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Molecular studies of pancreatic cancer: Characterization of the transforming growth factor beta signaling pathway

Popular Abstract in Swedish Pankreascancer (cancer i bukspottkörteln) drabbar ungefär 900 personer om året i Sverige. Tumörformen har tidigare varit vanligare hos män men är numera lika vanlig hos män och kvinnor. Pankreascancer är ovanligt före 40 års ålder, men ökar stadigt med åldern och ungefär 80% av dem som drabbas är över 60 år gamla. Pankreascancer är en aggressiv tumörform och på grund avIn the present thesis, genetic abnormalities in pancreatic cancer were studied, with special emphasis on alterations of components involved in the transforming growth factor beta (TGFB) signaling pathway. In the first study, fluorescence in situ hybridization and cytogenetic analyses revealed aberrations of chromosome 18 in all 13 pancreatic carcinoma cell lines studied, in particular frequent bre

SI-PASS leader development activities

Network with fellow SI-PASS leaders across Europe. The SI-PASS leader development activities focus on continuing professional development for SI-PASS student leaders. These sessions offer a chance to network with SI-PASS leaders from across Europe and are a way to exchange ideas, experiences, best practice and challenges in a relaxed setting. The sessions are hosted by the European Centre for SI-P

https://www.si-pass.lu.se/student-si-pass-leader/si-pass-leader-development-activities - 2026-05-29

Invitation eeeaw

The European Entrepreneurship Education Award + Workshop 2013 Lund, May 16–17 2013 Advancing Entrepreneurship Education For the second year running, Sten K. Johnson Centre for Entrepreneurship at Lund University cordially invites you to the European Entrepreneurship Education Award + Workshop 2013. The award that recognizes pioneers in entrepreneurship education and a workshop that allows you to i

https://www.lu.se/sites/www.lu.se/files/invitation_eeeaw.pdf - 2026-05-30

Human studies evaluating dGEMRIC as a prognostic tool for knee osteoarthritis

Popular Abstract in Swedish Artros är den vanligaste ledsjukdomen i världen, och orsakar ledvärk och stelhet. Artros leder till försvagning av brosket och sedermera förlust av allt större mängder belastat ledbrosk. För närvarande är vanlig röntgen den gyllene standarden för att diagnostisera knäartros. Dock är sjukdomsförloppet ofta väldigt långt framskridet när broskförändringar börjar synas på rOsteoarthritis (OA) is the most common joint disorder worldwide, causing joint pain and stiffness. The current gold standard for diagnosing knee OA is radiography. However, the disease has often progressed well beyond the point of no return once radiographic cartilage changes become visible. Identifying changes in cartilage at an early stage of OA would allow curative or prophylactic treatment to

Återtagandeförbehåll – En effektiv säkerhet?

I svensk rätt finns det vissa möjligheter för säljare att i avtalet med en köpare förbehålla sig rätten att återta egendomen om betalning inte fullgörs, ett s.k. återtagandeförbehåll. Uppsatsen har som syfte att utreda de krav som ställs för ett sakrättsligt giltigt återtagandeförbehåll, enligt den svenska rättsordningen. Nuvarande reglering gör det inte möjligt för en säljare att genom återtagandFor a creditor in commercial transactions, a promise to pay is seldom sufficient. For that reason the creditor would like to secure his claim to minimise the risks arising from the contract under the credit terms. One way of securing his claim is by using retention of title clause. The thesis aims to investigate the requirements for an indefeasible protected retention of title clause, according to

Mindfulness då och nu, en analys av mindfulness som begrepp och dess användning i en arbetslivskontext - en litteraturstudie

Denna kandidatuppsats är en litteraturstudie som beskriver och analyserar definitionen samt användningen av mindfulness. Rapporter från Försäkringskassan och SBU visar på en skrämmande ökning av sjukfall relaterade till stress och psykisk ohälsa, vilket har lett till stor problematik för företag och organisationer ekonomiskt såväl som vid rekrytering och bemanning. Mindfulness är ett begrepp som p

Blocking the swell: Beta blockers' association with brain edema for glioblastoma patients

Glioblastom är en mycket aggressiv hjärntumör som trots över 100 år utav forskning i snitt dödar patienter åtta månader efter diagnos. I denna studie undersöks alternativa behandlingsmetoder för den svullnad som drabbar patienten när tumören växer och opereras. Om man lyckas hitta ett alternativ till kortison, som idag används, finns det stor potential i att behandla glioblastompatienter med virusGlioblastoma is a highly aggressive brain tumor that kills roughly 9,000 Americans yearly. Although a known disease for over a century, little progress has been made in treatment development. A breakthrough may be on its way as recent research suggests glioblastoma patients can be treated with virus injections, oncolytic virotherapy in medical terms. However, this treatment method is somewhat inhi

Sverige blir äldre - Är bostadsutbudet anpassat för en åldrande befolkning?

Sverige genomgår för tillfället strukturella förändringar i befolkningssammansättningen. Andelen äldre blir större och andelen yngre blir tvärtemot mindre. Denna demografiska utveckling får stora följder för samhället, inte minst för bostadsmarknaden. Människor i olika åldrar har olika boendepreferenser och när fördelningen i samhället förändras, förändras också behovet av olika typer av bostäder.Sweden is facing significant demographic changes, with declining birth rates and an ageing population that is not only growing older but also growing in number. These shifts affect many areas of society, particularly the housing market. Since people of different ages have different housing preferences, the demand for various types of housing is also changing. Against this background, this study ex

Integrated Optics Set-up for Photodynamic Therapy

Interstitial photodynamic therapy is a local solid cancer treatment technique that relies on the simultaneous presence of light, photosensitizer and oxygen. SpectraCure AB has been developing a light delivery system for prostate cancer therapy. The use of this instrument is meant to be extended to other solid tumor treatments such as cancer in the pancreas or the ear, nose and throat tract. The co

Åtgärdsuppföljning inom vattenförvaltning - Praktisk implementering av lokalt förvaltningsarbete vid Vombsjön

Du kanske aldrig har funderat på vattnet som kommer ut ur kranen? Till diskmaskinen, matlagningen, duschen eller vattenspridaren? Rent dricksvatten är något vi tar för givet, men trots det har sjön som förser stora delar av sydvästra Skåne med dricksvatten omfattande miljöproblem. Vombsjön är belägen mitt i Skånes jordbrukslandskap där näringsämnen läcker från åkermarker och små avlopp. SjönsClean drinking water is often taken for granted. However, the lake that supplies the greater part of southwestern Scania with drinking water has severe environmental problems regarding the chemical and ecological status. The organization Fokus Vombsjön has now taken it upon themselves to develop a water management plan for the lake, with the goal to improve its overall status. The aim of this s

Brottslighet i skymundan - En undersökning av kvinnors våld mot män och domstolens bedömning därav i ett genusrättsvetenskapligt perspektiv

Straffrättens lagtext är könsneutral, men inte utan undantag. Ett undantag är grov kvinnofridskränkning som tillsammans med grov fridskränkning stadgas i BrB 4 kap. 4a §. Skillnaden mellan fridskränkningsbrotten är att grov kvinnofridskränkning har ett förbestämt könskrav på gärningspersonen och brottsoffret samt ställer krav på deras relation. Gärningspersonen, en man, och brottsoffret, en kvinnaCriminal law is gender neutral in its written construction, but there are exceptions. One of those exceptions is gross violation of women’s integrity. Its sibling provision is called gross violation of integrity, which is gender neutral. The difference between the two provisions is that the relation of the perpetrator and the victim in gross violation of women’s integrity is predetermined in terms

När en anställd uppvisar påverkat beteende eller liknande

Rutin för chefer med ansvar för anställdas arbetsmiljö På denna sida kan du läsa mer om vad du som chef ska göra när en anställd uppvisar påverkat beteende eller liknande i arbetet. Innehåll på sidan:ChecklistaBedömning av om anställd är i skick att utföra sitt arbeteKontroll av nykterhetSkicka hem din anställda på ett säkert sättMedvetandegörande samtalOm din anställda säger nej till provtagning

https://www.hr-webben.lu.se/arbetsmiljo/anstalldas-halsa/riskbruk-och-skadligt-bruk/rutin-chefer-med-ansvar-anstalldas-arbetsmiljo/nar-en-anstalld-uppvisar-paverkat-beteende-eller-liknande - 2026-05-29

Valorisation of fish waste biomass through recovery of nutritional lipids and biogas

Popular Abstract in English Commercial fish catch in Eastern Africa is dominated by Nile Perch. Of the fish that is processed for human consumption, 30-40 % is wasted. Currently, these wastes are not fully utilized; they are sold off at low price, converted to low valued products or left to decompose leading to environmental pollution and wastage of bioresource. This biomass has however a potentiaCommercial fish catch in Eastern Africa is dominated by Nile Perch. Of the fish that is processed for human consumption, 30-40% is wasted. Currently, these wastes are not fully utilized; they are sold off at low price, converted to low valued products or left to decompose leading to environmental pollution and wastage of bioresource. This biomass has however a potential to generate considerable re

Quantifying archaeo-organic degradation – A multiproxy approach to understand the accelerated deterioration of the ancient organic cultural heritage at the Swedish Mesolithic site Ageröd

Despite a growing body of evidence concerning accelerated organic degradation at archaeological sites, there have been few follow-up investigations to examine the status of the remaining archaeological materials in the ground. To address the question of archaeo-organic preservation, we revisited the Swedish, Mesolithic key-site Ageröd and could show that the bone material had been subjected to an

Previous winners of CFE's Best Thesis Award

The Center for European Studies has awarded prizes and honorable mentions to essays in the fields of social sciences, humanities, law, and economics with connections to Europe and the EU for over 20 years. Below you can read about the recipients of the prize throughout the years. 2025Best Thesis: Naod Habtemichael, "A Tale of Two Countries: Analysing Swedish and Danish Diplomatic Actions within th

https://www.cfe.lu.se/en/activities/best-thesis-award/previous-winners-cfes-best-thesis-award - 2026-05-29

Process-based models not always better than empirical models for predicting budburst of Norway spruce and birch in Europe.

Budburst models have mainly been developed to capture the processes of individual trees, and vary in their complexity and plant physiological realism. We evaluated how well eleven models capture the variation in budburst of birch and Norway spruce in Germany, Austria, the United Kingdom and Finland. The comparison was based on the models performance in relation to their underlying physiological as

Defining biochemical recurrence of prostate cancer after radical prostatectomy: a proposal for a standardized definition

PURPOSE: Prostate-specific antigen (PSA) defined biochemical recurrence (BCR) of prostate cancer is widely used for reporting the outcome of radical prostatectomy (RP). A standardized BCR definition is lacking, and overall progression-free probability and risk of subsequent metastatic disease progression may vary greatly depending on the PSA criterion used. Ten definitions of BCR were evaluated to

Comparison of Grand Canonical and Conventional Molecular Dynamics Simulation Methods for Protein-Bound Water Networks

Water molecules play important roles in all biochemical processes. Therefore, it is of key importance to obtain information of the structure, dynamics, and thermodynamics of water molecules around proteins. Numerous computational methods have been suggested with this aim. In this study, we compare the performance of conventional and grand-canonical Monte Carlo (GCMC) molecular dynamics (MD) simula

Unusual CO adsorption sites on vanadium oxide-Pd(111) "inverse model catalyst" surfaces

The morphology, structure, and reactivity of vanadium oxide-decorated Pd(111) surfaces, which have been subjected to oxidation and reduction treatments, have been investigated by scanning tunneling microscopy (STM), high-resolution electron energy loss spectroscopy (HREELS), and high-resolution X-ray photoelectron spectroscopy (HR-XPS) with synchrotron radiation combined with ab initio density fun

Quality of life in patients with recurrent ovarian cancer treated with niraparib versus placebo (ENGOT-OV16/NOVA) : results from a double-blind, phase 3, randomised controlled trial

Background: Quality of life (QOL) has become an important complementary endpoint in cancer clinical studies alongside more traditional assessments (eg, tumour response, progression-free survival, overall survival). Niraparib maintenance treatment has been shown to significantly improve progression-free survival in patients with recurrent ovarian cancer. We aimed to assess whether the benefits of e