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Objectives (1) To assess the risk of haematological malignancies in individuals with systemic sclerosis (SSc) compared with individuals without SSc; (2) to explore how the risk varies across groups stratified by sex and age; and (3) to determine when these malignancies present in relation to SSc diagnosis in a population-based setting. Methods We performed a nationwide cohort study using high-qual
Background: Low adherence to lipid-lowering therapy (LLT) after myocardial infarction (MI) is associated with increased risk of recurrent cardiovascular events and death. However, little is known about long-term adherence patterns following treatment interruptions. The aim of this study was to describe adherence trajectories in MI patients following a LLT treatment gap, and model the impact of dif
Background: Bioresorbable scaffolds have been associated with inferior outcomes compared to contemporary permanent metallic drug-eluting stents (DES) for percutaneous coronary intervention, particularly within the initial years after implantation; however, their long-term performance remains uncertain. This study aimed to evaluate the long-term outcomes of Swedish patients treated with Absorb bior
Background: Plasma phosphorylated tau217 (p-tau217) is a robust biomarker of Alzheimer's disease (AD) pathology. However, its full potential as a dynamic marker has still not been verified in very old persons, i.e., those with the highest incidence of AD. Objective: To examine the cross-sectional and longitudinal associations between plasma p-tau217 concentration and cerebrospinal fluid (CSF) AD b
Hard turning offers a cost-effective alternative to traditional grinding, yet the tool wear progression limits the broader industrial adoption. During hard turning, the surface microstructure of AISI 52100 steel transforms into a nanocrystalline structure known as white layer, accompanied by significant surface residual stresses. With optimal cutting conditions, surfaces develop nanocrystalline mi
Aims: Pain and poor health-related quality of life measures serve as the primary indication for primary elective total hip arthroplasty (THA). It remains challenging to predict whether THA delivers the patient-anticipated improvements. Our study aimed to develop and validate statistical and machine learning prediction models of one-year clinical improvement in patient-reported outcome measures (PR
The use of remote sensing and reanalysis weather data has not been adequately acknowledged for large-scale built environment applications, primarily regarding engineering analyses that traditionally rely on computationally expensive numerical models. This study employs a parsimonious data-driven approach concerning service life assessment of rain-exposed wooden components, enabling mapping and ass
The purpose of our master thesis is to locate and find a mathematical model of the road surface from data obtained using LiDAR measure- ments. A LiDAR is an optical instrument that generates a point cloud of its surroundings by measuring distance and intensity. Some LiDARs also generate additional metrics, but for our road model only the distance will be used. However, we will discuss how the inte
The volcano Rangitoto belongs to the Auckland volcanic field and is situated north east of Auckland city, New Zealand. The volcanos of the Auckland volcanic field have previously thought to be of monogenetic origin, but recent studies indicate that Rangitoto has a long history of eruptions, which would suggest that the volcanic system may have entered a new phase. The last eruption is dated to 500
Den informationsteknologiska utvecklingen är något utav både en frälsning och en förbannelse. Å ena sidan ser vi ett stort antal människor för vilka denna utveckling i många avseenden har underlättat deras vardag, å andra sidan ser vi hur upphovsmän och rättighetsinnehavare desperat söker att se efter sina skyddade verk och komma åt intrångsgörare. Genom informationsteknologins näst intill obegränThe development of information technology has had a two-fold effect and therefore it may be considered both a blessing and a curse. On the one hand, we see a large number of people for whom this development has facilitated them to do more in terms of their everyday life, on the other, we see authors and rightholders desperately seeking to look after their protected works and target infringers. The
Klimatförändringarna med stigande havsnivåer gör att förutsättningarna för vårt byggande måste förändras i kustnära områden. Länsstyrelsen i Skåne har fattat ett beslut om att mark under +3 meter över havet döms ut för bebyggelse. Kommunerna vid kusten får då mycket svårt att expandera, och vill därför kunna hitta eventuella lösningar för att kunna bygga i utsatta lägen. En möjlig lösning är att aWith the climate change sea levels are rising which changes the boundary conditions for sites along the coast. The County Administrative Board of Skåne has decided that new buildings should be built at least 3 meters above sea level. Because of this decision the coastal municipalities have problems with expanding further, and are really keen on finding alternative solutions in order to allow build
Modern agricultural practices give rise to environmental issues such as the eutrophication of waters (e.g. rivers and oceans). Increased knowledge and understanding of the negative consequences of nutritional leakage have led to comprehensive mitigation measures, one of which is the construction of wetlands. In order to achieve successful, cost-effective and sustainable measures it is essential to
A Credit Default Swap spread is a reliable measure of credit risk as it is the compensation demanded by a party to bear this risk. Officially, credit risk is denoted as credit ratings announced by credit rating agencies. Since rating announcements contain information regarding credit risk, the market should incorporate this new information into the CDS spread. The aim of this study is to investiga
Background and aim: There is a high interest in determining the absorbed dose in tumors and organs for various radiotherapy cancer treatments. Due to limitations in today's methods of determining the patient specific absorbed dose it is usually not proceeded clinically. The methods are time consuming but also trying for patients, since it depends on several imaging procedures at different time
Introduction: The World Health Organization (WHO) estimates that malaria, the parasitic infection caused by Plasmodium spp., resulted in the deaths of 600,000 people in 2023, predominantly affecting the African region. Background: In an effort to combat the disease, scientists have turned to heavy metal complexes in search of novel antimalarials. With a rise of resistance against existing antipla
The construction of episodic memory is an automatic process. Event segmentation theory proposed that segmentation of the continuous perceptual stream into separate memory events occurs when changes in external boundaries lead to changes in internal perceptual and conceptual boundaries. The influence of perceptual and conceptual boundaries on episodic memory encoding has been the subject of intensi
This paper examines the impact of zombie firms on healthy companies’ growth indicators in the Swedish market. By utilising fixed-effects regression analysis and analysing a comprehensive data set, the paper aims to shed light on the dynamics between zombies’ effects on nonzombies’ development. The findings indicate that zombies have limited effects on healthy companies in Sweden. Contrary to previ
