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Although climate is known to be one of the key factors determining animal species distributions amongst others, projections of global change impacts on their distributions often rely on bioclimatic envelope models. Vegetation structure and landscape configuration are also key determinants of distributions, but they are rarely considered in such assessments. We explore the consequences of using sim

Lotta Granbom, a mother of three from Sweden is on holiday in Thailand. It is her first trip there together with her daughter Ebba-Lotta. After some difficulty finding accommodation at the tourist resorts, they decide instead to search for Sea Nomads in the Andaman Sea. Lotta has heard of a nomadic group of people who live on the sea around Thailand, Burma, Malaysia, Singapore, Philippines and Ind

A monogenic inheritance, mainly seen as a dominant pattern, accounts for 5 - 10% of all cancer cases. The increased knowledge and identification of high-risk genes have led to a need for specialized cancer family clinic was the expression used by Eeles and Murday. The Oncogenetic Clinic at the University Hospital in Lund was started in 1993 and the authors' 10-year experience is summarized in this

It is widely accepted that the bioavaiiability, toxicity, and mobility of trace metals are highly dependent on complexation reactions with functional groups in natural organic matter (NOM). In this study, the coordination chemistry of Cd in NOM was investigated by extended X-ray absorption fine structure spectroscopy. Soil organic matter (SOM) from different types of organic soils and dissolved or

Objective: To compare the performance of the American College of Rheumatology (ACR), European League Against Rheumatism (EULAR), and simple disease activity index (SDAI) response criteria for rheumatoid arthritis at the individual level in an observational cohort. Methods: 184 outpatients were followed using a structured protocol. For each patient, the responses according to ACR 20% and 50%, EULAR

OBJECTIVES: To investigate prospectively long term patient relevant outcomes after unilateral total hip replacement (THR) for osteoarthritis (OA). To identify non-responders to this intervention and patient related predictors of unsatisfactory outcome.METHODS: A case-control study comparing health related quality of life of 219 patients (mean age 71) after THR with that of a matched reference grou

PURPOSE: To describe complications and visual outcome of photocoagulation for clinically significant macular oedema. SUBJECTS AND METHODS: Evaluation of macular oedema and complications of photocoagulation in 194 eyes, defined as subretinal fibrosis, atrophic creep of the pigment epithelium and subretinal neovascularization was based on stereo fundus photo grading. The study included 25 patients w

Sleep disordered breathing (SDB) including obstructive and central sleep apnoea/ hypopnoea as well as periodic breathing (PB) is common and is believed to increase risk for mortality in patients with congestive heart failure (CHF). Mandibular advancement device (MAD) has widely been recommended for treatment of obstructive sleep apnoea but the method has never been investigated for treatment of SD

This non-randomized prospective controlled study evaluates a daily school-based exercise intervention program of 40 min/school day for I year in a population-based cohort of 81 boys aged 7-9 years. Controls were 57 age-matched boys assigned to the general school curriculum of 60min/ week. Bone mineral content BMC; g) and areal bone mineral density (aBMD; g/cm(2)) were measured with dual X-ray abso

Objective To evaluate the outcome of screening for structural malformations in twins and the outcome of screening for twin-twin transfusion syndrome (TTTS) among monochorionic twins through a number of ultrasound scans from 12 weeks' gestation. Methods Enrolled into this prospective multicenter observational study were women with twin pregnancies diagnosed before 14 + 6 gestational weeks. The mono

To facilitate high-throughput biomarker discovery and high-density protein-chip array analyses of complex biological samples, a novel macro- and nanoporous silicon surface for protein microarrays was developed. The surface offers three-dimensional surface enlarging properties and spot confinement, enabling both high sensitivity bioassays and design of high density arrays. Reproducible manufacturin

Aims: Several studies have shown that self-rated health (SRH ) is associated with drug use. The aim of this study was to investigate the possible interaction between SRH and use of analgesics and hypnotics and its ability to predict disability pension. Methods: In 1974-78, complete birth-year cohorts of middle-aged male residents in Malmö, Sweden, were invited to a health screening, and the cohort

Background. Dosimetry of the hypothalamus-pituitary (HP) region could allow prediction of the risk of growth hormone deficiency (GHD) following cranial irradiation. Procedure. Nineteen children (15 boys) with a median age of 6.3 years (range 1.7–16.5) at the time of irradiation of a brain tumor not involving the HP axis were followed for 1.2–6.3 years (median 3.4) from radiotherapy (RT). The dose

Popular Abstract in Swedish Cytokromer bär hem som prostetisk grupp och ingår i den energi givande andningskedjan. Cytokromer namnges beroende på strukturen av den hem-molekyl som respektive cytokrom bär. Cytokrom av a-typ innehåller hemA, cytokrom av b-typ innehåller hemB osv. Cytokrom av c-typ skiljer sig från övriga cytokrom genom att ha hemgruppen kovalent bunden till proteinet. Syntes av baktCytochromes function in electron transfer reactions, e.g. in respiratory systems, and contain haem as a prosthetic group. Cytochromes of the c-type differ from other cytochromes in that haem is covalently attached, via thioether linkages, to two cysteine residues in a conserved sequence motif in the protein, Cys-Xaa-Yaa-Cys-His. The functional location of c-type cytochromes in bacteria is on the o

Neurodegenerative dementia, most frequently represented by Alzheimer's disease (AD) and dementia with Lewy bodies (DLB), is often accompanied by altered sleeping patterns and excessive daytime sleepiness. Studies showing an association between the neuropeptide orexin and AD/DLB-related processes such as amyloid-β (Aβ)1-42 plaque formation, α-synuclein accumulation, and inflammation indicate that o

Hyaluronic acid (HA) has been shown to affect angiogenesis and the function of the blood-brain barrier, and a crucial role for HA in atherosclerosis has been described. We have recently demonstrated changes in the levels of HA in cerebrospinal fluid (CSF) in patients with Alzheimer's disease (AD) with documented vascular alterations. To further investigate if the level of HA in CSF can be used as

OBJECTIVES: This study investigated the association between occupational and hobby exposure and the risk of myelodysplastic syndromes (MDS) while focusing on differential patterns of clonal chromosome aberrations and morphologic subgroups. METHODS: A case-referent study was conducted with 330 MDS patients investigated cytogenetically in 1976-1993 (cases) and matched referents. Telephone interviews