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Background: Stroke and acute myocardial infarction (AMI) rank among the leading causes of mortality. Physical activity and exercise are recommended as part of rehabilitation after AMI to prevent cardiovascular events, but the importance for stroke prevention has not been investigated using population-based data. Objectives: To determine associations between participation in exercise-based cardiac
Long-term population studies can identify changes in population dynamics over time. However, to realize meaningful conclusions, these studies rely on accurate measurements of individual traits and population characteristics. Here, we evaluate the accuracy of the observational methods used to measure reproductive traits in individually marked black-tailed godwits (Limosa limosa limosa). By comparin
Context. Tidal interactions between massive galaxies and their satellites are fundamental processes in a universe with a λ cold dark matter (λ CDM) cosmology, and they redistribute material into faint features that preserve records of past galactic interactions. While stellar streams in the Local Group impressively demonstrate satellite disruption, they do not constitute a statistically significan
Objective. To compare the reproducibility of the standing extended view (SEV) (also known as the standing anteroposterior view) with the semiflexed, postero-anterior view [the 'metatarsophalangeal' (MTP)] view for assessing joint space width (JSW) and osteophytes in osteoarthritis of the knee when used in a busy routine X-ray department. Methods. Forty-seven patients (24 men) had both SEV and MTP
Objectives: To examine potential sex differences in cognitive and functional progression rates in Alzheimer’s disease (AD) between patients with different concomitant medications. Methods: The Swedish Alzheimer Treatment Study is a prospective, observational, multicentre study in clinical practice undertaken at the initiation of cholinesterase inhibitor therapy in 1,021 patients diagnosed with mil
Background and aims: Previous studies of primarily Western populations have consistently documented a lower risk of type 2 diabetes (T2D) among people with a higher yogurt intake, but an inconsistent association with milk intake. However, little is known about the association between dairy intake and risk of T2D among Chinese adults who consume considerably less dairy (mainly milk and yogurt) co
This thesis unfolds a journey into the realm of cloud integrated systems. More specifically, it explores the transformational role of diverse cloud infrastructure, be it public or private, centralized or edge-based, when integrated into traditional systems. In this transformation, the cloud assumes the vital role of controllers. Inevitably, this shift towards cloud integration also brings into pla
Background: Effectiveness of biologics has neither been established in patients with high oral corticosteroid exposure (HOCS) nor been compared with effectiveness of continuing with HOCS alone. Objective: To examine the effectiveness of initiating biologics in a large, real-world cohort of adult patients with severe asthma and HOCS. Methods: This was a propensity score–matched, prospective cohort
Background: Proton radiotherapy (RT) is an attractive tool to deliver local therapy with minimal dose to uninvolved tissue, however, not suitable for all patients. The aim was to explore complications, especially severe late complications (grades 3–4), following proton RT delivered to a complete Swedish cohort of paediatric patients aged <18 years treated 2008–2019. Material and Methods: Data was
The Colombian peace agreement, which has brought an end to a prolonged internal armed conflict has led to significant land use changes that underscore existing inequalities and struggles over natural resources. The expansion of industries such as cattle ranching, agriculture, and extraction is encroaching on indigenous territories and protected areas, resulting in negative consequences for communi
Denna studie handlar om att experimentellt karakterisera ett materietillstånd som existerade under de första miljondelarna av en sekund under Big Bang, som vi kallar för Kvark-Gluon-Plasma. Med stora partikelacceleratorer som Large Hadron Collider (LHC) vid CERN, kan vi genom kärnkollisioner med mycket hög energi nå så pass extrema temperaturer och densiteter att vi kan återskapa och studera dettaIn high energy heavy ion collisions, the QCD matter undergoes a phase transition to a hot and dense strongly coupled Quark Gluon Plasma, where quarks and gluons are deconfined in a volume of nuclear dimensions. At intermediate pT, 2 < p T < 8 GeV/c, a decoupling from pure hydrodynamical flow is observed, most noticeable in central collisions, demonstrated by the peak in the ratio of baryons to mes
BACKGROUND: Patients undergoing hepato-pancreato-biliary surgery are typically preoperatively assessed using the American Society of Anesthesiologists (ASA) classification, which is also used for case-mix adjustment when comparing centre outcomes. Studies determining the inter-rater variability of the ASA classification within hepato-pancreato-biliary surgery are currently lacking.METHODS: An inte
Negative symptoms in schizophrenia spectrum are associated with minimal treatment responses. The search for effective treatments is potentially hampered by heterogenous study-designs and sample characteristics depending on the intervention category. This PRISMA-compliant systematic review/synthesis aims to describe the literature on negative symptoms interventions for schizophrenia spectrum disord
This thesis delves into the complex architecture of dynamic sensory information processing in the neocortex. Specifically, it asks how primary sensory cortical regions are influenced by local and widespread cortical state changes. Central to this question is the exploration of two historically opposing information processing frameworks emphasizing a local and global information processing principl
Popular summary The fate of non-steroidal anti-inflammatory drugs The knowledge about distribution of drugs between sewage sludge, water phases and water living organisms is vital for predictions of the fate and transport routes of toxic substances to the environment. And the distribution of drugs in the environment can be used as a base for risk assessments and it also can be used to define desir
The present study investigated second language (L2) learners’ processing of filler-gap dependencies and tested the implications of Clahsen and Felser’s (2006) shallow structure hypothesis according to which L2 learners underuse syntactic information during the processing of these sentence types. Advanced L2 learners of English (native Swedish speakers) listened to English sentences with object-rel
Drawing on practice centered approaches to consumption, this study situates a cultural analysis of Instagram, a smartphone-‐based image sharing application used by over 80 million people worldwide, within wider discourses on reflexive modernity, critical media studies, prosumption, and late-‐modern consumer culture. A seven-‐day diary study with 25 international participants, supplemented by pa
This thesis develops and evaluates a Random Forest (RF) machine learning classification framework for detecting clear-cut forest felling events using Sentinel-2 multispectral satellite data. While RF classification is widely applied in forest monitoring, its performance for operational clear-cut detection in Latvian semi-boreal forests remains insufficiently studied. This study aims to assess the
Patterns of local adaptation are expected to emerge when selection is spatially heterogeneous and sufficiently strong relative to the action of other evolutionary forces. The observation of local adaptation thus provides important insight into evolutionary processes and the adaptive divergence between populations. The seaweed fly Coelopa frigida exhibits an inversion polymorphism in all population
Genetic risk factors play important roles in the etiology of oral, dental, and craniofacial diseases. Identifying the relevant risk loci and understanding their molecular biology could highlight new prevention and management avenues. Our current understanding of oral health genomics suggests that dental caries and periodontitis are polygenic diseases, and very large sample sizes and informative ph
