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Isolated Ca2+-binding EF-hand peptides have a tendency to dimerize. This study is an attempt to account for the coupled equilibria of Ca2+-binding and peptide association for two EF-hands with strikingly different loop sequence and net charge. We have studied each of the two separate EF-hand fragments from calbindin D-9k. A series of Ca2+-titrations at different peptide concentrations were monitor
Popular Abstract in Swedish TARMENS UPPTAG AV GALAKTOLIPIDER Världens vanligaste fettmolekyler Inuti cellerna hos alla växter finns en komponent som kallas kloroplast. I kloroplasten sker den livsviktiga fotosyntesen där energi från solljuset omvandlar koldioxid och vatten till socker och syre. Inuti kloroplasten finns en stor mängd membraner som kan liknas vid en bunt platta säckar. Genom dessa Galactolipids: digalactosyldiglyceride (DGalDG), monogalactosyldiglyceride (MGalDG) and sulfoquinovosyldiglyceride (SQDG) are the major lipid components in thylakoid membranes of chloroplasts i.e. the site of photosynthesis in plants. They are the most abundant membrane lipids in nature, and thus important sources of essential fatty acids for herbivores and omnivores. This thesis investigates the
The cryptomonads is a well-defined lineage of unicellular eukaryotes, composed of several marine and freshwater groups. However, the evolutionary relationships among these groups are unclear due to conflicting inferences between morphological and molecular phylogenies. Here, we have inferred the evolutionary relationships among marine and freshwater species in order to better understand the import
Humans utilise about 40% of the earth's net primary production (NPP) but the products of this NPP are often managed by different sectors, with timber and forest products managed by the forestry sector and food and fibre products from croplands and grasslands managed by the agricultural sector. Other significant anthropogenic impacts on the global carbon cycle include human utilization of fossil fu
Conclusions. The results confirm that tumour stage influences the risk of recurrence/second primary tumour (SPT). High-risk human papillomavirus (HPV)-infected patients have a significantly higher risk of recurrence/SPT compared with high-risk HPV-negative patients. High alcohol consumption was associated with a higher risk of recurrence/SPT. In this study, the competing risk of death in intercurr
Most existing traffic conflict indicators do not sufficiently take into account the severity of the injuries resulting from a collision had it occurred. Thus far, most of the indicators that have been developed express the severity of a traffic encounter as their proximity to a collision in terms of time or space.This paper presents the theoretical framework and the first implementation of Extende
In the 2011 census of India, more than 2500 settlements have been newly inducted into the category of ‘census towns’ – the lowest size-class of urban settlements in India. This is a staggering figure in light of the observation that a comparable number constituted the total number of all urban settlements recorded since 1900. Furthermore, it has been revealed through aerial images, that a vast maj
BACKGROUND AND OBJECTIVE: Venous thrombosis is a common disease annually affecting 1 in 1000 individuals. The multifactorial nature of the disease is illustrated by the frequent identification of one or more predisposing genetic and/or environmental risk factors in thrombosis patients. Most of the genetic defects known today affect the function of the natural anticoagulant pathways and in particul
In this paper, the investment in new desalination capacity, expressed as daily production capacity, was studied as a function of oil production and population increase for a large group of countries for the last 25 years. These countries were selected for their large desalination production and Sweden presented as reference. Oil production correlated well with investments in new desalination capac
Among DQ6 molecules, DQA1(*)0102-DQB1(*)0602 is negatively associated with insulin-dependent diabetes mellitus (IDDM), but DQA1(*)0102-DQB1(*)0604 shows a neutral to positive association in Swedish children with IDDM. The aim of this study was to identify critical DQB1 residues that may account for the differences in IDDM association observed for these two DQ6 molecules. HLA-DQ genotyping in 425 I
Neuropeptide Y (NPY) is a well-established vasopressor agent present in sympathetic perivascular nerves. Recently, it was found that high doses of the peptide cause a biphasic pressor-depressor response upon intravenous administration. We now report that C-terminal NPY fragments (NPY-(18-36) and NPY-(22-36] given intravenously to conscious or pithed (areflexive) male Sprague-Dawley rats mimic the
Introduction: Lower limb revascularization with inguinal incisions is a common vascular surgical procedure. Due to risk of injury to lymphatic vessels and a diverse bacterial flora in the groin, surgical site infections (SSI) represent a common and sometimes life-threatening complication. While transverse incisions in endovascular aneurysm repair has a low SSI rate, vertical incisions in thrombend
Cucurbit crops have steadily increased in production over the last 50 years, particularly in Asia where pioneering technological advancements and genetic improvements have created new hybrid varieties. Generally, cucurbits are dependent on insect-pollination for fruit set and are popular species for pollination studies. This review systematically summarises pollination research conducted in the ma
The increasing awareness of the urban environment’s contribution to climate change and other environmental problems has brought about a myriad of commercially available schemes that aim to mitigate detrimental impacts on the environment. These schemes, or rating tools, provide a convenient way to benchmark the eco-efficiency of buildings and, more recently, neighbourhood developments. Furthermore,
This study encompasses the development of a long-term coastal evolution model with enhanced capabilities to simulate simultaneously the cross-shore and longshore evolution of the coast. The paper starts by reviewing the theory related to cross-shore and longshore sediment transport, which are the major components integrated in the model. Major advances were made by introducing modules to better ac
An aqueous system containing fluorapatite (Ca-5(PO4)(3)F), (FAP) and varying amounts of goethite (alpha-FeOOH) has been investigated. Batch experiments and attenuated total reflectance Fourier transform infrared (ATR-FTIR) spectroscopy were used to monitor the dissolution products of FAP, as well as the adsorption, and phase transformation of phosphate at the goethite surface over a period of 129
Purpose: An unprecedented scale of human migration has lead humanitarians to view camps as long-term settlements rather than temporary holding facilities. The purpose of this paper is to increase the understanding of and identify challenges with this proposed new approach to camp design. Design/methodology/approach: Based on the camp design literature, the authors developed an interview guide and
Human cystatin C (hCC) is a cysteine proteinase inhibitor involved in pathophysiological processes of dimerization and amyloid formation. These processes are directly associated with a number of neurodegenerative disorders such as Alzheimer disease or hereditary cystatin C amyloid angiopathy (HCCAA). One of the ideas on how to prevent amyloid formation is to use immunotherapy. HCC3 is one of a gro
