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Context. The performance of interferometers has been much increased over the past ten years. But the number of observable objects is still limited by the low sensitivity and imaging capability of the current facilities. Studies have been conducted with the aim to propose a new generation of interferometers. Aims. The Carlina concept studied at the Haute-Provence Observatory consists of an optical

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Autochthonous blockfield mantles may indicate alpine surfaces that have not been glacially eroded. These surfaces may therefore serve as markers against which to determine Quaternary erosion volumes in adjacent glacially eroded sectors. To explore these potential utilities, chemical weathering features, erosion rates, and regolith residence durations of mountain blockfields are investigated in the

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Objective To compare drug survival on adalimumab, etanercept and infliximab in patients with rheumatoid arthritis (RA). Methods Patients with RA (n=9139; 76% women; mean age 56 years) starting their first tumour necrosis factor (TNF) inhibitor between 2003 and 2011 were identified in the Swedish Biologics Register (ARTIS). Data were collected through 31 December 2011. Drug survival over up to 5 ye

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Ett av Sveriges sexton miljömål är att bevara den biologiska mångfalden, alltså den mångfald av växt- och djurarter som lever i vårt land. Ett stort hot mot den biologiska mångfalden är fragmentering av de ekosystem där djuren och växterna lever. Vad innebär då fragmentering av ett ekosystem? Enkelt uttryckt kan man se fragmentering som att dela upp ett sammanhängande ekosystem i mindre utspridda The “Eastern slopes of Lake Vättern” is an area situated in the municipality of Jönköping in southern Sweden. The area has a high level of biodiversity of which much is bound to mixed broad-leaved deciduous trees and forests and contains species that are unique for this area in Sweden. The area is a candidate to become a biosphere reserve under the Unesco Man and Biosphere program. One ambition in

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Klimatförändringar har amplifierats sedan den industriella revolutionen och modeller pekar på att förändringen kommer forsätta att öka åtminstone till slutet av detta århundrande. Globala temperaturer och nederbörd förväntas öka avsevärt under detta århundrade. Dessa ökningar förväntas bli särskilt markanta i de arktiska områdena. Torvmyrar belägna på höga latituder vid 0ºC isothermen, såsom StorfThe rate of change of our climate has been amplified since the industrial revolution and is expected to change even further by the end of this century. Global temperature and precipitation are expected to increase considerably over the next century. These increases are expected to be magnified in the Arctic regions. In a high latitude peatland like Storflaket, near Abisko (Northern Sweden), at the

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There is little epidemiological data on heart failure (HF) in the younger age groups dominating clinical HF trials. We assessed gender-specific long-term HF incidence and mortality in an urban community-based sample of middle-aged subjects. Between 1974 and 1992, 33,342 HF-free subjects (10,900 [32.7%] women, mean age 45.7 +/- 7.4 years) were included in the Malmö Preventive Project, on average 21

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Background: Avoidable mortality is considered as a potential indicator of the influences of public health policies and healthcare quality on population health. This study aimed to examine the trend in avoidable mortality and its influence on rising life expectancy (LE) and declining gender gap in LE (GGLE) in Sweden. Methods: We extracted data on causes of death by age, sex, and year from nationa

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With the continued development of tracking technology and increasing interest in animal movement, our understanding of migration behavior has become more comprehensive. However, there are still many species that have not been well studied, particularly sea birds. Here, we present the first year-round Global Positioning System (GPS) tracking data of the Black-tailed Gull (Larus crassirostris) at th

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BACKGROUND: The St Gallen 2019 guidelines for primary therapy of early breast cancer recommend omission of completion axillary lymph node dissection (cALND), regardless of histological type, in patients with one or two sentinel lymph node (SLN) metastases. Concurrently, adjuvant chemotherapy is endorsed for luminal A-like disease with four or more axillary lymph node (ALN) metastases. The aim of t

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Objective: Investigate all-cause and cause-specific late mortality after childhood acute lymphoblastic leukemia (ALL) in a population-based Nordic cohort. Methods: From the cancer registries of Denmark, Finland, and Sweden, we identified 3765 five-year survivors of ALL, diagnosed before age 20 during 1971–2008. For each survivor, up to five matched comparison subjects were randomly selected from t

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IMPORTANCE The extent to which large-caliber axonal degeneration contributes to Alzheimer disease (AD) progression is unknown. Cerebrospinal fluid (CSF) neurofilament light (NFL) concentration is a general marker of damage to large-calibermyelinated axons. OBJECTIVE To test whether CSF NFL concentration is associated with cognitive decline and imaging evidence of neurodegeneration and white matter

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Lake Titicaca is a crucial water resource in the central part of the Andean mountain range, and it is one of the lakes most affected by climate warming. Since surface evaporation explains most of the lake's water losses, reliable estimates are paramount to the prediction of global warming impacts on Lake Titicaca and to the region's water resource planning and adaptation to climate change. Evapora

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Large carnivore conservation in the Swedish multi-use landscapes can only be successful if carnivores can share the landscape with human activities. Interventions to reduce the risk of brown bear, lynx, wolf, and wolverine attacks on domestic animals have become a core element in carnivore management. Whereas the intention is that interventions mitigate human-carnivore interactions, the interventi

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Eight different generations of dolerite dykes crosscutting the Paleoproterozoic basement in West Africa and one in South America were dated using the high precision U–Pb TIMS method on baddeleyite. Some of the individual dykes reach over 300 km in length and they are considered parts of much larger systems of mafic dyke swarms representing the plumbing systems for large igneous provinces (LIPs).

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BACKGROUND: There is a worldwide increase in the incidence of cutaneous malignant melanoma (CMM) among whites. In Sweden, a five-fold increase has been recorded since 1960, although the increase in mortality rate is substantially lower. Tumor thickness is recognized as the most important histologic prognostic factor for primary melanoma. In a previous study, the authors did not find any significan

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This presentation will give an overview of a peer learning model called Supplemental Instruction - Peer Assisted Study Scheme (SI-PASS). SI-PASS was invented at the University of Missouri in Kansas City, USA in the early1970s and was then directed to Universities and for the university students. In this presentation, the focus and discussion will be on how SI-PASS can be implemented in secondary s

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Context. Observational evidence indicates that the orbits of extrasolar planets are more various than the circular and coplanar ones of the solar system. Planet-planet interactions during migration in the protoplanetary disc have been invoked to explain the formation of these eccentric and inclined orbits. However, our companion paper (Paper I) on the planet-disc interactions of highly inclined an

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The use of compressed natural gas (CNG) in light duty applications is still restricted to conventional spark ignition engines operating at low compression ratio, so overall efficiency is limited. A combustion concept that has been successfully applied on large stationary engines and to some extent on heavy-duty engines is dual-fuel combustion, where a compression-ignited diesel pilot injection is

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The oxygen isotopic compositions of calcite grains in four CM carbonaceous chondrites have been determined by NanoSIMS, and results reveal that aqueous solutions evolved in a similar manner between parent body regions with different intensities of aqueous alteration. Two types of calcite were identified in Murchison, Mighei, Cold Bokkeveld and LaPaz Icefield 031166 by differences in their petrogra