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When natural areas are converted for human use, resulting changes in the landscape often lead to habitat loss and fragmentation, which can disrupt key ecological interactions such as pollination by animals. In this study, we investigated the independent effects of habitat loss and fragmentation on the structure and composition of plant-vertebrate pollinator interaction networks, focusing on intera
Background Childhood vaccination rates fluctuate over time and do not always meet the levels recommended by the WHO. Objective This study aims to provide an overview of measures countries have introduced to increase vaccination rates. Methods We developed a structured data collection template that was completed by country experts from Europe, Israel, the USA, and Canada. Experts were identified us
Anthropogenic noise and artificial light at night (ALAN) are expanding globally, acting as pervasive sensory pollutants that can disrupt wildlife behaviour and reproduction. While most research has focused on diurnal species, the effects of these pollutants on the ecological response of nocturnal predators remain poorly understood. Using data from nine European countries, we investigated the effec
The aim of this study was to perform histopathological reassessment of primary resections of locally advanced colon cancer (CC) within a randomized controlled trial, with specific focus on surgical margins and synchronous locoregional peritoneal metastases (SL-PM), and to provide learning points for both surgeons and pathologists. All histopathological slides of patients with c/pT4N0-2M0 or perfor
Anthropomorphic activities have a large impact on ecosystems in many ways, one of which is how animals behave. Non-motorised nature recreation is a popular human activity of which the impacts on nature are largely unknown. These activities, which include hiking, biking, pet walking and horseback riding, tend to increase during the commencement of the breeding activity for most passerine forest bir
Protein–protein interactions are fundamental to biological functions as well as the design of new functional food products and biomedicines. However, they can be challenging to computationally quantify due to strong forces and sensitivity to pronounced solution conditions. This thesis combines computational methods with Monte Carlo simulations to investigate strong protein interactions in diverse
Rochechouart, south-west France, is a complex impact structure. Here, we present the first report of shock barometry of quartz from what are likely parautochthonous basement units at depth, based on samples from the 2017 C.I.R.I.R drilling campaign. The crystallographic orientations of 725 sets of PDFs in 512 quartz grains in samples from four drill cores were measured. We find basal PDFs (Brazil
Objective: Assessing psychological pain is crucial for evaluating suicide risk. This study examined differences in psychological pain between patients with suicide attempts, those with suicidal ideation, clinical, and non-clinical controls using a newly translated German version of the Mee-Bunney Psychological Pain Assessment Scale (MBPPAS). Method: A cross-sectional study was conducted with two i
Passive seismic data were acquired together with active seismic data along a 2.8 km long profile in the Sudret area of Gotland, Sweden, as part of a feasibility study for storage of CO2 below the Baltic Sea. Seismic interferometry using cross-correlation and cross-coherence was employed on the passive seismic data. Cross-correlation was used to retrieve virtual shot gathers containing mainly surfa
Telomerase reverse transcriptase (TERT) activity is up-regulated in several types of tumors including glioblastoma (GBM). In the present study, 128 primary glioblastoma patients were examined for single nucleotide polymorphisms of TERT in blood and in 92 cases for TERT promoter mutations in tumors. TERT promoter mutations were observed in 86% of the tumors and of these, C228T (-124 bp upstream sta
New alternatives for treatment of overactive bladder (OAB) syndrome are continuously being explored. Despite ongoing nonclinical and clinical research, few new principles have evolved. We can expect future new additions to existing drug classes and different combinations of existing options. New antimuscarinics are in development, but we do not know if they offer any advantages to currently availa
The study investigates how the Best Interests of the Child principle in the UN Children's Rights Convention (Article 3) has been adapted in custody disputes in Egypt, Sweden, and Uzbekistan. Although the Convention on the Rights of the Child offers a common normative benchmark, divergent legal cultures shape its domestic meaning: Egypt is governed by religious and state legal norms intersecting wi
The PRIMARY score was implemented in Prostate Cancer Molecular Imaging Standardized Evaluation (PROMISE) version 2 to improve accuracy for the diagnosis of clinically significant prostate cancer using prostate-specific membrane antigen (PSMA) positron emission tomography (PET). We reviewed overall survival (OS) for patients who underwent PSMA PET for initial staging to evaluate the prognostic valu
Segmentation of grey matter in magnetic resonance images of the spinal cord is an important step in assessing disease state in neurological disorders such as multiple sclerosis. However, manual delineation of spinal cord tissue is time-consuming and susceptible to variability introduced by the rater. We present a novel segmentation method for spinal cord tissue that uses fully convolutional encode
AbstractDead standing trees (DSTs) generally decompose slower than wood in contact with the forest floor. In many regions, DSTs are being created at an increasing rate due to accelerating tree mortality caused by climate change. Therefore, factors determining DST fall are crucial for predicting dead wood turnover time but remain poorly constrained. Here, we conduct a re-analysis of published DST f
Gambling disorder is a major public health issue in many countries. It has been defined as a persistent, recurrent pattern of gambling and is associated with substantial distress or impairment, lower quality of life, and living with a plurality of psychiatric problems. Many people suffering from gambling disorder seek help in ways other than formal treatment seeking, including self-management stra
The Arctic temperature changes are closely linked to midlatitude weather variability and extreme events, which has attracted much attention in recent decades. Syntheses of proxy data from poleward of 60g gN indicate that there was asymmetric cooling of-1.54 and-0.61gg C for the Atlantic Arctic and the Pacific Arctic during the Holocene, respectively. We also present a similar consistent cooling pa
Patients admitted to intensive care after cardiac arrest are at risk of circulatory shock and early mortality due to cardiovascular failure. The aim of this study was to evaluate the ability of the veno-arterial pCO2 difference (∆pCO2; central venous CO2 – arterial CO2) and lactate to predict early mortality in postcardiac arrest patients. This was a pre-planned prospective observational sub-study
