Filtyp
Background: Alzheimer’s disease is a progressive, irreversible, and fatal disease for which accumulation of amyloid beta is thought to play a key role in pathogenesis. Aducanumab is a human monoclonal antibody directed against aggregated soluble and insoluble forms of amyloid beta. Objectives: We evaluated the efficacy and safety of aducanumab in early Alzheimer’s disease. Design: EMERGE and ENGAG
Unstructured citizen-science data are increasingly used for analysing the abundance and distribution of species. Here we test the usefulness of such data to predict the seasonal distribution of migratory songbirds, and to analyse patterns of migratory connectivity. We used bird occurrence data from eBird, one of the largest global citizen science databases, to predict the year-round distribution o
This study evaluated the suitability of the latest retrospective Integrated Multi-satellitE Retrievals for Global Precipitation Measurement V06 (IMERG) Final Run product with a relatively long period (beginning from June 2000) for drought monitoring over mainland China. First, the accuracy of IMERG was evaluated by using observed precipitation data from 807 meteorological stations at multiple temp
Sunlight is a plentiful, continuously flowing source of energy, fuelling life on Earth as we know it. To use this potential, plants, cyanobacteria and photosynthetic bacteria evolved to absorb solar radiance and convert it into a chemically stable form by performing a process known as photosynthesis. Despite a wide variety of photosynthetic systems, the initial steps of photosynthesis are similar.
Induced polarization (IP) is a common method in ore exploration. IP spectra measured over a wide frequency range can be used to characterize material properties of ores, slags and other residual material from mines and processing facilities. Previous studies have shown that IP parameters are sensitive to type, content or grain size of electronically conductive or semi-conductive minerals. Up to no
“The Covid 19 pandemic took the meetings industry from top to bottom in one move”. These were the introducing words from the CEO of a large Swedish network of meetings firms, in their annual report for 2020. In the beginning of that year, one of the most challenging crises in the history of the meetings organizations emerged. Now, two years on the pandemic has changed the conditions for the entire
Introduction: The Bogong moth Agrotis infusa is well known for its remarkable annual round-trip migration from its breeding grounds across eastern and southern Australia to its aestivation sites in the Australian Alps, to which it provides an important annual influx of nutrients. Over recent years, we have benefited from a growing understanding of the navigational abilities of the Bogong moth. Mea
BACKGROUND: Lactiplantibacillus plantarum HEAL9 and Lacticaseibacillus paracasei 8700:2 positively affect the fecal bacteriome in children with celiac disease autoimmunity after 6 months of supplementation. The aim of the present investigation was to study the effects of Lactiplantibacillus plantarum HEAL9 and Lacticaseibacillus paracasei 8700:2 on the single-cell parasitome, with a primary focus
Background: Understanding the relationship among changes in Clinical Dementia Rating (CDR), patient outcomes, and probability of progression is crucial for evaluating the long-term benefits of disease-modifying treatments. We examined associations among changes in Alzheimer’s disease (AD) stages and outcomes that are important to patients and their care partners including activities of daily livin
Adolescence is a period of significant physiological changes, and likely a sensitive window to chemical exposure. Few nation-wide population-based studies of chemical body burdens in adolescents have been published. In the national dietary survey Riksmaten Adolescents (RMA) 2016–17, over 13 chemical substance groups, including elements, chlorinated/brominated/fluorinated persistent organic polluta
Classroom interaction engendered by different form-and-accuracy exercises with advanced students This presentation focuses on the impact of two different kinds of form-and-accuracy grammar exercises on teacher-student classroom interaction with advanced Swedish-speaking L2 users of English. The purpose is to explore whether the exercises lead to a) the same amount and type of interaction, and b)
OBJECTIVE: An experienced sonographer can by listening to the Doppler audio signals perceive various timbres that distinguish different types of umbilical artery flow despite an unchanged pulsatility index (PI). Our aim was to develop an objective measure of the Doppler audio signals recorded from fetoplacental circulation in a sheep model.METHODS: Various degrees of pathological flow velocity wav
The aim of this thesis was to elucidate developments in epidemiology, clinical manifestations and complications in Chlamydia trachomatis (C.trachomatis) and Mycoplasma genitalium (M.genitalium) infection. In study I the frequencies of non-gonococcal salpingitis, gonococcal salpingitis and ectopic pregnancy (EP) were observed over a period of 28 years and correlated to the prevalence of Neisseria g
ABSTRACT Background Prevalence rates of syphilis vary extensively between the different countries in Africa but are in general high. Recent research indicates a declining prevalence trend of syphilis infection in the general population in West Africa. As syphilis is a cause of reproductive morbidity, poor pregnancy outcome and may be an important contributor to the HIV epidemic, trends in syphilis
Denna uppsats behandlar medling vid brott, samt åtalsunderlåtelseinstitutet avseende unga lagöverträdare, som regleras i 17§ i lagen (1964:167) med särskilda bestämmelser om unga lagöverträdare (LUL). Mitt huvudsakliga syfte är att genom en kvalitativ undersökning försöka utröna i hur stor omfattning och på vilket sätt som medlingsinstitutet påverkar åklagarnas val att meddela åtalsunderlåtelse inThis essay addresses victim-offender mediation and the institution of abstention from prosecution with regard to young offenders. Focus will be on Section 17 of the Young Offenders (Special Provisions) Act (LUL - 1964:167), as my primary aim is to ascertain, by means of a qualitative investigation, to what extent and in what ways the Swedish National Mediation Office influences a prosecutor's
INTRODUCTION: This study explores transient and stationary effects of sympathetic and parasympathetic stimulation on f-wave characteristics in atrial fibrillation (AF) patients undergoing a tilt test. Transient phase is defined as the initial 2-minute interval following each postural change, reflecting immediate autonomic adaptation, whereas steady phase refers to the subsequent interval (from 3 m
The possible implication of the gasotransmitters NO and CO for the development of diabetes remains unresolved. Our previous investigations in rodents suggested NO being inhibitory, and CO stimulatory, to glucose-stimulated insulin secretion (GSIS). Here we studied the possible role of these gasotransmitters in both murine and human type 2 diabetes (T2D) by mapping the expression pattern of neural
BACKGROUND: Glibenclamide (Gb) may provoke long-lasting hypoglycaemic reactions, and one of the known risk factors is impaired renal function. We have demonstrated Gb to have a terminal elimination half-life of 15 h, and the main metabolites have a hypoglycaemic effect. With few exceptions, detailed studies on second generation sulphonylureas in diabetics with impaired renal function are lacking.
Background Systemic Lupus Erythematosus (SLE) affects mostly women in childbearing age. Modern management of SLE patients has improved the pregnancy outcomes over the last decades. However, there is still an increased risk of maternal, fetal and neonatal complications. In this longitudinal follow-up of pregnant women affected by SLE, we aimed to investigate which clinical and immunological feature
Satellite remote sensing of plant phenology provides an important indicator of climate change. However, start of the growing season (SOS) estimates in Northern Hemisphere boreal forest areas are known to be challenged by the presence of seasonal snow cover and limited seasonality in the greenness signal for evergreen needleleaf forests, which can both bias and impede trend estimates of SOS. The ne
