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Activated porcine embryonic brain endothelial cells induce a proliferative human T-lymphocyte response

Transplantation of allogeneic embryonic neural tissue is a potential treatment for patients with Parkinson's and Huntington's diseases. The supply of human donor tissue is limited, and alternatives such as the use of animal (e.g., porcine) donor tissue are currently being evaluated. Before porcine grafts can be used clinically, strategies to prevent neural xenograft rejection must be developed. Kn

Antileukoproteinase - Modulation of neutrophil function and therapeutic effects on anti-type II collagen antibody-induced arthritis

Objective. Antileukoproteinase (ALP) is a physiologic inhibitor of granulocytic serine proteases. The present study was undertaken to investigate its therapeutic benefit in an antibody-transfer model of erosive polyarthritis and to elucidate its potential to interfere with immune complex-dependent inflammatory pathways. Methods. Arthritis development was induced in male (BALB/c x B10.Q)F-1 mice by

Immune responses following meningococcal serogroups A, C, Y and W polysaccharide vaccination in C2-deficient persons: Evidence for increased levels of serum bactericidal antibodies.

Complement C2 deficiency (C2D) is associated with immunological diseases and increased susceptibility to invasive infections caused by encapsulated bacteria such as Neisseria menigitidis. In this study we evaluate the immunogenicity of vaccination against N. menigitidis in C2D. C2D patients (n=22) and controls (n=52) were given a tetravalent meningococcal polysaccharide vaccine. Serum bactericidal

γ-globulins prepared from sera of multiparous women bind anti-HLA antibodies and inhibit an established in vivo human alloimmune response

It has previously been shown that sera from multiparous women have increased levels of anti-idiotypic antibodies specific for anti-HLA molecules. γ-Globulins prepared from these sera may be superior to commercial preparations of intravenous γ-globulin (IVIg) for inhibiting HLA alloimmunization. To test this, F(ab′)2 fragments prepared from either commercial IVIg or from the sera of men or multipar

TFPI-2 protects against gram-negative bacterial infection

Tissue factor pathway inhibitor-2 (TFPI-2) has previously been characterized as an endogenous anticoagulant. TFPI-2 is expressed in the vast majority of cells, mainly secreted into the extracellular matrix. Recently we reported that EDC34, a C-terminal peptide derived from TFPI-2, exerts a broad antimicrobial activity. In the present study, we describe a previously unknown antimicrobial mode of ac

Plasmodium falciparum transmission based on merozoite surface protein 1 (msp1) and 2 (msp2) gene diversity and antibody responses in Ibadan, Nigeria

Background: Nigeria is a major contributor to the global malaria burden. The genetic diversity of malaria parasite populations as well as antibody responses of individuals in affected areas against antigens of the parasite can reveal the transmission intensity, a key information required to control the disease. This work was carried out to determine the allelic frequency of highly polymorphic Plas

C-terminal TFPI-1-derived peptides: their evolutionary host defense functions

Antimicrobial peptides (AMPs) are evolutionarily ancient molecules. They are essential innate immune response molecules that protect organisms from invading pathogens. Tissue factor pathway inhibitors (TFPI-1 and TFPI-2) C-terminal derived peptides exert host defense mechanisms against microbes. Studies showed that in human plasma, C-terminal TFPI-1 and -2 derived peptides mediate bacterial killin

Novel peptide ligand with high binding capacity for antibody purification

Small synthetic ligands for protein purification have become increasingly interesting with the growing need for cheap chromatographic materials for protein purification and especially for the purification of monoclonal antibodies (mAbs). Today, Protein A-based chromatographic resins are the most commonly used capture step in mAb down stream processing; however, the use of Protein A chromatography

Kp SMMX36 eng HT24 rev 240216

Syllabus SMMX36 Transport Systems Management This is a translation of the syllabus which was established in Swedish. Faculty of Social Sciences SMMX36, Transport Systems Management, 7.5 credits Ledning av transportsystem, 7,5 högskolepoäng Second Cycle / Avancerad nivå Details of approval The syllabus was approved by the board of the Department of Service Management and Service Studies on 2021-02-

https://www.ses.lu.se/en/sites/ses.lu.se.en/files/2024-02/Kp_SMMX36_eng_HT24_rev_240216.pdf - 2026-05-07

European-Code-of-Conduct-Revised-Edition-2023

1 The European Code of Conduct for Research Integrity REVISED EDITION 2023 Published in Berlin by ALLEA | All European Academies June 2023 Citation For citation purposes, please use the following: ALLEA (2023) The European Code of Conduct for Research Integrity – Revised Edition 2023. Berlin. DOI 10.26356/ECOC ISBN 978-3-9823562-3-5 Licence This work is licensed under the terms of the Creative Com

https://www.more-lab.lu.se/sites/more-lab.lu.se/files/2024-01/European-Code-of-Conduct-Revised-Edition-2023.pdf - 2026-05-07

Work environment & health at the Department of Informatics

FOR EMPLOYEES AT THE DEPARTMENT OF INFORMATICS At the Department of Informatics it is important that we create and maintain a good and safe work environment free from discrimination. The Department works systematically, continuously and preventively with work environment in accordance with the University’s routines and guidelines of SAM (systematiskt arbetsmiljöarbete). The work is monitored annua

https://www.lusem.lu.se/internal/department-staff-pages/department-informatics/work-environment-health-department-informatics - 2026-05-05

Övervakning av fåglarnas populationsutveckling. Årsrapport för 2020.

I denna rapport redovisas populationstrender för 228 svenska fågelarter för olika långa tidsperioder. Vi visar också korttidstrender för 12 arter av större däggdjur. Fåglarna har räknats höst, vinter, vår och sommar enligt strikt standardiserade metoder. Sommar- respektive vinterpunktrutter har räknats sedan 1975, i huvudsak i södra Sverige. Standardrutterna räknas också på sommaren (sedan1996) meWe present the results of the Swedish Bird Survey, run by the Department of Biology, Lund University, as a part of the National Monitoring Programme of the Swedish Environmental Protection Agency. The results for 2020 include data from: 564 winter point counts in 2019/2020 (45th winter), of which 274 were carried out during the Christmas/New Year count, 210 summer point count routes (46th year) an

Control of an Oscillatory System

Systems with structural resonances are difficult to control if fast responses are required. Rapid changes in the control signal may excite the resonant modes. In digital control with zero-order-hold sampling there will be very rapid changes in the control signal. A way to deal with the problem is to use predictive first-order-hold sampling instead. The control signal is then linear between the sam