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Plasma and cerebrospinal fluid neurofilament light concentrations reflect neuronal damage in systemic lupus Erythematosus

BACKGROUND: Neuronal damage in systemic lupus erythematosus (SLE) is common, but the extent and mechanisms are unclear. Neurofilament light (NfL) concentrations rise in plasma and cerebrospinal fluid (CSF) during neuronal damage in various neurological disorders. In this cross-sectional study, plasma and CSF concentrations of NfL were explored as a marker of neuronal damage in SLE.METHODS: Seventy

Towards sustainable water use in industry: a case study of the oil refinery industry in Kazakhstan

The concept of “Sustainable water use” (SWU) aims to assure three pillars of sustainability related to the water sector: the social, environmental, and economical. Industrial development, especially in developing countries, requires an adequate response, as industrial activities are recognized as one of the major sources of water pollution, what leads to deterioration of environmental safety and w

Neoadjuvant Trastuzumab, Pertuzumab, and Docetaxel vs Trastuzumab Emtansine in Patients with ERBB2-Positive Breast Cancer : A Phase 2 Randomized Clinical Trial

Importance: Trastuzumab emtansine (T-DM1) is presently approved for treatment of advanced breast cancer and after incomplete response to neoadjuvant therapy, but the potential of T-DM1 as monotherapy is so far unknown. Objective: To assess pathologic complete response (pCR) to standard neoadjuvant therapy of combination docetaxel, trastuzumab, and pertuzumab (DTP) vs T-DM1 monotherapy in patients

Biological mechanisms of resilience to tau pathology in Alzheimer’s disease

Background: In Alzheimer’s disease (AD), the associations between tau pathology and brain atrophy and cognitive decline are well established, but imperfect. We investigate whether cerebrospinal fluid (CSF) biomarkers of biological processes (vascular, synaptic, and axonal integrity, neuroinflammation, neurotrophic factors) explain the disconnection between tau pathology and brain atrophy (brain re

Global, regional, and national burden of stroke and its risk factors, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2021

Background: Up-to-date estimates of stroke burden and attributable risks and their trends at global, regional, and national levels are essential for evidence-based health care, prevention, and resource allocation planning. We aimed to provide such estimates for the period 1990–2021. Methods: We estimated incidence, prevalence, death, and disability-adjusted life-year (DALY) counts and age-standard

Mesenchymal heterogeneity in the adult human lung

The human lung is a complex tissue consisting of a heterogeneous mix of different structures and cells, each which a specific role that together contribute to the primary function of the organ: the gas exchange. Different mesenchymal cells populate the interstitial areas around airways and blood vessels and form the connective tissue together with the extracellular matrix. Fibroblasts constitute o

Atrial Fibrillation and Clonal Hematopoiesis in TET2 and ASXL1

Importance: Clonal hematopoiesis of indeterminate potential (CHIP) may contribute to the risk of atrial fibrillation (AF) through its association with inflammation and cardiac remodeling. Objective: To determine whether CHIP was associated with AF, inflammatory and cardiac biomarkers, and cardiac structural changes. Design, Setting, and Participants: This was a population-based, prospective cohort

Normalization of puberty and adult height in girls with Turner syndrome : results of the Swedish Growth Hormone trials initiating transition into adulthood

Objective: To study the impact of GH dose and age at GH start in girls with Turner syndrome (TS), aiming for normal height and age at pubertal onset (PO) and at adult height (AH). However, age at diagnosis will limit treatment possibilities. Methods: National multicenter investigator-initiated studies (TNR 87-052-01 and TNR 88-072) in girls with TS, age 3–16 years at GH start during year 1987–1998

Abnormal cerebral hemodynamics and blood-brain barrier permeability detected with perfusion MRI in systemic lupus erythematosus patients

Objective: Dynamic susceptibility contrast (DSC) magnetic resonance imaging (MRI) has previously shown alterations in cerebral perfusion in patients with systemic lupus erythematosus (SLE). However, the results have been inconsistent, in particular regarding neuropsychiatric (NP) SLE. Thus, we investigated perfusion-based measures in different brain regions in SLE patients with and without NP invo

Disposal Behaviour and Local Support Systems

Disposal behaviour represent the last phase in the consumption cycle. From an environmental point of view it is extremely important to know the factors behind individual behaviour in waste handling. There are several aspects of interest, for example willingness of waste separation and re-use of products. The aim of this article is to analyse the importance of environmental concern, disposal behavi

Geochemical and mineralogical investigation of the Permian-Triassic boundary in the Continental Realm of the Southern Karoo Basin, South Africa

Mineralogical and geochemical studies of the non-marine Permian–Triassic (P–Tr) boundary across two stratigraphically wellconstrained sections (Commando Drift Dam and Wapadsberg, Eastern Cape Province) in the southern Karoo Basin, South Africa, have been undertaken to provide further input on the cause of this mass extinction event, and so has a sedimentological and geochemical evaluation of a thi

Predictors of long-term progression in the early manifest glaucoma trial

Purpose: To determine progression factors at the end of the Early Manifest Glaucoma Trial (EMGT) based on all EMGT patients and evaluate separately patients with higher and lower baseline intraocular pressure (IOP; median split). Design: Cohort of clinical trial participants. Participants: Patients with early open-angle glaucoma randomized to argon laser trabeculoplasty plus betaxolol (n = 129) or

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Programme code: TABIT Scope: 120 credits Cycle: Second Approved by: Programme Board BK Validity: 2018/2019 Date of approval: 21 March 2018 In addition to the syllabus, general regulations and information for the Faculty of Engineering apply to this programme. This internationally oriented master’s programme aims to pro- vide specialised theoretical knowledge in a practical technological context in

https://www.student.lth.se/fileadmin/lth/english/master/Arkiv/MBIO_Syllabus_18-19.pdf - 2026-04-20

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Programme code: TABIT Scope: 120 credits Cycle: Second Approved by: Programme Board BK Validity: 2017/2018 Date of approval: 29 March 2017 In addition to the syllabus, general regulations and information for the Faculty of Engineering apply to this programme. This internationally oriented master’s programme aims to pro- vide specialised theoretical knowledge in a practical technological context in

https://www.student.lth.se/fileadmin/lth/english/master/MBIO_Syllabus_17-18.pdf - 2026-04-20

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Programme code: TAWRE Scope: 120 credits Cycle: Second Approved by: Educational Programmes Board C Validity: 2015/2016 Date of approval: 15 April 2015 In addition to the syllabus, general regulations and information for the Faculty of Engineering apply to this programme. This internationally oriented master’s programme aims to devel- op the knowledge, skills and judgement of students in the field

https://www.student.lth.se/fileadmin/lth/english/master/MWLU_Syllabus_15-16.pdf - 2026-04-20

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Programme code: TAWRE Scope: 120 credits Cycle: Second Approved by: Educational Programmes Board C Validity: 2016/2017 Date of approval: 31 March 2016 In addition to the syllabus, general regulations and information for the Faculty of Engineering apply to this programme. This internationally oriented master’s programme aims to devel- op the knowledge, skills and judgement of students in the field

https://www.student.lth.se/fileadmin/lth/english/master/MWLU_Syllabus_16-17.pdf - 2026-04-20

Master's Programme in Fire Safety Technology

Master's Programme in Fire Safety Technology Page 1 of 5 Programme Syllabus Master's Programme in Fire Safety Technology - Programme code: TABRT - Scope: 120 credits - Cycle: Second - Approved by: Maria Wall - Validity: 2024/2025 - Date of approval: 19 February 2024 1 Aim and outcomes 1.1 Aim The Programme is an Erasmus+ Joint Programme carried out by Lund University, Ghent University, The Univers

https://www.student.lth.se/fileadmin/lth/student/Utbildningsplaner_2023_och_fram/Master_engelska/24_25/Syllabus_Master_s_Programme_in_Fire_Safety_Technology_24-25.pdf - 2026-04-20

Master's Programme in Machine Learning, Systems and Control

Master's Programme in Machine Learning, Systems and Control Page 1 of 5 Programme Syllabus Master's Programme in Machine Learning, Systems and Control - Programme code: TAMSR - Scope: 120 credits - Cycle: Second - Approved by: Programme Board F/Pi - Validity: 2024/2025 - Date of approval: 15 February 2024 1 Aim and outcomes 1.1 Aim This internationally oriented master's program aims to develop the

https://www.student.lth.se/fileadmin/lth/student/Utbildningsplaner_2023_och_fram/Master_engelska/24_25/Syllabus_Master_s_Programme_in_Machine_Learning__Systems_and_Control_24-25.pdf - 2026-04-20

Master's Programme in Fire Safety Technology syllabus

Master's Programme in Fire Safety Technology syllabus Page 1 of 5 Programme Syllabus Master's Programme in Fire Safety Technology - Programme code: TABRT - Scope: 120 credits - Cycle: Second - Approved by: Maria Wall - Validity: 2025/2026 - Date of approval: 11 February 2025 1 Aim and outcomes 1.1 Aim The Programme is an Erasmus+ Joint Programme carried out by Lund University, Ghent University, Th

https://www.student.lth.se/fileadmin/lth/student/Utbildningsplaner_2023_och_fram/Master_engelska/25_26/Syllabus_Master_s_Programme_in_Fire_Safety_Technology_25-26.pdf - 2026-04-20

Master's Programme in Machine Learning, Systems and Control

Master's Programme in Machine Learning, Systems and Control Page 1 of 5 Programme Syllabus Master's Programme in Machine Learning, Systems and Control - Programme code: TAMSR - Scope: 120 credits - Cycle: Second - Approved by: Programme Board F/Pi - Validity: 2025/2026 - Date of approval: 13 February 2025 1 Aim and outcomes 1.1 Aim This internationally oriented master's program aims to develop the

https://www.student.lth.se/fileadmin/lth/student/Utbildningsplaner_2023_och_fram/Master_engelska/25_26/Syllabus_Master_s_Programme_in_Machine_Learning__Systems_and_Control_25-26.pdf - 2026-04-20