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Extremely large differences in DFT energies for nitrogenase models

Nitrogenase is the only enzyme that can cleave the triple bond in N2, making nitrogen avaiable for other organisms. It contains a complicated MoFe7S9C(homocitrate) cluster in its active site. Many computational studies with density-functional theory (DFT) of the nitrogenase enzyme have been presented, but they do not show any consensus-they do not even agree where the first four protons should be

Incidence and survival of epithelial ovarian, fallopian tube, peritoneal, and undesignated abdominal/pelvic cancers in Sweden 1960–2014 : A population-based cohort study

Background: Despite improved surgical and oncological treatment, ovarian cancer continues to be the most lethal of the gynecologic malignancies. We aimed to analyze survival trends in epithelial ovarian cancer with regard to age, tumor site, and morphology in Sweden 1960 to 2014. Methods: A nationwide population-based study was conducted using data from the Swedish Cancer Registry on 46,350 women

CS MSc Thesis Presentation 5 June 2026

5 June 2026 10:15 to 11:00 | One Computer Science MSc thesis to be presented on 5 June Friday, 5 June there will be a master thesis presentation in Computer Science at Lund University, Faculty of Engineering.The presentation will take place in E:2116.Note to potential opponents: Register as an opponent to the presentation of your choice by sending an email to the examiner for that presentation (fi

https://www.cs.lth.se/en/calendar/cs-msc-thesis-presentation-5-june-2026 - 2026-05-29

Free radicals and brain damage

Although free radicals have been suggested to contribute to ischemic brain damage for more than 10 years, it is not until quite recently that convincing evidence has been presented for their involvement in both sustained and transient ischemia. The hypothesis is examined against current knowledge of free radical chemistry, as it applies to biological systems, and of cellular iron metabolism. It is

Enzymatic synthesis of N-alkanoyl-N-methylglucamide surfactants: solvent-free production and environmental assessment

A biocatalysis based method for the solvent-free production of N-alkanoyl-N-methylglucamide (MEGA) surfactants was developed and used as a case study for the evaluation of different environmental assessment tools, such as the freeware package EATOS (Environmental Assessment Tool for Organic Synthesis). In order to also consider energy usage and process facilities, e. g. heating, stirring and vacuu

Catalytic Cycle of Multicopper Oxidases Studied by Combined Quantum- and Molecular-Mechanical Free-Energy Perturbation Methods.

We have used combined quantum mechanical and molecular mechanical free-energy perturbation methods in combination with explicit solvent simulations to study the reaction mechanism of the multicopper oxidases, in particular, the regeneration of the reduced state from the native intermediate. For 52 putative states of the trinuclear copper cluster, differing in the oxidation states of the copper ion

Engineering of Human Fetal Hemoglobin

In blood, the oxygen-transporting protein hemoglobin (Hb) governs the oxygenation of cells and tissues. Naturally, this protein has claimed a place in the center of the research field of artificial oxygen therapeutics. Such Hb-based products have used cell-free Hb purified from human, bovine, invertebrate, or recombinant sources to create hemoglobin-based oxygen carriers (HBOCs). However, administ

Habitat associations of the Coastal Giant Salamander (Dicamptodon Tenebrosus) at its northern range limit

Knowledge of species-environment associations is critical for the management of threatened amphibian populations facing habitat fragmentation and a restricted range. The Coastal Giant Salamander (Dicamptodon tenebrosus) is subject to habitat degradation from logging and human development and is classified as Threatened at its northern range limit in British Columbia, Canada. We examined habitat as

Guanine-nucleotide exchange on ribosome-bound elongation factor G initiates the translocation of tRNAs

Background. During the translation of mRNA into polypeptide, elongation factor G (EF-G) catalyzes the translocation of peptidyl-tRNA from the A site to the P site of the ribosome. According to the 'classical' model, EF-G in the GTP-bound form promotes translocation, while hydrolysis of the bound GTP promotes dissociation of the factor from the post-translocation ribosome. According to a more recen

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Dinka and the architecture of long-distance extraction∗ Coppe van Urk (cvanurk@mit.edu) Norvin Richards (norvin@mit.edu) Massachusetts Institute of Technology GLOW 36, Lund University In the Nilotic language Dinka Nyarweng, both C and v have the EPP property: one XP must sit in their specifier (1) and (2): (1) CP XP C’ C TP . . . (2) vP XP v’ v VP . . . In this talk, we show that this system provi

https://konferens.ht.lu.se/fileadmin/user_upload/sol/ovrigt/konferens_glow36/Handouts_and_Presentations/van_Urk_and_Richards.pdf - 2026-05-30

Möt människorna bakom forskningen – Vetenskap och Hälsa

Möt människorna bakom forskningen – Vetenskap och Hälsa Vetenskap och hälsa Populärvetenskapligt om medicinsk forskning i Skåne Teman Podd Tidskrift Prenumerera Om webbplatsen Kontakt Sök Sök Visa övriga teman: Beroende Tillfreds med livet Stroke Klimakteriet Avancerat och skräddarsytt för dig Ungdomars hälsa Barn med ätsvårigheter Avancerad vård – inte bara på sjukhus Fertilitet Kvinnors hälsa Så

https://www.vetenskaphalsa.se/temasida/mot-manniskorna-bakom-forskningen/ - 2026-05-30

”Men i mitt hemland blir jag kallad för svensk … Sån ironi …” - en kvalitativ studie om hur kosovoalbaner förhåller sig till sin identitet

Inom identitetsforskning finns det olika definitioner av identitet. För att få en djupare förståelse för begreppet identitet, har jag valt att undersöka hur kosovoalbaner förhåller sig till sin identitet i ett svenskt samhälle. De empiriska uppgifterna samlades in genom kvalitativa semi-strukturerade intervjuer. Min analys baserades på begreppen identitet, tillhörighet och kultur. Baserat på det e

En MIFO fas 1-inventering av fyra potentiellt förorenade områden i Jönköpings län

Arbetet med att identifiera och inventera förorenade områden är en del av Sveriges miljökvalitetsmål. Regeringen har fastställt 16 mål, och ett av dessa är Giftfri miljö. För att våra kommande generationer ska få leva i en miljö fri från föroreningar behöver vi städa upp efter nuvarande och tidigare farliga utsläpp. Landets länsstyrelser har fått i uppdrag av Regeringen att genomföra identifieringThe process of identifying and inventorying polluted areas is part of The Environmental Objectives in Sweden. The government has put down 16 objectives, and one of these is A Non-Toxic Environment. To ensure that our future generations will live in an environment free from pollution, we need to clean up after current and former hazardous emissions. All of Sweden’s Länsstyrelser have been commissio

Transferability of Online Store Image- A Comparative Study of Zalando's Online Store Image In Germany, Sweden and The Netherlands.pdf

Purpose: The purpose of this thesis is to examine the role of online store image in the internationalization process of online retailers. Based on the assumption that a favorable image is a competitive advantage for retailers, this master thesis examines whether or not a favorable domestic online store image, can be replicated in the in- ternationalization process of online retailers. Using a comp

Kroppens egen medicin skyddar mot infektion – Vetenskap och Hälsa

Kroppens egen medicin skyddar mot infektion – Vetenskap och Hälsa Vetenskap och hälsa Populärvetenskapligt om medicinsk forskning i Skåne Teman Podd Tidskrift Prenumerera Om webbplatsen Kontakt Sök Sök Kroppens egen medicin skyddar mot infektion 2010-06-04 ⚠️ Den här artikeln är mer än 5 år gammal. Nya forskningsrön kan ha tillkommit. Artur Schmidtchen leder ett internationellt forskarlag. Foto: R

https://www.vetenskaphalsa.se/kroppens-egen-medicin-skyddar-mot-infektion/ - 2026-05-30

Opportunities and challenges using short-pulse X-ray sources.

Free-electron lasers will change the way we carry out time-resolved X-ray experiments. At present date, we use laser-produced plasma sources or synchrotron radiation. Laser-produced plasma sources have short pulses, but unfortunately large pulse-to-pulse fluctuations and large divergence. Synchrotron radiation from third generation source provide collimated and stable beams, but unfortunately long

Identification of the probable inhibitory reactive sites of the cysteine proteinase inhibitors human cystatin C and chicken cystatin

When an excess of human cystatin C or chicken cystatin was mixed with papain, an enzyme-inhibitor complex was formed immediately. The residual free cystatin was then progressively converted to a form with different electrophoretic mobility and chromatographic properties. The modified cystatins were isolated and sequenced, showing that there had been cleavage of a single peptide bond in each molecu