of the head and neck (SCCHN).METHODS: In tumor biop
BACKGROUND: Pulmonary hypertension is a postoperative complication that may adversely affect the outcome of lung transplantation. The effect of nitric oxide (NO) inhalation on pulmonary hemodynamic indices after lung transplantation was studied and compared with findings in control pigs. METHODS: Varying concentrations of NO were inhaled by 5 pigs after left lung transplantation and right pneumone
Background: Within Europe many guidelines exist regarding the genetic testing of minors. Predictive and presymptomatic genetic testing of minors is recommended for disorders for which medical intervention/preventive measures exist, and for which early detection improves future medical health. Aim: This study, which is part of the larger 5th EU-framework "genetic education'' (GenEd) study, aimed to
Background: Therapeutic fluids used in intensive care can have profound effects on coagulation, not only by dilution itself but also by other more complicated interactions. The aim of this in vitro study was to monitor the extent of dilutive coagulopathy induced by the most common therapeutic fluids and to attempt normalization of haemostasis by fibrinogen addition. Methods: 8 patients were re
Recent technological advancements now allow us to obtain geographical position data for a wide range of animal movements. Here we used light-level geolocators to study the annual migration cycle in great reed warblers (Acrocephalus arundinaceus), a passerine bird breeding in Eurasia and wintering in sub-Saharan Africa. We were specifically interested in seasonal strategies in routes and schedules
Decomposition of organic matter in high latitude biomes makes a significant contribution to global fluxes of nutrients and carbon and is expected to accelerate due to climate change. The majority of studies have focused on decomposition during the growing season, but winter climate is expected to change dramatically. Furthermore, knowledge of the drivers of organic matter decomposition, such as li
Objective : To measure the extent to which health-related quality of life (HRQoL) in people living with HIV is associated with duration of antiretroviral therapy (ART) after controlling for sociodemographic, clinical, and other therapy-related factors. Design : Cross-sectional analysis. Methods : A gender-stratified random sample of 421 participants aged 18-64 years was selected from the patients
Measurement of cortisol concentration can contribute important information about an individual's ability to adjust to various environmental demands of both physical and psychosocial origin. However, one uncertainty that affects the possibilities of correctly interpreting and designing field studies is the lack of observations of the impact of seasonal changes on cortisol excretion. For this reason
Popular Abstract in Swedish ?DNA-mikromatriser eller genchips? är idag väletablerade verktyg inom biologisk forskning och klinisk diagnostik. Genmikromatriser kan exempelvis användas för att i mikroskala studera genetiska skillnader mellan sjuka och friska vävnader. Informationen som då erhålls kan ge värdefulla upplysningar om sjukdomens natur och användas vid utveckling av nya läkemedel. GenernAntibody-based microarrays are among the novel class of rapidly evolving proteomic technologies. In recent years, antibody microarrays have emerged as a unique tool for high-throughput protein expression profiling with great promise within biomedicine and a wide range of potential applications, including disease diagnostics and biomarker discovery. In order to evolve the technology from small dedi
Popular Abstract in Swedish Helicobacter pylori är en spiralformad Gramnegativ human-specifik patogen, som kan penetrera magsäckens slemlager och kolonisera epitelskiktet. H. pylori infektion är en högriskfaktor för utvecklandet av kronisk gastrit, magsår och ventrikelcancer. Både aktivt växande spiralformer av H. pylori och dess runda viloformer framkallar kronisk magkatarr (gastrit) i BALB/cA möHelicobacter pylori is a human pathogen strongly associated with chronic type B gastritis, peptic ulcer disease, gastric cancer and MALT lymphoma. Our aims were to establish a mouse model of H. pylori infection, to study pathogenesis of gastritis and gastric cancer and to investigate new treatment strategies in this model. Both spiral and coccoid forms of H. pylori strains 17874, 25 and 553/93 cau
