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Immuno-proteomic screening has identified several tumor-associated autoantibodies (AAb) that may have diagnostic capacity for invasive epithelial ovarian cancer, with AAbs to P53 proteins and cancer-testis antigens (CTAGs) as prominent examples. However, the early detection potential of these AAbs has been insufficiently explored in prospective studies. We performed ELISA measurements of AAbs to C
The full Holocene development of the large (8100 km(2)) Vatnajokull ice cap in Iceland with its many outlet glaciers is poorly known. The idea of an early deglaciation, leading to a glacier-free period in mid-Holocene, followed by the Neoglaciation is still the main concept for the glacial history in the North Atlantic region, including Iceland. We have examined a continuous sediment record from t
Invasive exotic plant species often have fewer natural enemies and suffer less damage from herbivores in their new range than genetically or functionally related species that are native to that area. Although we might expect that having fewer enemies would promote the invasiveness of the introduced exotic plant species due to reduced enemy exposure, few studies have actually analyzed the ecologica
Recent research on the process of biological phosphorus removal in lab-scale treatment systems has indicated that: (i) the development of an actively poly?-accumulating bacterial community after the introduction of an anaerobic period may take at least 4 months; (ii) up to 80% of all aerobic bacteria isolated from these communities are able to accumulate polyP; (iii) polyP synthesized by the bacte
Background: In many parts of the world, roadsides are regularly managed for traffic-safety reasons. Hence, there are similarities between roadsides and certain other managed habitats, such as wooded pastures and mown or grazed grasslands. In contrast to roadsides, the latter habitats have declined rapidly in Europe during the last century, and today only a fraction of their former extent remains.
This paper provides a regional, empirical analysis of policy portfolios that aim to contribute towards a ‘Green Energy Economy’ (GEE) transformation. Taking green economy policies and related indicators as the analytical framework, the study examines (i) the composition of policy portfolios promoting low-carbon energy technologies, (ii) short-term trends related to the GEE, (iii) long-term empiric
The development of the compound eyes and nervous system of the penaeid shrimp,Penaeus duorarum, from the first nauplius to the first postlarva, has been studied. The first anlage of the compound eyes is a pair of optic discs on the front of the animal. These increase in size through cell-division until the second protozoea stage, where the eye-stalks appear with ommatidia and optic neuropiles deve
The macro- and micro-features of bone can be assessed by using imaging methods. However, nano- and molecular features require more detailed characterization, such as use of e.g., vibrational spectroscopy and X-ray scattering. Nano- and molecular features also affect the mechanical competence of bone tissue. The aim of the present study was to reveal the effects of mineralization and its alteration
Prostate cancer is the second most common diagnosed cancer among men. Currently there are no reliablebiomarkers to distinguish between indolent and aggressive disease. When men progress to advanced stages of the disease treatment options are limited and resistance to treatments available today is a growing problem. Recently the signal transducer and activator of transcription 3 (STAT3) has been su
Background Iterative reconstruction (IR) is a recent reconstruction algorithm for computed tomography (CT) that can be used instead of the standard algorithm, filtered back projection (FBP), to reduce radiation dose and/or improve image quality. Purpose To evaluate and compare the image quality of low-dose CT of the lumbar spine reconstructed with IR to conventional FBP, without further reduction
We report a new paleomagnetic pole for the Black Range Dolerite Suite of dykes, Pilbara craton, Western Australia. We replicate previous paleomagnetic results from the Black Range Dyke itself, but find that its magnetic remanence direction lies at the margin of a distribution of nine dyke mean directions. We also report two new minimum ID-TIMS 207Pb/206Pb baddeleyite ages from the swarm, one from
Aims: Patterns of species richness, such as the remarkable biodiversity of tropical regions, have been documented and studied for centuries. However, their underlying evolutionary and ecological causes are still incompletely understood. A commonly stated paradigm in the literature is that high richness in some habitats is directly caused by one of three competing explanations: (1) greater time-for
The present study was designed to address two questions. First, can an intrastriatal neural allograft exhibit long-term survival (18 weeks) if the host is immunized by an orthotopic skin graft 6 weeks after neural transplantation (the 6w-Long group)? Second, can an intrastriatal neural allograft survive when the host is challenged by an orthotopic skin allograft either simultaneously (Sim) with th
Objective To examine trends in rheumatoid arthritis (RA) as an underlying cause of death (UCD) in 31 countries across the globe during 1987-2011. Methods Data on mortality and population were collected from the World Health Organization mortality database and the United Nations. Age-standardized mortality rates (ASMR) were calculated by means of direct standardization. We applied joinpoint regress
The rapid expansion of oil palm is a major driver of deforestation and other associated damage to the climate and ecosystem in tropical regions, especially Southeast Asia. It is therefore necessary to precisely detect and monitor oil palm plantations to safeguard the ecosystem services and biodiversity of tropical forests. Compared with optical data, which are vulnerable to cloud cover, the Sentin
BACKGROUND: Optimal care for children with HIV infection includes timely assessment of treatment failure. Using HIV viral load to define treatment failure remains a challenge in resource-limited settings.METHODS: Children with HIV infection who were already on or starting first-line antiretroviral therapy were enrolled and followed over time. We examined clinical and immunologic predictors of viro
For the past 30 to 40 years, well before the concept of sustainable development became politically correct, regulation of the environment has been covered by Environmental Protection Agencies worldwide. Perhaps one of the most important things that we have learned is that regulations have significant costs, not just benefits, and that analysis of the cost and benefit of proposed rules is an indisp
Aims: Peripheral artery disease (PAD) constitute a high-risk with adverse clinical outcomes. We aimed to investigate the cardiovascular outcomes following myocardial infarction (MI). Methods and results: This nationwide, Danish register-based follow-up study includes all patients experiencing an MI between 2000 and 2017. Patients with and without PAD were compared. Multivariable logistic regressio
Objective: To correlate clinical outcomes to pathology in SARS-CoV-2 infected placentas in stillborn and liveborn infants presenting with foetal distress.Design: Retrospective, observational.Setting: Nationwide.Population or sample: Five stillborn and 9 liveborn infants from 13 pregnant women infected with SARS-CoV-2 seeking care at 7 different maternity units in Sweden.Methods: Clinical outcomes
At Forsmark, ca. 120 km north of Stockholm in central Sweden, ductile high-strain belts with WNW to NW trend anastomose around tectonic lenses with an inferred lower degree of ductile strain. Previous studies of ductile deformation zones with WNW to NW trend, elsewhere in the western part of the Svecofennian orogen in central Sweden, have yielded estimates for the timing of at least one phase of d
