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Inbred lymphopenic, diabetes-prone (DP) and non-lymphopenic, diabetes-resistant (DR) BB rats in a specific pathogen-free (SPF) colony were subjected to a cross-intercross breeding experiment which showed diabetes to segregate as a recessive trait. All DP rats, but none of the DR and F1 rats, developed diabetes. In contrast, about 25% of the F2 rats developed diabetes which made it possible to stud
OBJECTIVE: To investigate possible associations between socioeconomic status, occupation, and hospitalization for rheumatoid arthritis (RA).METHODS: A nationwide database was constructed by linking the Swedish Census to the Hospital Discharge Register in order to obtain data on all first hospitalizations for RA in Sweden during the study period 1964 to 2004. Standardized incidence ratios (SIR) and
This study compared the cytokine production of uroepithelial cell lines in response to gram-negative bacteria and inflammatory cytokines. Human kidney (A498) and bladder (J82) epithelial cell lines were stimulated with either Escherichia coli Hu734, interleukin 1α (IL-1α), or tumor necrosis factor alpha (TNF-α). Supernatant samples were removed, and the RNA was extracted from cells at 0, 2, 6, and
Human cystatin C variants in which the evolutionarily conserved Gly-11 residue has been replaced by residues with positively charged (Arg), negatively charged (Glu), bulky hydrophobic (Trp), or small (Ser or Ala) side-chains have been produced by site-directed mutagenesis and expression in Escherichia coli. The five variants were isolated and structurally verified. Their inhibitory properties were
Objective To examine the safety and efficacy of endovascular management of isolated infrarenal aortic occlusive disease within our centre. Design and methods Retrospective analysis of all patients who underwent endovascular treatment of occlusive disease that is confined to the infrarenal aorta between September 1993 and November 2004. Results Primary aortic stenting was carried out in 16 wom
Background: p21-activated kinase 1 (Pak1) phosphorylates many proteins in both normal and transformed cells. Its ability to phosphorylate and thereby activate the estrogen receptor alpha (ER alpha) potentially limits the effectiveness of antiestrogen treatment in breast cancer. Here we studied associations between Pak1 expression and subcellular localization in tumor cells and tamoxifen resistance
This second digital edition includes my research from 2013 until November 2015. There are many important changes from de first version. This version introduces the Technocratic Mode of Production based on the exploitation of the consumers. It includes a complete description of the cyborg society as it is today, the new castes that constitute it and the economic acts that regulate the new Mode of P
Electron mean free path (MFP) was determined by the angular resolved photoemission in 10-40 eV energy range for GaAs(100)-c(4 x 4) by the overlayer method. The investigation was based on the attenuation of the normal photoemission intensity of the Al 2p line from the molecular-beam-epitaxy grown GaAlAs layer buried four monolayers of GaAs below the surface. The energy dependence of the MFP shows a
Milk is rich in miRNAs that appear to play important roles in the postnatal development of all mammals. Currently, two competing hypotheses exist: the functional hypothesis, which proposes that milk miRNAs are transferred to the offspring and exert physiological regulatory functions, and the nutritional hypothesis, which suggests that these molecules do not reach the systemic circulation of the mi
BACKGROUND: The detection of prodromal Parkinson's disease (PD) is desirable to test drugs with neuroprotective potential, but will be affected by known disease variations.OBJECTIVE: To assess the prevalence of four key non-motor prodromal PD markers, and evaluate the sensitivity of case detection when non-motor screening tools for prodromal PD are implemented in an early clinical PD cohort.METHOD
Denna artikel innehåller en analys av samtliga rapporter från Statens offentliga utredningar (SOU), 1945-89. Analysen applicerar metoder inom digital humaniora och inkluderar forskning gjort i en Jupyterlabbmiljö som utvecklats på Humlab på Umeå universitet. Artikeln är ett resultat av forskningsprojektet Välfärdsstaten analyserad, som ämnar att digitalisera litteratur, arbetar med datasäkring av In 2015 the National Library of Sweden finished digitising all Governmental Official Reports (SOU) from 1922 to 1999. Traditionally, SOU reports – and work performed within different governmental committees – were tasked with preparing the Swedish government for apt and rational decision-making. The range of subjects covered by governmental committees and SOU reports basically includes every area
BACKGROUND: Electronic health records (EHRs) are generated at an ever-increasing rate. EHR trajectories, the temporal aspect of health records, facilitate predicting patients' future health-related risks. It enables healthcare systems to increase the quality of care through early identification and primary prevention. Deep learning techniques have shown great capacity for analyzing complex data an
Atrial fibrillation (AF) is the most common arrhythmia in the world, leading to a significant burden to patients and the healthcare system. It is characterised by rapid and irregular atrial contractions stemming from disorganised electrical activity in the atria. The atrioventricular (AV) node regulates heart rate during AF by filtering electrical impulses from the atria.However, for persistent AF
Synucleinopathies are neurodegenerative disorders characterized by intracellular protein aggregates, progressive neurodegeneration, and neuroinflammation. Alpha-synuclein (a-syn) is the principal component of intracellular aggregates and can be modified by several mutations and post-translational modifications (PTMs), which can alter the protein structure affecting its aggregation, toxicity, and a
Background: Vascular adverse events after collagenase injection for Dupuytren disease are absent in large trials and systematic reviews. The aim of this study is to present a case series of delayed vascular complications after collagenase treatment. Methods: A prospective evaluation of 1181 consecutively treated patients at one orthopedic department identified three patients reporting symptoms of
1 Strategi- och kvalitetsdokument INSTITUTIONEN FÖR PSYKOLOGI 2016-12-13 2 VISION Vår vision är en institution som genom forskning och utbildning inom den psykologiska disciplinen förstår, förklarar och för- bättrar vår värld och män- niskors villkor i samverkan med omvärlden och det samhälle vi lever och verkar i. 3 Forskning Forskningsmål • Institutionen för psykologi skall vara en aktiv forskni
https://www.psy.lu.se/en/sites/psy.lu.se.en/files/strategidokument3.pdf - 2026-07-09
Schedule_SWEAHCourse_2018_add Department of Psychology 1 (2) Haraldsgatan 1, PO Box 500, SE 405 30 Gothenburg, Sweden +46 31 786 00 00 www.psy.gu.se Gerontology – multidisciplinary and integrative perspectives on aging 5 (3+2) higher education credits Third cycle Content The first course module (3 HEC) presents current research in biological, medical/geriatric, health sciences, psychological, soci
https://www.sweah.lu.se/en/sites/sweah.lu.se.en/files/information_gerontologycourse_2018.pdf - 2026-07-09
10 0 år m ed N ils H ol ge rs so n En ny läsebok Den reformivrande fackorganisationen Sveriges allmänna folkskollärareförening tillsatte i januari 1901 en kommitté för att få fram en modern läsebok. Initiativtagare var Fridtjuv Berg och överlärare Alfred Dalin. Den senare önskade att boken fick en ”folklig svensk stämning alltige- nom, så att barnens bästa och vackraste intryck från det svenska he
https://www.ub.lu.se/en/sites/ub.lu.se.en/files/2006_nils_holgersson_100_ar.pdf - 2026-07-09
