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Carbonic anhydrase (CA) is a thoroughly studied enzyme. Its primary role is the rapid interconversion of carbon dioxide and bicarbonate in the cells, where carbon dioxide is produced, and in the lungs, where it is released from the blood. At the same time, it regulates pH homeostasis. The inhibitory function of sulfonamides on CA was discovered some 80 years ago. There are numerous physiological-t
BACKGROUND: Itch is a common symptom in the general population. Affected individuals often do not seek medical consultation and rely on Internet searches to obtain information regarding their itch.OBJECTIVES: The aim of this study was to attain insights into common concerns of the general population regarding itch can by analysing itch-related Internet search behaviour.METHODS: Google AdWords Keyw
The purpose of this thesis is to further investigate the state of matter known as Quark-Gluon Plasma (QGP) that is produced in heavy ion collisions. This is done by analyzing jets and jet quenching in Pb-Pb collisions at $\sqrt[]{s_\textrm{NN}}$ = 2.76 TeV from ALICE. The events are discriminated by setting a 8 GeV/$c$ $p_\textrm{T}$ threshold on the trigger particle. This ensures that there is ha
The Standard Model does not predict the quantization of electric charge, and thus does not explicitly demand the electric neutrality of the neutron. This charge has previously been measured to an upper limit of ∼ 1 × 10^−21 elementary charges in a 1988 joint experiment between the University of Bayreuth and Institut Laue-Langevin [1]. A new experiment proposed for the HIBEAM beamline at the ESS is
The infrastructure for the third generation of mobile telephony, UMTS, is under construction in Sweden. Within three years four operators were to build competing systems to cover 99,98 % of the population. The case of the 3G infrastructure illustrates how the sustainability issues are handled in planning and environmental management, with conflicting goals between institutional levels and compet
Personal på sjukhusavdelningar upplever ett antal problem kopplade till administrativa uppgifter. Bland dessa problem ingår att behöva dokumentera samma information i flera system, samt svårigheter vid överlämningar mellan skift. Den nuvarande produkten Pulstavlan, utvecklad av Stretch Care AB, har som mål att lösa dessa problem. Pulstavlan är dock stationär och möjliggör därför inte för vårdpersoStaff in hospital wards experience a number of issues related to administrative tasks. These problems include needing to document the same information in multiple systems, and difficulties in shift handovers between staff members. The existing product Pulstavlan, developed by Stretch Care AB, aims to solve these issues. However, as the product is stationary, it does not enable staff to bring the i
Background: The causes of obsessive-compulsive disorder (OCD) remain unknown. Gene-searching efforts are well underway, but the identification of environmental risk factors is at least as important and should be a priority because some of them may be amenable to prevention or early intervention strategies. Genetically informative studies, particularly those employing the discordant monozygotic (MZ
The global pandemic has initially negatively influenced the financial markets all over the world. As a consequence, the volatility in the stock markets increased and investors have experienced great monetary losses. In addition, the volatility spillover has increased between different markets and assets, which additionally amplifies the negative influence by the pandemic. This motivates the search
