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Immature progenitor cells (generated by in vitro propagation) may provide a useful alternative to primary cells (from dissected embryonic tissue) for transplantation if their migratory and proliferative and differentiation properties can be controlled and directed in vivo. In this study E15 murine EGF-responsive progenitor cells were transplanted to the striatum of adult rats. Simultaneously, thes
Dynamic artery blood pressure (Finapres) response to active standing up, normally consisting of initial rise, fall and recovery above the baseline (overshoot), was compared with the early steady-state artery blood pressure level to measure sympathetic vasomotor function in healthy subjects (n = 23, age 35 +/- 9 years; mean +/-SD) and in type I diabetic patients without autonomic neuropathy (AN) (g
The effect of pixel size on shape determination in screening digital mammography systems was studied using a shape identification task as the measured outcome. Ten microcalcifications on screen-films were digitised to a range of pixel sizes (2.5-200 μm) and extracted from computed radiography (CR) images (50 μm) acquired under equivalent imaging conditions. Fifteen observers attempted to identify
Absorption, reflection and emission polarization spectra of CdWO4 crystals have been studied in the region 3.5-30 eV in order to distinguish the excitonic and electron-hole processes in the vicinity of the band gap. The following parameters have been defined from the Urbach tail study at 6-300 K: E-0 = 5 eV, sigma(0) = 0.31, homega = 70 meV (565 cm(-1)). Excitonic processes have been shown to domi
Rubidium concentrations in tissues of organisms (vascular plants, fungus, insect, bird, rodents) were closely related to soil chemical properties (K+ saturation as % cation exchange capacity, and pH) at repeated sampling of 30 beech forest sites in south Sweden. The Rb+ concentration of organisms, representing a variety of tropic levels, was a sensitive measure of the K+ status of acid soil ecosys
A novel insertion device for electron storage rings, called the MAX-Wiggler [Nucl. Instr. and Meth. A 467-468 (2001) 118], has been constructed at MAX-lab. The MAX-Wiggler is a cold bore superconducting wiggler magnet with 47,3.5 T poles and a period length of 61 mm. It is designed for the production of X-rays at the 1.5 GeV electron storage ring MAX-II [Nucl. Instr. and Meth. A 343 (1994) 644] at
An analytical model is developed to calculate recession distance and eroded volume for coastal dunes during severe storms. The transport relationship used in the model is based on wave impact theory, where individual swash waves hitting the dune face induce the erosion. Combining this relationship with the sediment volume conservation equation describes the response of the dune to high waves and w
Results from a Monte Carlo investigation are presented for the application of the dual photopeak window (DPW) scatter correction method to phantom geometries of varying shapes, sizes, and densities as well as to several collimators. A Monte Carlo program was used to simulate a Tc-99m point source at locations of 0.5 cm from the phantom surface, at the center, 0.5 cm from the bottom, and 4/5 the di
Popular Abstract in Swedish Tillväxthormon (GH) insöndras stötvis från hypofysen. Insöndringen är som högst nattetid, och de högsta nivåerna ses under puberteten för att därefter avta succecivt med ökande ålder. En av de vanligaste orsakerna till brist på GH är godartade tumörer i hypofys och hypofysnära områden där även behandling med kirurgi och strålbehandling kan bidra till hypofysinsufficiensIn childhood onset growth hormone deficiency (GHD) a reduction in cardiac left ventricular mass (LVMi) and impairment of cardiac systolic function, as well as in glomerular filtration rate (GFR) has been shown. In study I, we showed that a low dose of GH treatment for 10 months resulted in increased LVMi and kidney size. No significant improvement in cardiac systolic function or GFR, except for a
A group of Swedish radiation oncologists and hospital physicists have estimated the number of patients in Sweden suitable for proton beam therapy in a facility where one of the principal aims is to facilitate randomized and other studies in which the advantage of protons can be shown and the magnitude of the differences compared with optimally administered conventional radiation treatment, also in
To investigate whether recurrent purulent otitis media results in permanent hearing loss, we studied 2 subgroups of children from a cohort, earlier prospectively followed from birth to the age of 3 years. One subgroup had recurrent acute otitis media (n = 12). and the other had no acute otitis media at all ("healthy" children; n = 21). At follow-up of these subgroups at the age of 10. no child had
This work describes the use of focused, high-intensity light from a Ti: sapphire laser that generates femtosecond pulses to irradiate mixture of CeO2 and Tb4O7 under ambient conditions. The prepared samples were investigated by means of X-ray diffraction (XRD), X-ray photoelectron spectroscopy (XPS) and scanning electron microscope (SEM). XRD and XPS measurement results demonstrated that solid sol
Estrogen and progesterone are key regulators of normal breast epithelial cell proliferation and differentiation. They are also involved in the initiation and progression of breast tumorigenesis. Several experimental studies have demonstrated that steroid hormones affect cell cycle proteins associated with tumor initiation and progression. Hormone replacement therapy (HT) is widely used to alleviat
Needle stimulation (acupuncture) has recently been shown to increase blood flow in the tibialis anterior muscle and overlying skin in healthy subjects (HS) and patients with fibromyalgia (FM). The aim of the present study was to examine the effect of needle stimulation on local blood flow in the trapezius muscle and overlying skin in HS and two groups of patients suffering from chronic pain in the
ZnWO4, ZnWO4 : Fe and ZnWO4 : Mo crystals were investigated by the methods of time-resolved spectroscopy in the temperature range of 4.2-300 K. It is shown that the Mo and Fe impurities significantly reduce the light yield of ZnWO4. The main 2.5 eV emission of ZnWO4 and the 1.77 eV emission band of ZnWO4 : Mo are shown to originate from the triplet excited state of the WO6 and MoO6 complex, respec
The rates of positive tuberculin skin test (TST) reactions and BCG scarring after BCG vaccination vary between studies and populations. Tuberculin reactivity and BCG scarring may be related to better child survival in low-income countries. We therefore studied determinants for TST reaction and scarring in Guinea-Bissau. In a cohort of children born in suburban Bissau from March 2000 to July 2002,
Two bypassing agents are currently available to circumvent the need for factor FVIII in hemophilia A patients with inhibitors: the activated prothrombin complex FEIBA VH and recombinant activated factor VII (NovoSeven (R)). Both products are highly effective in controlling bleeding in the presence of inhibitory alloantibodies, yet their hemostatic efficacy can be unpredictable. As the results of t
Rat dopamine D(2short) expressed in Chinese hamster ovary (CHO) cells were characterized by means of activation of [(35)S]-guanosine 5'-O-(gamma-thiotriphosphate) ([(35)S]GTPgammaS) binding and inhibition of [(3)H]raclopride binding. Among 18 dopaminergic ligands studied dopamine, NPA, apomorphine and quinpirole were full agonists in activation of [(35)S]GTPgammaS binding, while seven ligands were
The purpose of this study was to explore retina-intrinsic neuroinflammatory reactions, effects on neuronal survival, relationship with classic gliosis, and possible role of the toll-like receptor 4 (TLR4). To isolate the adult retina from the systemic immune system, a previously described large animal explant culture model was used in which full-thickness porcine retinal sheets can be kept in vitr
