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Resistance to activated protein C (APC) is the most prevalent inherited cause of venous thrombosis. The APC resistance phenotype is associated with a single point mutation in the factor V gene, changing Arg506 in the APC cleavage site to a Gln. We have investigated 50 Swedish families with inherited APC resistance for this mutation and found it to be present in 47 of them. Perfect cosegregation be
Translocation of the tRNA·mRNA complex through the bacterial ribosome is driven by the multidomain guanosine triphosphatase elongation factor G (EF-G). We have used isothermal titration calorimetry to characterize the binding of GDP and GTP to free EF-G at 4°C, 20°C, and 37°C. The binding affinity of EF-G is higher to GDP than to GTP at 4°C, but lower at 37°C. The binding enthalpy and entropy chan
BACKGROUND: Hair cosmetics such as hair dyes, bleaching, waving, and cleansing products are composed of numerous chemical ingredients. Allergic reactions to these contact allergens, other than p-phenylenediamine, are rarely reported.OBJECTIVES: To study the incidence of patch test reactions to hair cosmetic allergens and identify the factors associated with hair cosmetic allergy in Thailand.METHOD
Bio-based 5-hydroxymethylfurfural (HMF) serves as an important platform for several chemicals, among which 2,5-furan dicarboxylic acid (FDCA) has attracted considerable interest as a monomer for the production of polyethylene furanoate (PEF), a potential alternative for fossil-based polyethylene terephthalate (PET). This study is based on the HMF oxidizing activity shown by Mycobacterium sp. MS 16
While the so-called “end of public space” literature, focusing on encroachment of private interests and state surveillance, has contributed to critical thinking of access (or the lack thereof) to public space, and the loss of publicity of public space, the conceptual tools such literature offers to understand contestations in and over public space have remained underdeveloped or, at best, underexp
Reliable information on solar activity over the Holocene period is important to predict the Sun in the future and to understand the mechanism behind the Sun-climate linkage. Presently, there are discrepancies in the proxy data of solar activity due to reasons that are not yet understood. This leads to major uncertainties in Holocene solar reconstructions. This PhD project aims to improve the Holoc
Methane is one of the most important greenhouse gases, and the Arctic region plays an important role in its dynamics. Due to limited observations in this remote and often harsh environments, large uncertainties surround the role of the Arctic region in a warming climate. In this thesis, I examine the performance of the three low-cost solid state sensors, Figaro sensors TGS2600-B00, TGS2611-C00 an
The purpose of this article is to argue for a position holding that epigenetic responsibility primarily should be a political and not an individual responsibility. Epigenetic is a rapidly growing research field studying regulations of gene expression that do not change the DNA sequence. Knowledge about these mechanisms is still uncertain in many respects, but main presumptions are that they are tr
For many years, prostate cancer early detection was a straightforward matter of recommending biopsy to all men with an elevated prostate-specific antigen (PSA). This is perhaps best evidenced by the European Randomized Trial of Screening for Prostate Cancer, where an automatic biopsy is specified in the protocol and close to 90% of men with a PSA ≥3.0 ng/mL were biopsied [1]. Starting around 2010,
In 2020, breast cancer became the most common type of cancer worldwide. While treatment and technology have radically improved, leading to high 5-year survival, the long-term survival of breast cancer is still poor. Gene expression profiling of patients is an important source of information for outcome prediction. The Sweden Cancerome Analysis Network-Breast (SCAN-B) was initiated in 2009 and prov
Damping is present in all dynamic systems. In one way or another energy is being dissipated in the system. To capture this aspect of reality in a computational model is a difficult task. A common simplification is to assume that the damping is of a linear viscous nature. This assumption provides an equation of motion (linear dynamics) which is easy to handle mathematically. However, the simplicity of
Building on insights from ecological economics and philosophy of technology, this book offers a novel, interdisciplinary approach to understand the contradictory nature of Solar photovoltaic (PV) technology.Solar photovoltaic (PV) technology is rapidly emerging as a cost-effective option in the world economy. However, reports about miserable working conditions, environmentally deleterious mineral
When small and hollow components are being manufactured, it is not uncommon that a majority of the workpiece material is removed by machining. A demand for parts made with lead-free brass alloys can potentially increase the manufacturing cost and therefore it is necessary to investigate ways to increase the material utilization. As part of a more resource efficient production, a method for reusing
The ontogeny of the pelturine olenid trilobite Leptoplastides salteri (Callaway, 1877) from the Shineton Shales, Shropshire, England, was first described in 1925 by Frank Raw. Since that time, scanning electron microscopy and other new technologies have revealed many more details of structure, of early developmental stages in particular, than were available to Raw. Whereas protaspides are not pres
Identifying and characterizing young stars in the Solar neighbourhood is essential to find and describe planets in the early stages of their evolution. This work seeks to identify nearby young stars showing a lithium 6708 Å absorption line in the GALAH survey. A robust, data-driven approach is used to search for corresponding templates in the pool of 434 215 measured dwarf spectra in the survey. I
Our purpose with this paper was to examine the school and class situation in form nine from the pupils' own perspective, and their thoughts about ending comprehensive school. The main questions were: How do pupils in form nine describe the best vs. worst about school? How do pupils in form nine describe the relations in their class? How do pupils in form nine describe their own role/position i
This study explores Malmö's definition of social sustainability. Social sustainability still lacks a universal definition, creating a wide margin of interpretation and free space to act or not to act. The concept has grown as a topic on the political agenda and the City of Malmö has in recent years launched major projects to influence the social sustainability in a positive direction. Among ot
July-August. The Journey Summer SchoolLearn all about climate change science and start-ups over the summer! Join top-graduates on a journey across Europeand some of its best universities and businesses. Get the tools to make an impact on the global effort to find solutions to climate change and become an entrepreneur – in only three, or five weeks. You will undergo a vast development, create busin
https://www.climate-kic.lu.se/events-dates - 2026-06-29
”Det är mycket sorterande!” – Vetenskap och Hälsa Hoppa till innehåll Vetenskap och hälsa Populärvetenskapligt om medicinsk forskning i Skåne Teman Podd Tidskrift Prenumerera Om webbplatsen Kontakt Sök Sök ”Det är mycket sorterande!” 2015-03-30 ⚠️ Den här artikeln är mer än 5 år gammal. Nya forskningsrön kan ha tillkommit. Göran Karlsson är forskare på Institutionen för laboratoriemedicin vid Lund
https://www.vetenskaphalsa.se/det-ar-mycket-sorterande/ - 2026-06-29
