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Glucose-evoked insulin secretion exhibits two phases: The first phase represents exocytosis of insulin granules situated at the plasma membrane, whereas the second phase reflects insulin release from granules continuously recruited to the plasma membrane. This thesis investigates different aspects of phasic insulin secretion, with the specific aims to elucidate the possible contribution of insulin

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The Proton Exchange Membrane (PEM) fuel cell has been investigated for a long time, and is regarded as a new energy source for various applications, such as portable, stationary and automotive ones. However, due to the shortage of the infrastructure in the society, the high cost, the difficulty of the water/thermal management, etc., practical systems have not reached the general public, yet. Of t

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Popular Abstract in Swedish Många fåglar flyttar regelbundet långa sträckor mellan sina häckningsplatser och vinterkvarter. På rastningsplatser längs flyttningsvägen stannar fåglarna upp och äter, för att lagra upp de energi-lager de behöver som bränsle när de flyger. Vissa flyttfåglar lägger på sig så mycket bränsle (energi), mestadels som fett, att de dubblar sin kroppsvikt. Det lagrade bränslet

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Construction in rock is associated with risks because knowledge of the geology and ground conditions is limited. Unforeseen rock conditions involve a large risk to the project and can in the end entail delays and extra costs. To minimize the risks, an optimized pre-investigation program has to be conducted where essential information is gathered in order to make the best decisions throughout the c

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Load problems in electricity markets occur both on the supply and demand side and can have technical, economic and even political causes. Commonly, such problems have been solved by expanding production and/or distribution capacity, importing electricity or by load management. Load management is a techno-economic measure for harmonizing the relations between supply and demand sides, optimizing pow

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In order to better assess the role of agriculture within the global climate-vegetation system, we present a model of the managed planetary land surface, Lund-Potsdam-Jena managed Land (LPJmL), which simulates biophysical and biogeochemical processes as well as productivity and yield of the most important crops worldwide, using a concept of crop functional types (CFTs). Based on the LPJ-Dynamic Glo

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In the course of 2000s, the region of Campania in southern Italy and its capital city Naples became global icons of waste mismanagement after the images of piles of rubbish occluding their urban areas hit the headlines. Conventional explanations, in Italy and elsewhere, pointed to administrative failure, cultural backwardness and mafia infiltration as the main causes of waste mishandling. In the s

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Recent investigations of the DNA interactions with cationic surfactants and catanionic Mixtures are reviewed. Several techniques have been used such as fluorescence microscopy, dynamic light scattering, electron microscopy, and Monte Carlo simulations. The conformational behaviour of large DNA molecules in the presence of cationic surfactant was followed by fluorescence microscopy and also by dyna

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Popular Abstract in Swedish Winnicott definierade och införde begreppen övergångsobjekt (ÖO) och övergångsfenomen (ÖF) vid ett möte i brittiska psykoanalytiska föreningen i maj 1951. Detta kopplades till ett tänkande, som gällde utvecklingen av barnets relaterande från en från början alltigenom subjektiv upplevelsevärld till en värld med ”verkliga” relationer - och talade om ”the intermediate areaThe central issue of the dissertation is the place and meaning of the concepts transitional object (TO) and transitional phenomenon (TP) as defined by Winnicott, in a normal psychological context. A group of children were followed from age 8 months to 6 years. A prevalence study was carried out by interviewing parents in connection with the child's (n=147) routine check-ups at the Child Health Cen

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Several beneficial effects have been connected with dietary fibre. Insoluble fibre has a good faecal bulking capacity, whereas soluble and viscous dietary fibre has been shown to have beneficial effects on carbohydrate and lipid metabolism. Fruit and vegetables provide about one third of the dietary fibre intake in Northern Europe and more than half in Mediterranean countries. These food items are

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Popular Abstract in English Lions (Panthera leo) have become known to be synonymous with wild Africa since its extinction from most parts of its former range (Europe, Asia and Southern America). Few people realize that anthropogenic activities have caused habitat loss, fragmentation and reduction in size to the lions, forcing them to the brink of extinction. Whenever out in nature, most tourists tHigh growth rate in human populations, agricultural developments and industrialization have impinged negatively on the natural habitats of most large carnivores, causing fragmentation, isolation and consequently reduction in population size. Lions (Panthera leo) that once roamed most parts of Southern Europe, Asia, the Middle East, North America, northern part of South America and most parts of Af

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Popular Abstract in Swedish Hjärt-kärlsjukdom är en av västvärldens stora folksjukdomar. I Sverige drabbas årligen cirka 10 000 personer av plötsligt hjärtstopp. Den vanligaste orsaken är att en akut hjärtinfarkt orsakar ett ”elektriskt kaos” i hjärtat. Vid ett hjärtstopp upphör blodförsörjningen till hjärnan, vilket leder till medvetslöshet inom några sekunder och inom några få minuter börjar hjäThis thesis focuses on the prognostic value of electroencephalography(EEG) in comatose patients resuscitated after cardiac arrest (CA), using both simplified continuous EEG monitoring (cEEG) and routine EEG. Background: Comatose survivors are admitted to an intensive care unit (ICU) to support vital functions. Postresuscitation care includes target temperature management (TTM) for 24 hours. The d

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This thesis focuses on cognitive impairment in Out-of-Hospital Cardiac Arrest (OHCA) survivors with the main aim to evaluate possible effects by targeted temperature management. Secondary aims are to describe the prevalence of cognitive impairment in a large group of OHCA-survivors, the related symptoms of psychological distress and the actual effect of cognitive impairment for the patient’s abili

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This thesis deals with the international rules regarding passenger liability on an international aircraft. The focus will be the carrier's liability toward passengers on an aircraft. The purpose is to give an account of the common international rules and to clarify the problems with interpretation of the passenger liability article. I will focus on the Montreal Convention of 1999, which is the

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Purpose: The purpose of this study is to explore how brand managers align their brand identity within online brand communities where the communication is shared in order to create a reinforcing point of contact instead of a source of mixed messages. Problem: With the increasing usage of the internet, brand managers are today forced and challenged to align and re-enforce a brand’s identity online w

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Läckage och spill från cisterner utgör de vanligaste orsakerna till förorening av grundvatten med petroleumprodukter. Bensin och dieselföroreningar sprids inte enbart längs grundvattenytan utan lösta beståndsdelar kan transporteras med grundvattnet relativt långa sträckor. Flyktiga kolväten förflyttar sig i den vattenmättade zonen beroende på föroreningens utbredning och fördelning. Flera tusen aSpills and leaks from storage tanks constitute the most common groundwater contamination source with petroleum products. Gasoline and diesel pools do not spread extensively along the water table, but dissolved constituents are transported in groundwater on relatively larger distances. Volatile hydrocarbons migrate in the vadose zone dependently on distribution and extent of the dissolved and pure

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Detta arbete har som syfte att besvara två frågeställningar - hur ser lagstiftningen ut för miljökonsekvensbeskrivningar för planer och program i Sverige, och vilka krav kan ställas utifrån denna, samt hur dessa krav har uppfattats i genomförda miljökonsekvensbeskrivningar för planer och program? Detta görs genom en genomgång av lagtext, förarbeten, praxis och litteratur på området, en granskning This work aims to answer two questions - how does the legislation for environmental impact assessments for plans and programs in Sweden look like, and what demands can be made from this, and how are these requirements perceived in conducted environmental impact assessments for plans and programs? This is done through a review of the statutory text, legislative history, case law and literature, an

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Popular Abstract in Swedish Förekomsten av hudcancer ökar i ljushyade befolkningsgrupper och hudcancer tillhör de cancergrupper som ökar mest i Sverige. De tre vanligaste formerna av hudcancer är basalcellscancer, skivepitelcancer och malignt melanom. Under 2013 utgjorde skivepitelcancer och malignt melanom ca 16 % av alla cancerfall som rapporterades in till Svenska Cancerregistret; över 6 000 faSkin cancer incidence is increasing in fair-skinned populations. The three most common skin cancers are basal cell carcinoma (BCC), squamous cell carcinoma (SCC) and malignant melanoma (MM). A correct diagnosis is crucial for an efficient and tailored treatment for the skin cancer patient. The purpose of this thesis was to evaluate different aspects of the preoperative diagnosis of skin cancer. Th

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Critics maintain that there are a number of troublesome issues resulting from the construction sector’s way of operating and that these remain, despite widespread criticism and measures designed to change all of this. The construction sector’s and the critics’ manner of describing these problems fails to a large extent to take into consideration the way people function in connection with practical