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Popular Abstract in Swedish För att en organism ska fungera är det nödvändigt att alla de celler som bygger upp organismen kommunicerar med varandra. Denna kommunikation sker genom att speciella proteiner på cellens yta, s.k. receptorer, tar emot signaler från andra celler. G-proteinkopplade receptorer (GPCR) är den vanligaste typen av receptorer. Då en signalmolekyl binder till en GPCR ändrar de

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Context Small single-center studies have shown that cerebrospinal fluid (CSF) biomarkers may be useful to identify incipient Alzheimer disease (AD) in patients with mild cognitive impairment (MCI), but large-scale multicenter studies have not been conducted. Objective To determine the diagnostic accuracy of CSF beta-amyloid(1-42) (A beta 42), total tau protein (T-tau), and tau phosphorylated at po

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This thesis is an empirical and theoretical exploration of the surprising finding that people often may fail to notice dramatic mismatches between what they want and what they get, a phenomenon my collaborators and I have named choice blindness. The thesis consists of four co-authored papers, dealing with different aspects of the phenomenon. Paper one presents an initial set of studies using a co

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Low body mass index (BMI) is a well-documented risk factor for future fracture. The aim of this study was to quantify this effect and to explore the association of BMI with fracture risk in relation to age, gender and bone mineral density (BMD) from an international perspective using worldwide data. We studied individual participant data from almost 60,000 men and women from 12 prospective populat

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Popular Abstract in Swedish Denna avhandling handlar om hur företag visar, och kan visa, miljöhänsyn vid upphandling av godstransporttjänster. Transporter är en starkt bidragande, och växande, faktor till många miljöproblem såsom den förstärkta växthuseffekten och hälsofarliga partiklar i luften. Behovet av transporter ökar ständigt till följd av exempelvis lokalisering av produktion till låglöneThe logistical activity of transport is one of the largest contributors to several environmental problems. One efficient and effective way to decrease the environmental impact from transports is to implement changes in the logistically related strategies and activities applied, such as the selection of transport suppliers. Consideration of the environmental aspect when purchasing transport servic

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Objective. Heredity is a major cause of ovarian cancer and during recent years the contribution from germline mismatch repair (MMR) gene mutations linked to Lynch syndrome has gradually been recognized. Methods. We characterized clinical features, tumor morphology and mismatch repair defects in all ovarian cancers identified in Swedish and Danish Lynch syndrome families. Results. In total, 63 epit

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High spectral resolution (0.004 cm(-1)) infrared solar absorption measurements Of CO, C2H6, and HCN have been recorded with the Fourier transform spectrometer located at the Network for the Detection of Stratospheric Change complementary station at the University of Wollongong, Australia (34.45 degreesS, 150.88 degreesE, 30 m above sea level). The time series covers March 1997 to February 1998. Pr

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Popular Abstract in Swedish Den här avhandlingen handlar om studenter som samtalar och samarbetar i små grupper i en nätbaserad kurs. Studien har ett intresse av att beskriva och förstå de dialogiska processer, som uppstår i ett autentiskt nätbaserat samtal, vilket pågår under lång tid. Det handlar bland annat om att studera, hur deltagarna använder sig av de meningserbjudande, i form av deltagarnThis thesis investigates students' dialogue and collaboration when working in small groups in a netbased course. The aim is to describe and shed light on student's dialogue and collaboration in a computer-mediated communication working with a problem oriented task. Thus, the interest lies in student's engagement in the learning situation rather than on the learning outcomes. The research was carr

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Popular Abstract in Swedish I avhandlingen "Dynamisk dialog: en analytisk och konstruktiv studie av den religiösa kommunikationens problem på grundval av Martin Bubers dialogfilosofi" studerar jag olika aspekter av Bubers modell för hur en människa meningsfullt kan kommunicera sin religiösa upplevelse till och med en annan människa. Min metod har både en begreppsanalytisk och en fenomenologisk sidIn the present work, I study various aspects of Martin Buber's model of how a human being can communicate, in a meaningful way, his or her religious experiences to and with another human being. My method has aspects of both conceptual analysis and phenomenologial description. I focus on the individual partners, their mutual relationships and the religious message. Buber's model is based on the con

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Popular Abstract in Swedish Kalcium är ett livsviktigt ämne för både djur och växter. Kalcium behövs t.ex. för uppbyggnaden av skelettet, för att hjärtat skall slå och för att musklerna skall dras samman. I växter är kalcium en viktig beståndsdel i cellväggarna och behövs också vid bl.a. celldelning. Trots detta måste koncentrationen av fria kalciumjoner inne i cellen (i cellvätskan) hållas mycket

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Objective: The purpose of the study was to compare in prospective randomized fashion a manually sutured esophagogastric anastomosis in the neck and a stapled in the chest after esophageal resection and gastric tube reconstruction. Summary Background Data: Despite the fact that all reconstructions after esophagectomy will result in a cervical or a thoracic anastomosis, controversy still exists as t

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At Forsmark, ca. 120 km north of Stockholm in central Sweden, ductile high-strain belts with WNW to NW trend anastomose around tectonic lenses with an inferred lower degree of ductile strain. Previous studies of ductile deformation zones with WNW to NW trend, elsewhere in the western part of the Svecofennian orogen in central Sweden, have yielded estimates for the timing of at least one phase of d

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At the University Hospital of Malmo, Sweden, standardized trauma charts were used for registration of all jaw fractures from 1972 to 1976. During the year 2005 the aim was to interview all patients treated non-surgically for unilateral mandibular condylar fractures during this period. In total, 49 patients with unilateral condylar fractures were treated non-surgically in 1972-1976. Of these, 23 pa

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Extensive measurements of soil surface (including vegetation cover) CO2 efflux were carried out on 80 positions at four different forest sites (Sweden, Germany, Czech Republic and Italy) using a closed dynamic chamber technique. The period of measurement was 4-5 consecutive days per site. Two approaches were used to analyze the measured data, the Q(10) parameter and the Arrhenius relationship. Bas

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From a control design point of view, modern diesel engines are dynamic, nonlinear, MIMO systems. This paper presents a method to find low-complexity black-box dynamic models suitable for model predictive control (MPC) of NOx and soot emissions based on on-line emissions measurements. A four-input-five-output representation of the engine is considered, with fuel injection timing, fuel injection dur

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Epithelial ovarian cancer (EOC) is the most lethal malignancy of the female reproductive tract. Due to vague symptomatology, the majority of EOC patients are diagnosed in advanced clinical stages with poor survival rates, despite improvements in surgical techniques and the advent of targeted therapeutics. Hence, there is an urgent need to identify novel biomarkers of early diagnosis, prognosis and

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Unusually high CO2 concentrations were frequently observed during stable nights in late summer 2006 at the CarboEurope-Integrated Project (CEIP) forest site in Norunda, Sweden. Mean CO2 concentrations in the layer below the height of the eddy-covariance measurement system at 30 m reached up to 500 mu mol mol(-1) and large vertical and horizontal gradients occurred, leading to very large advective

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Popular Abstract in Swedish Diabetes mellitus, kronisk njursjukdom samt aterosklerotisk hjärtsjukdom utgör de vanligaste orsakerna till hjärt-kärlsjukdom och för tidig dödlighet. Dessa sjukdomar har blivit ett stort världsomfattande hälsoproblem med ökande prevalens och incidens. Tidig identifiering av patienter som ligger i riskzonen for komplikationer, framförallt hjärt-kärl komplikationer, tordRisk stratification of patients with chronic kidney disease and atherosclerotic heart disease is crucial. Microalbuminuria (MA) is associated with an increased risk of kidney and cardiovascular (CV) death, especially in patients with diabetes. However, MA in many instances is not sensitive for disease outcome; for instance, not all diabetic patients with albuminuria progress to kidney failure, and

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Wetlands are valuable ecosystems, and assets for human life, that must be regularly monitored, starting with accurately mapping their location and extent. However, an updated national inventory of wetlands is needed. The availability of multi-source data, and advanced machine learning algorithms in Google Earth Engine (GEE) offers excellent opportunities to map wetlands on a country-wide scale. Th

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Detta examensarbete behandlar den svenska regleringen för framtidsfullmakter. Uppsatsen har ett fokus på möjlig praktisk problematik vid författandet och nyttjandet av dessa. Syftet med uppsatsen har varit en fördjupning i de bakomliggande motiven till lagstiftningen samt de praktiska effekterna av hur Lag (2017:310) om framtidsfullmakter är implementerad i svensk rätt. Uppsatsen besvarar fyra fråThis thesis deals with the Swedish regulations for future powers of attorney. The essay has a focus on possible practical problems in the writing and use of these. The purpose of the essay has been an in-depth look at the underlying motives for the legislation as well as the practical effects of how the act (Lag (2017:310) om framtidsfullmakter is implemented in Swedish law. The essay answers four