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BACKGROUND: Fibroblast growth factor 23 (FGF23), a bone-derived hormone that regulates phosphorus and vitamin D metabolism, contributes to the pathogenesis of mineral and bone disorders in CKD and is an emerging cardiovascular risk factor. Central elements of FGF23 regulation remain incompletely understood; genetic variation may help explain interindividual differences.METHODS: We performed a meta
Current electrode technologies are too rigid for safe and effective delivery of electrotherapy in the brain, and patients with glioblastoma continue to face a devastating prognosis, with median survival stalled at 15 months despite intensive treatment with surgery, radiation, and chemotherapy. But these conventional approaches potentially compromise immune function, underscoring the urgent need fo
Obesity may exacerbate colorectal cancer (CRC) prognosis, yet previous studies have shown inconsistent findings due to methodological limitations. In this nationwide cohort study, we investigated the association between body mass index (BMI) on CRC recurrence and mortality, while examining the influence of demographic, clinical, and socioeconomic characteristics. From the Danish Colorectal Cancer
Research on air travellers’ willingness to pay (WTP) for climate change mitigation has focussed on voluntary emissions offsetting so far. This approach overlooks policy relevant knowledge as it does not consider that people may value public goods higher if they are certain that others also contribute. To account for potential differences, this study investigates Swedish adults’ WTP for a mandatory
This Mutual Learning Exercise (MLE) on Innovation-related Procurement was conducted under the Horizon 2020 Policy Support Facility run by the European Commission’s Directorate-General for Research and Innovation. The 15 countries that participated were: Austria, Belgium - Brussels Region, Estonia, France, Germany, Greece, Latvia, Lithuania, Netherlands, Norway, Portugal, Slovenia, Spain, Sweden an
BackgroundDementia is a syndrome, with a wide range of symptoms. It is important to have a timely diagnosis during the disease course to reduce the risk of medication errors, enable future care planning for the patient and their relatives thereby optimizing quality of life (QoL). For this reason, it is important to avoid a diagnosis of dementia not otherwise specified (DNOS) and instead obtain a d
Background: Hereditary ataxia is a group of rare disorders. Healthcareproviders and public authorities may have limited knowledge about thisdiagnosis. We asked the patients if they feel well-informed about thediagnosis and whom they usually turn to for support.Methods: Adult patients with a diagnosis of progressive cerebellar ataxiawere identified in the diagnosis register of Scania region or were
Background: Process evaluations are an important component in the interpretation and understanding of outcomes in trials. The Online Remote Behavioural Intervention for Tics (ORBIT) study is a randomized controlled trial evaluating the effectiveness of an Internet-delivered behavioural intervention (called BIP TIC) compared to an Internet-delivered education programme aimed at children and young p
This qualitative theological study seeks to shed light on pentecostal theology and spirituality through an investigation of worship as it is practiced in two urban pentecostal-charismatic churches in Nairobi, Kenya. The empirical data serve as a springboard for theological construction and interpretation from a pentecostal perspective. In contemporary charismatic liturgy, the first section of the
För mindre och nystartade aktiebolag kan finansiering vara ett gissel, särskilt om den verksamhet som bedrivs i bolaget är kostsam eller förenad med hög finansiell risk för potentiella finansiärer. Sådan är situationen ofta i det som i folkmun kallas ”startups”, då bolagen frekvent bygger på enbart en idé eller en outvecklad produkt, och därmed utgör mycket osäkra investeringar för poten- tiella fFunding for a small or newly established limited company can be difficult, especially if the operating objective in the company is associated with high costs and high financial risks for potential financiers. This is often the case for so called “start-ups”, as these types of companies are frequently based on an idea or an undeveloped product. Investing in a start-up is very risky for pot- ential
Understanding material behaviour has in the past enabled human development and will continue to characterize the various stages of our future development. The use of neutrons will greatly affect several research areas, such as sustainable energy production and cancer research, due to their interaction with nuclei. Neutrons will thus interact differently depending on the specific isotope, reveal in
Populärvetenskaplig sammanfattning av examensarbetet Utveckling av karaktäriserings-metoder för lignocellulosarika biogassubstrat. Smältande isar, extrema naturkatastrofer och rekordhöga temperaturer; det rapporteras daglig-en om nya händelser som påstås ha orsakats av den globala uppvärmningen. De flesta svenskar är numer familjära med uttrycket och miljömedvetenhet är något som blir mer och mer As the need of environmentally friendly alternatives to fossil fuels is growing bigger, so is the need for knowledge and research around possible new raw materials that could serve that pur-pose. One discussed product is biogas. Since biogas can be produced from not only food waste and wastewater residue, but from any substrate that contains fats, proteins and/or car-bohydrates, with the help of d
Småskalig plattform för upprening av monoklonala antikroppar Utvecklingen av en uppreningsplatform för antikroppar visar en 30% ökning i produk-tivitet med hjälp av parallella flödesbanor. Det är nu också möjligt att upprena ännu fler prov per körning än tidigare. Utvecklingen av nya antikroppar blir allt mer viktigare i dagens samhälle för att kunna förbättra vår analytiska och diagnostiska föThe aim of this project is to transfer and implement a monoclonal antibody purification process that is traditionally done on an ÄKTAxpress to another machine called the ÄKTA pure. This is due to the fact that the ÄKTAxpress is being discontinued by the manufacturer and a replace-ment machine is needed for the time being. The project will include developing some new meth-ods that might also highli
Popular science summary: Huntington’s disease (HD) is a rare disease but more commonly found in ethnic populations belonging to Europe and North America than in those of Asian or African ancestry. This disease causes loss of neurons in different areas of the brain, that gives rise to different behavioural changes and psychological disturbances including involuntary movements and depression. The
Today most companies have online sales channels. Most commonly have companies started offline and then later expanded online while others have started their business online through, for example, web shops. Even though we today are living in a high technology society, the existence of an offline sales channel is still needed. But what is the exact definition of a sales channel really? In today’s
Populärvetenskaplig sammanfattning: Småvatten är en svacka eller hålighet som är vattenfylld året om. Dessa småvatten fyller många viktiga funktioner i naturen. De fungerar som utjämnare av flödesvariationer, uppehållsplats och födoplats för många djur och växter och som rena estetiska inslag i naturen, och inte minst som reningsplatser för oönskade näringsämnen så som kväve. Dessa småvatten har iWetlands play an important role in the ecosystem. They reduce the impact of flow flux in the drainage area, acts as upholder of biodiversity, as an esthetic and recreational component in the landscape and they have the ability to reduce nutrients such as nitrogen, and help preventing eutrophication in costal areas. The number of wetlands in Scania have, due to the intensified agriculture been redu
Objectives:To determine the cumulative live birth rate (CLBR) under three consecutive in vitro fertilisation (IVF) treatments in women with endometriosis and/or adenomyosis.Methods:A prospective cohort study of 1035 women aged 25–≤39 years undergoing up to three consecutive IVF treatments between January 2019 and April 2024. All women underwent an advanced transvaginal ultrasound examination prior
The international humanitarian system has, since the 19th century, been activated during large-scale disasters when the capacities of the affected countries are overwhelmed. It comprises international humanitarian organizations (IHOs) and is funded by a variety of donors. Recently, this system has faced increasing criticism, mainly because of its failure to empower and include local and national a
Titel: Validering av en handledsburen aktivitetsmätare och en självskattningskala för beräkning av VO2max. Bakgrund: Fysisk aktivitet och god aerob kapacitet är kopplat till god hälsa och lägre risk för livsstilsrelaterade sjukdomar. I dagsläget anses maximalt arbetsprov med ergospirometri och gasanalys för bestämning av VO2max (VO2max-test) vara det mest exakta sättet att mäta aerob kapacitet. Su
